HitPredict

Interactor 1: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Interactor 2: FBRS (Q9HAH7)
Probable fibrosin-1
Gene: FBRS

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.50	0.638

Property	Details
Experiments	24981860, 28514442, 27705803, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 350 Hs			1 460
+	Hs
		718208 BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		718429 PCGF2_HUMAN (117-350): 6.32e-65: 211: 33.47		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1108544 PCGF3_HUMAN (120-341): 3.31e-65: 208: 34.44		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1311545 PCGF1_HUMAN (119-347): 3.16e-60: 196: 34.91		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1197591 PCGF5_HUMAN (117-344): 6.93e-50: 169: 31.73		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		1304115 RING2_HUMAN (85-303): 3.51e-32: 124: 14.49		FBRS_HUMAN (1-460): 0: 527: 100.00
+	Hs
		111280 RING2_HUMAN (85-303): 3.51e-32: 124: 14.49		J3KNZ9_HUMAN (1-460): 2.78e-175: 518: 100.00
+	Hs
		1316706 PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00		FBSL_HUMAN (2-327): 3.71e-103: 332: 35.31
+	Hs
		1264229 PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00		AUTS2_HUMAN (1-283): 2.39e-90: 300: 43.62
+	Hs
		1108546 PCGF3_HUMAN (120-341): 3.31e-65: 208: 34.44		FBSL_HUMAN (2-327): 3.71e-103: 332: 35.31
+	Hs
		1108524 PCGF3_HUMAN (120-341): 3.31e-65: 208: 34.44		AUTS2_HUMAN (1-283): 2.39e-90: 300: 43.62
+	Mm
		393 PCGF3_MOUSE (120-341): 1.16e-63: 204: 34.58		AUTS2_MOUSE (1-270): 6.05e-90: 299: 44.91
+	Hs
		1197593 PCGF5_HUMAN (117-344): 6.93e-50: 169: 31.73		FBSL_HUMAN (2-327): 3.71e-103: 332: 35.31
+	Hs
		1197576 PCGF5_HUMAN (117-344): 6.93e-50: 169: 31.73		AUTS2_HUMAN (1-283): 2.39e-90: 300: 43.62
+	Hs
		1304118 RING2_HUMAN (85-303): 3.51e-32: 124: 14.49		FBSL_HUMAN (2-327): 3.71e-103: 332: 35.31
+	Hs
		1264228 RING2_HUMAN (85-303): 3.51e-32: 124: 14.49		AUTS2_HUMAN (1-283): 2.39e-90: 300: 43.62
+	Mm
		397 RING2_MOUSE (85-303): 2.38e-32: 125: 14.49		AUTS2_MOUSE (1-270): 6.05e-90: 299: 44.91
+	Mm
		1161097 PCGF3_MOUSE (120-341): 1.16e-63: 204: 34.58		Q6PED7_MOUSE (74-270): 7.79e-62: 213: 43.13
+	Mm
		1112807 PCGF5_MOUSE (117-344): 9.38e-51: 171: 32.13		Q6PED7_MOUSE (74-270): 7.79e-62: 213: 43.13
+	Mm
		1161099 RING2_MOUSE (85-303): 2.38e-32: 125: 14.49		Q6PED7_MOUSE (74-270): 7.79e-62: 213: 43.13