Interactor 1: XRN1 (Q8IZH2)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)
Gene: XRN1

Interactor 2: XRN1 (Q8IZH2)
5'-3' exoribonuclease 1 (EC 3.1.13.-) (Strand-exchange protein 1 homolog)
Gene: XRN1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 31839598
Identification Methods cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains SH3_12~XRN1_D1, SH3_12~XRN1_D2_D3, SH3_12~XRN_N, XRN1_D1~XRN1_D2_D3, XRN1_D1~XRN_M, XRN1_D1~XRN_N, XRN1_D2_D3~XRN1_D2_D3, XRN1_D2_D3~XRN_M, XRN_M~XRN_M, XRN_M~XRN_N, XRN_N~XRN_N
Common GO terms GO:0000932 - P-body
GO:0000956 - nuclear-transcribed mRNA catabolic process
GO:0002151 - G-quadruplex RNA binding
GO:0003723 - RNA binding
GO:0004534 - 5'-3' RNA exonuclease activity
and 16 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 1706
Hs

1 1706
+ Sc
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025