HitPredict

Interactor 1: STK25 (O00506)
Serine/threonine-protein kinase 25 (EC 2.7.11.1) (Ste20-like kinase) (Sterile 20/oxidant stress-response kinase 1) (SOK-1) (Ste20/oxidant stress response kinase 1)
Gene: STK25

Interactor 2: SIKE1 (Q9BRV8)
Suppressor of IKBKE 1 (Suppressor of IKK-epsilon)
Gene: SIKE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	18782753, 32707033, 23455922
Identification Methods	affinity chromatography technology, pull down, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 426 Hs			1 207
+	Hs
		1310721 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00
+	Hs
		72975 B4DR80_HUMAN (10-416): 2.38e-139: 406: 68.46		SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00
+	Hs
		1310712 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00
+	Hs
		131613 STK25_HUMAN (1-426): 4.51e-156: 449: 100.00		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Hs
		1346716 STK24_HUMAN (8-424): 7.71e-143: 416: 71.12		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Hs
		72977 B4DR80_HUMAN (10-416): 2.38e-139: 406: 68.46		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Hs
		1346705 STK26_HUMAN (15-420): 4.41e-138: 403: 67.32		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Hs
		1240585 Q8NBY1_HUMAN (15-420): 1.31e-131: 386: 64.29		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Dm
		1249843 HIPPO_DROME (3-385): 3.61e-120: 366: 39.79		FGOP2_DROME (4-189): 6.51e-55: 178: 30.00
+	Hs
		1027445 STK3_HUMAN (2-295): 3.42e-128: 380: 51.01		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Hs
		1023126 STK4_HUMAN (3-284): 1.11e-127: 379: 52.80		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50
+	Hs
		1310716 TNIK_HUMAN (15-293): 6.7e-72: 247: 45.97		SIKE1_HUMAN (1-207): 1.94e-70: 215: 100.00
+	Hs
		1346707 TNIK_HUMAN (15-293): 6.7e-72: 247: 45.97		FGOP2_HUMAN (1-203): 1.23e-47: 158: 43.50