Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
SMUF2
E3 ubiquitin-protein ligase SMURF2 |
17 |
18 |
Small-scale |
0.986 | High |
|
|
UB2D3
Ubiquitin-conjugating enzyme E2 D3 |
12 |
20 |
Small-scale |
0.978 | High |
|
|
UB2L3
Ubiquitin-conjugating enzyme E2 L3 |
11 |
20 |
Small-scale |
0.978 | High |
|
|
UBC
Polyubiquitin-C [Cleaved into: Ubiquitin] |
8 |
20 |
Small-scale |
0.963 | High |
|
|
SMUF1
E3 ubiquitin-protein ligase SMURF1 |
6 |
19 |
Small-scale |
0.943 | High |
|
|
UB2D1
Ubiquitin-conjugating enzyme E2 D1 |
4 |
20 |
Small-scale |
0.914 | High |
|
|
NEDD4
E3 ubiquitin-protein ligase NEDD4 |
4 |
17 |
Small-scale |
0.899 | High |
|
|
UB2D2
Ubiquitin-conjugating enzyme E2 D2 |
2 |
20 |
Small-scale |
0.778 | High |
|
|
SMAD7
Mothers against decapentaplegic homolog 7 |
19 |
20 |
Small-scale |
0.766 | High |
|
|
SMAD2
Mothers against decapentaplegic homolog 2 |
14 |
20 |
Small-scale |
0.762 | High |
|
|
SMAD3
Mothers against decapentaplegic homolog 3 |
13 |
20 |
Small-scale |
0.761 | High |
|
|
SMAD1
Mothers against decapentaplegic homolog 1 |
11 |
20 |
Small-scale |
0.759 | High |
|
|
TGFR1
TGF-beta receptor type-1 |
8 |
19 |
Small-scale |
0.741 | High |
|
|
RNF11
RING finger protein 11 |
6 |
15 |
Small-scale |
0.740 | High |
|
|
NEDD8
Ubiquitin-like protein NEDD8 |
1 |
19 |
Small-scale |
0.724 | High |
|
|
SMAD5
Mothers against decapentaplegic homolog 5 |
5 |
20 |
Small-scale |
0.719 | High |
|
|
UBB
Polyubiquitin-B [Cleaved into: Ubiquitin] |
2 |
20 |
Small-scale |
0.712 | High |
|
|
TRAF4
TNF receptor-associated factor 4 |
4 |
15 |
Small-scale |
0.707 | High |
|
|
RHOA
Transforming protein RhoA |
4 |
20 |
Small-scale |
0.686 | High |
|
|
EGFR
Epidermal growth factor receptor |
3 |
20 |
Small-scale |
0.678 | High |
|
|
RHG05
Rho GTPase-activating protein 5 |
3 |
7 |
High-throughput |
0.674 | High |
|
|
LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4 |
3 |
12 |
High-throughput |
0.667 | High |
|
|
SMAD6
Mothers against decapentaplegic homolog 6 |
3 |
20 |
Small-scale |
0.650 | High |
|
|
KLF5
Krueppel-like factor 5 |
2 |
10 |
Small-scale |
0.643 | High |
|
|
TGFR2
TGF-beta receptor type-2 |
3 |
19 |
Small-scale |
0.640 | High |
|
|
SMAD4
Mothers against decapentaplegic homolog 4 |
3 |
20 |
Small-scale |
0.640 | High |
|
|
PARP1
Poly [ADP-ribose] polymerase 1 |
2 |
7 |
Small-scale |
0.634 | High |
|
|
CUED1
CUE domain-containing protein 1 |
4 |
8 |
Small-scale |
0.630 | High |
|
|
TYY1
Transcriptional repressor protein YY1 |
2 |
4 |
Small-scale |
0.624 | High |
|
|
ID1
DNA-binding protein inhibitor ID-1 |
2 |
3 |
Small-scale |
0.624 | High |
|
|
BRE1A
E3 ubiquitin-protein ligase BRE1A |
2 |
4 |
Small-scale |
0.624 | High |
|
|
SIR1
NAD-dependent protein deacetylase sirtuin-1 |
2 |
6 |
Small-scale |
0.624 | High |
|
|
UBP15
Ubiquitin carboxyl-terminal hydrolase 15 |
2 |
6 |
Small-scale |
0.624 | High |
|
|
DAZP2
DAZ-associated protein 2 |
2 |
2 |
Small-scale |
0.620 | High |
|
|
PRKN
E3 ubiquitin-protein ligase parkin |
1 |
19 |
High-throughput |
0.618 | High |
|
|
BCR
Breakpoint cluster region protein |
1 |
10 |
Small-scale |
0.618 | High |
|
|
BRAF
Serine/threonine-protein kinase B-raf |
1 |
13 |
Small-scale |
0.618 | High |
|
|
YAP1
Transcriptional coactivator YAP1 |
1 |
19 |
Small-scale |
0.618 | High |
|
|
UBC12
NEDD8-conjugating enzyme Ubc12 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
RL40
Ubiquitin-ribosomal protein eL40 fusion protein |
1 |
17 |
Small-scale |
0.618 | High |
|
|
UBC9
SUMO-conjugating enzyme UBC9 |
1 |
20 |
Small-scale |
0.618 | High |
|
|
HERC5
E3 ISG15--protein ligase HERC5 |
1 |
18 |
Small-scale |
0.618 | High |
|
|
SEMG2
Semenogelin-2 |
2 |
0 |
High-throughput |
0.602 | High |
|
|
SPART
Spartin |
2 |
10 |
Small-scale |
0.595 | High |
|
|
SYUA
Alpha-synuclein |
2 |
4 |
Small-scale |
0.594 | High |
|
|
FXL15
F-box/LRR-repeat protein 15 |
1 |
10 |
Small-scale |
0.589 | High |
|
|
GSK3B
Glycogen synthase kinase-3 beta |
2 |
3 |
Small-scale |
0.584 | High |
|
|
EZH2
Histone-lysine N-methyltransferase EZH2 |
2 |
5 |
Small-scale |
0.584 | High |
|
|
LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C |
1 |
6 |
Small-scale |
0.578 | High |
|
|
TOP2A
DNA topoisomerase 2-alpha |
1 |
4 |
Small-scale |
0.578 | High |
|
|
TTC3
E3 ubiquitin-protein ligase TTC3 |
1 |
20 |
Small-scale |
0.578 | High |
|
|
DSRAD
Double-stranded RNA-specific adenosine deaminase |
1 |
11 |
Small-scale |
0.578 | High |
|
|
TIF1B
Transcription intermediary factor 1-beta |
1 |
9 |
Small-scale |
0.578 | High |
|
|
ANM1
Protein arginine N-methyltransferase 1 |
1 |
6 |
Small-scale |
0.578 | High |
|
|
LMCD1
LIM and cysteine-rich domains protein 1 |
2 |
12 |
Small-scale |
0.576 | High |
|
|
LIGO2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2 |
2 |
4 |
High-throughput |
0.574 | High |
|
|
SYMM
Methionine--tRNA ligase, mitochondrial |
2 |
11 |
High-throughput |
0.574 | High |
|
|
XPO1
Exportin-1 |
1 |
13 |
Small-scale |
0.561 | High |
|
|
AXIN1
Axin-1 |
1 |
1 |
Small-scale |
0.561 | High |
|
|
ERBB2
Receptor tyrosine-protein kinase erbB-2 |
1 |
20 |
Small-scale |
0.561 | High |
|
|
ID3
DNA-binding protein inhibitor ID-3 |
1 |
3 |
Small-scale |
0.561 | High |
|
|
PDE4B
3',5'-cyclic-AMP phosphodiesterase 4B |
1 |
5 |
Small-scale |
0.561 | High |
|
|
AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 |
1 |
2 |
Small-scale |
0.561 | High |
|
|
AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 |
1 |
1 |
Small-scale |
0.561 | High |
|
|
MAVS
Mitochondrial antiviral-signaling protein |
1 |
11 |
Small-scale |
0.561 | High |
|
|
CNKR2
Connector enhancer of kinase suppressor of ras 2 |
1 |
7 |
Small-scale |
0.561 | High |
|
|
FUBP1
Far upstream element-binding protein 1 |
1 |
16 |
Small-scale |
0.561 | High |
|
|
RNF12
E3 ubiquitin-protein ligase RLIM |
1 |
9 |
Small-scale |
0.561 | High |
|
|
FBW1A
F-box/WD repeat-containing protein 1A |
1 |
6 |
Small-scale |
0.561 | High |
|
|
RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial |
2 |
7 |
High-throughput |
0.553 | High |
|
|
ATM
Serine-protein kinase ATM |
1 |
7 |
Small-scale |
0.536 | High |
|
|
KRIT1
Krev interaction trapped protein 1 |
1 |
14 |
High-throughput |
0.536 | High |
|
|
RSSA
Small ribosomal subunit protein uS2 |
1 |
5 |
High-throughput |
0.536 | High |
|
|
RS2
Small ribosomal subunit protein uS5 |
1 |
3 |
High-throughput |
0.536 | High |
|
|
RS19
Small ribosomal subunit protein eS19 |
1 |
4 |
High-throughput |
0.536 | High |
|
|
AOC2
Amine oxidase [copper-containing] 2 |
1 |
0 |
High-throughput |
0.513 | High |
|
|
STABP
STAM-binding protein |
1 |
0 |
Small-scale |
0.513 | High |
|
|
PAWR
PRKC apoptosis WT1 regulator protein |
1 |
0 |
High-throughput |
0.513 | High |
|
|
ACOX3
Peroxisomal acyl-coenzyme A oxidase 3 |
1 |
2 |
High-throughput |
0.508 | High |
|
|
FLNB
Filamin-B |
1 |
14 |
High-throughput |
0.508 | High |
|
|
RU17
U1 small nuclear ribonucleoprotein 70 kDa |
1 |
6 |
High-throughput |
0.508 | High |
|
|
DAB2
Disabled homolog 2 |
1 |
3 |
High-throughput |
0.508 | High |
|
|
LAPM5
Lysosomal-associated transmembrane protein 5 |
1 |
7 |
High-throughput |
0.508 | High |
|
|
ABRX2
BRISC complex subunit Abraxas 2 |
1 |
3 |
High-throughput |
0.508 | High |
|
|
SF3A2
Splicing factor 3A subunit 2 |
1 |
5 |
High-throughput |
0.508 | High |
|
|
RN111
E3 ubiquitin-protein ligase Arkadia |
1 |
7 |
High-throughput |
0.508 | High |
|
|
TXNIP
Thioredoxin-interacting protein |
1 |
20 |
High-throughput |
0.508 | High |
|
|
TNPO3
Transportin-3 |
1 |
16 |
High-throughput |
0.508 | High |
|
|
ITBP1
Integrin beta-1-binding protein 1 |
1 |
1 |
Small-scale |
0.501 | High |
|
|
PDE6A
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha |
1 |
5 |
High-throughput |
0.501 | High |
|
|
CADH3
Cadherin-3 |
1 |
2 |
High-throughput |
0.501 | High |
|
|
SCN1A
Sodium channel protein type 1 subunit alpha |
1 |
20 |
High-throughput |
0.501 | High |
|
|
RUNX2
Runt-related transcription factor 2 |
1 |
11 |
Small-scale |
0.501 | High |
|
|
SCN5A
Sodium channel protein type 5 subunit alpha |
1 |
20 |
High-throughput |
0.501 | High |
|
|
SCN9A
Sodium channel protein type 9 subunit alpha |
1 |
20 |
High-throughput |
0.501 | High |
|
|
AP2B
Transcription factor AP-2-beta |
1 |
1 |
High-throughput |
0.501 | High |
|
|
DVL2
Segment polarity protein dishevelled homolog DVL-2 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
SIX3
Homeobox protein SIX3 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
HSPB1
Heat shock protein beta-1 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
ADT2
ADP/ATP translocase 2 |
1 |
9 |
Small-scale |
0.479 | High |
|
|
PKHD1
Fibrocystin |
1 |
4 |
Small-scale |
0.479 | High |
|
|
ADT3
ADP/ATP translocase 3 |
1 |
9 |
Small-scale |
0.479 | High |
|
|
SKI
Ski oncogene |
1 |
4 |
Small-scale |
0.479 | High |
|
|
SKIL
Ski-like protein |
1 |
4 |
Small-scale |
0.479 | High |
|
|
ENPL
Endoplasmin |
1 |
13 |
High-throughput |
0.479 | High |
|
|
H2AX
Histone H2AX |
1 |
8 |
Small-scale |
0.479 | High |
|
|
TNR1B
Tumor necrosis factor receptor superfamily member 1B |
1 |
9 |
Small-scale |
0.479 | High |
|
|
NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1 |
1 |
10 |
Small-scale |
0.479 | High |
|
|
RL29
Large ribosomal subunit protein eL29 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
KIF11
Kinesin-like protein KIF11 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
ACTA
Actin, aortic smooth muscle |
1 |
5 |
Small-scale |
0.479 | High |
|
|
YBOX1
Y-box-binding protein 1 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
EFNB1
Ephrin-B1 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
ID2
DNA-binding protein inhibitor ID-2 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
ILF2
Interleukin enhancer-binding factor 2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
TRAF2
TNF receptor-associated factor 2 |
1 |
16 |
Small-scale |
0.479 | High |
|
|
PTC1
Protein patched homolog 1 |
1 |
14 |
Small-scale |
0.479 | High |
|
|
RUNX3
Runt-related transcription factor 3 |
1 |
11 |
Small-scale |
0.479 | High |
|
|
CASL
Enhancer of filamentation 1 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
HIF1A
Hypoxia-inducible factor 1-alpha |
1 |
2 |
Small-scale |
0.479 | High |
|
|
RN220
E3 ubiquitin-protein ligase RNF220 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TRI67
Tripartite motif-containing protein 67 |
1 |
11 |
High-throughput |
0.479 | High |
|
|
ENAH
Protein enabled homolog |
1 |
20 |
Small-scale |
0.479 | High |
|
|
GLIS3
Zinc finger protein GLIS3 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
SETD7
Histone-lysine N-methyltransferase SETD7 |
1 |
5 |
Small-scale |
0.479 | High |
|
|
RBM14
RNA-binding protein 14 |
1 |
12 |
Small-scale |
0.479 | High |
|
|
CCM2
Cerebral cavernous malformations 2 protein |
1 |
1 |
Small-scale |
0.479 | High |
|
|
MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle |
1 |
13 |
Small-scale |
0.479 | High |
|
|
HIPK2
Homeodomain-interacting protein kinase 2 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
MLXPL
Carbohydrate-responsive element-binding protein |
1 |
7 |
Small-scale |
0.479 | High |
|
|
PAR6A
Partitioning defective 6 homolog alpha |
1 |
13 |
Small-scale |
0.479 | High |
|
|
FMN2
Formin-2 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
UBP35
Ubiquitin carboxyl-terminal hydrolase 35 |
1 |
16 |
Small-scale |
0.479 | High |
|
|
PIAS3
E3 SUMO-protein ligase PIAS3 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
CALX
Calnexin |
1 |
5 |
High-throughput |
0.464 | High |
|
|
TFPI2
Tissue factor pathway inhibitor 2 |
1 |
4 |
High-throughput |
0.464 | High |
|
|
IDD
Integral membrane protein DGCR2/IDD |
1 |
11 |
High-throughput |
0.464 | High |
|
|
TM139
Transmembrane protein 139 |
1 |
1 |
High-throughput |
0.464 | High |
|
|
GCP60
Golgi resident protein GCP60 |
1 |
1 |
High-throughput |
0.464 | High |
|
|
SATB1
DNA-binding protein SATB1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
MD2L1
Mitotic spindle assembly checkpoint protein MAD2A |
1 |
0 |
Small-scale |
0.458 | High |
|
|
NADC
Nicotinate-nucleotide pyrophosphorylase [carboxylating] |
1 |
0 |
Small-scale |
0.458 | High |
|
|
INLR1
Interferon lambda receptor 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
ESF1
ESF1 homolog |
1 |
0 |
Small-scale |
0.458 | High |
|
|
COQ8A
Atypical kinase COQ8A, mitochondrial |
1 |
1 |
High-throughput |
0.457 | High |
|
|
ATPB
ATP synthase F(1) complex subunit beta, mitochondrial |
1 |
7 |
High-throughput |
0.457 | High |
|
|
DESM
Desmin |
1 |
3 |
High-throughput |
0.457 | High |
|
|
TNNI3
Troponin I, cardiac muscle |
1 |
1 |
High-throughput |
0.457 | High |
|
|
NEBU
Nebulin |
1 |
9 |
High-throughput |
0.457 | High |
|
|
EF1G
Elongation factor 1-gamma |
1 |
7 |
High-throughput |
0.457 | High |
|
|
TNNI2
Troponin I, fast skeletal muscle |
1 |
1 |
High-throughput |
0.457 | High |
|
|
RM19
Large ribosomal subunit protein bL19m |
1 |
2 |
High-throughput |
0.457 | High |
|
|
EIF3E
Eukaryotic translation initiation factor 3 subunit E |
1 |
3 |
High-throughput |
0.457 | High |
|
|
ACTS
Actin, alpha skeletal muscle |
1 |
3 |
High-throughput |
0.457 | High |
|
|
SQSTM
Sequestosome-1 |
1 |
6 |
High-throughput |
0.457 | High |
|
|
FHL2
Four and a half LIM domains protein 2 |
1 |
10 |
High-throughput |
0.457 | High |
|
|
FLNC
Filamin-C |
1 |
14 |
High-throughput |
0.457 | High |
|
|
MYPC3
Myosin-binding protein C, cardiac-type |
1 |
3 |
High-throughput |
0.457 | High |
|
|
DCAF6
DDB1- and CUL4-associated factor 6 |
1 |
10 |
High-throughput |
0.457 | High |
|
|
RM02
Large ribosomal subunit protein uL2m |
1 |
3 |
High-throughput |
0.457 | High |
|
|
CCAR1
Cell division cycle and apoptosis regulator protein 1 |
1 |
3 |
High-throughput |
0.457 | High |
|
|
TITIN
Titin |
1 |
3 |
High-throughput |
0.457 | High |
|
|
UXT
Protein UXT |
1 |
1 |
High-throughput |
0.457 | High |
|
|
TELT
Telethonin |
1 |
0 |
High-throughput |
0.438 | High |
|
|
TNNT1
Troponin T, slow skeletal muscle |
1 |
0 |
High-throughput |
0.438 | High |
|
|
MYOZ1
Myozenin-1 |
1 |
0 |
High-throughput |
0.438 | High |
|
|
GMEB1
Glucocorticoid modulatory element-binding protein 1 |
1 |
0 |
High-throughput |
0.438 | High |
|
|
RT22
Small ribosomal subunit protein mS22 |
1 |
1 |
Small-scale |
0.437 | High |
|
|
DJC10
DnaJ homolog subfamily C member 10 |
1 |
9 |
Small-scale |
0.437 | High |
|
|
KCD12
BTB/POZ domain-containing protein KCTD12 |
1 |
8 |
Small-scale |
0.437 | High |
|
|
RT07
Small ribosomal subunit protein uS7m |
1 |
5 |
Small-scale |
0.437 | High |
|
|
RT23
Small ribosomal subunit protein mS23 |
1 |
1 |
Small-scale |
0.437 | High |
|
|
RRP8
Ribosomal RNA-processing protein 8 |
1 |
0 |
High-throughput |
0.426 | High |
|
|
TF2LY
Homeobox protein TGIF2LY |
1 |
0 |
High-throughput |
0.426 | High |
|
|
NEBL
Nebulette |
1 |
14 |
High-throughput |
0.417 | High |
|
|
ECHM
Enoyl-CoA hydratase, mitochondrial |
1 |
6 |
High-throughput |
0.417 | High |
|
|
DSCR9
Down syndrome critical region protein 9 |
1 |
1 |
High-throughput |
0.417 | High |
|
|
NOMO1
BOS complex subunit NOMO1 |
1 |
1 |
High-throughput |
0.417 | High |
|
|
EFGM
Elongation factor G, mitochondrial |
1 |
11 |
High-throughput |
0.417 | High |
|
|
LATS1
Serine/threonine-protein kinase LATS1 |
1 |
18 |
Small-scale |
0.408 | High |
|
|
C144B
Putative coiled-coil domain-containing protein 144B |
1 |
3 |
High-throughput |
0.407 | High |
|
|
EFHC1
EF-hand domain-containing protein 1 |
1 |
0 |
High-throughput |
0.261 | Low |
|
|
RT31
Small ribosomal subunit protein mS31 |
1 |
0 |
Small-scale |
0.249 | Low |
|
|
NDUA1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 |
1 |
0 |
High-throughput |
0.238 | Low |
|
|
RM41
Large ribosomal subunit protein mL41 |
1 |
0 |
High-throughput |
0.238 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
