Protein: VINEX
Vinexin (SH3-containing adapter molecule 1) (SCAM-1) (Sorbin and SH3 domain-containing protein 3)

Gene: VINEX, SORBS3
Organism: Homo sapiens
Interactions: 204
UniProt ID: O60504

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000165 - MAPK cascade
GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250297

DLG5
Disks large homolog 5

3

18

Small-scale

0.874

High

250312

CPNE2
Copine-2

3

4

High-throughput

0.871

High

250336

SH24A
SH2 domain-containing protein 4A

3

20

High-throughput

0.871

High

155147

SOCS7
Suppressor of cytokine signaling 7

3

17

Small-scale

0.864

High

250214

AKT2
RAC-beta serine/threonine-protein kinase

2

10

High-throughput

0.783

High

250220

CDN2C
Cyclin-dependent kinase 4 inhibitor C

2

20

High-throughput

0.783

High

250265

TENS2
Tensin-2

2

10

High-throughput

0.783

High

250266

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

19

High-throughput

0.783

High

250289

SESQ1
Sesquipedalian-1

2

20

High-throughput

0.783

High

250294

IKBD
NF-kappa-B inhibitor delta

2

10

High-throughput

0.783

High

250323

CPNE1
Copine-1

2

3

High-throughput

0.783

High

250349

ABI2
Abl interactor 2

2

20

High-throughput

0.783

High

250219

ABL2
Tyrosine-protein kinase ABL2

2

20

High-throughput

0.776

High

250271

ANR54
Ankyrin repeat domain-containing protein 54

2

14

High-throughput

0.776

High

250320

ARAP1
Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1

2

20

High-throughput

0.776

High

250341

TENS1
Tensin-1

2

10

High-throughput

0.776

High

250352

SPN90
NCK-interacting protein with SH3 domain

1

5

High-throughput

0.740

High

250195

ABL1
Tyrosine-protein kinase ABL1

1

20

Small-scale

0.724

High

250232

HNRPK
Heterogeneous nuclear ribonucleoprotein K

4

10

High-throughput

0.705

High

250324

RTKN
Rhotekin

1

3

Small-scale

0.700

High

250283

CPNE8
Copine-8

2

3

High-throughput

0.700

High

211964

EFS
Embryonal Fyn-associated substrate

1

20

High-throughput

0.698

High

250181

VINEX
Vinexin

1

17

High-throughput

0.698

High

250242

PAK2
Serine/threonine-protein kinase PAK 2

3

20

Small-scale

0.689

High

250216

TRI23
E3 ubiquitin-protein ligase TRIM23

3

4

High-throughput

0.675

High

250316

MY15B
Unconventional myosin-XVB

1

14

High-throughput

0.665

High

250292

IQUB
IQ motif and ubiquitin-like domain-containing protein

2

0

High-throughput

0.655

High

187831

EIF3H
Eukaryotic translation initiation factor 3 subunit H

3

10

High-throughput

0.654

High

250205

VINC
Vinculin

3

12

High-throughput

0.653

High

187232

SHIP2
Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2

1

20

Small-scale

0.653

High

250300

WIPF2
WAS/WASL-interacting protein family member 2

3

20

High-throughput

0.647

High

250362

NOTC3
Neurogenic locus notch homolog protein 3

1

7

Small-scale

0.647

High

250262

SYVM
Valine--tRNA ligase, mitochondrial

3

0

High-throughput

0.646

High

133611

WASL
Actin nucleation-promoting factor WASL

3

20

Small-scale

0.643

High

250203

NCK1
SH2/SH3 adapter protein NCK1

1

20

High-throughput

0.621

High

250305

ANS1A
Ankyrin repeat and SAM domain-containing protein 1A

1

19

High-throughput

0.621

High

250331

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

20

High-throughput

0.621

High

250357

UBQL2
Ubiquilin-2

1

8

High-throughput

0.618

High

63156

VP37C
Vacuolar protein sorting-associated protein 37C

3

20

High-throughput

0.616

High

169345

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

7

High-throughput

0.606

High

216153

MTG8R
Protein CBFA2T2

2

2

High-throughput

0.606

High

250185

LIPA3
Liprin-alpha-3

2

8

High-throughput

0.606

High

250188

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

10

High-throughput

0.606

High

250189

RA51D
DNA repair protein RAD51 homolog 4

2

1

High-throughput

0.606

High

250210

DDX6
Probable ATP-dependent RNA helicase DDX6

2

10

High-throughput

0.606

High

250218

TXLNA
Alpha-taxilin

2

18

High-throughput

0.606

High

250225

CCNH
Cyclin-H

2

5

High-throughput

0.606

High

250226

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

8

High-throughput

0.606

High

250228

GEM
GTP-binding protein GEM

2

11

High-throughput

0.606

High

250238

MTG8
Protein CBFA2T1

2

2

High-throughput

0.606

High

250244

RIN1
Ras and Rab interactor 1

2

20

High-throughput

0.606

High

250247

TEAD4
Transcriptional enhancer factor TEF-3

2

1

High-throughput

0.606

High

250248

NAB2
NGFI-A-binding protein 2

2

1

High-throughput

0.606

High

250249

CCDC6
Coiled-coil domain-containing protein 6

2

20

High-throughput

0.606

High

250252

CCD57
Coiled-coil domain-containing protein 57

2

15

High-throughput

0.606

High

250254

PKHN1
Pleckstrin homology domain-containing family N member 1

2

2

High-throughput

0.606

High

250268

C102B
Coiled-coil domain-containing protein 102B

2

11

High-throughput

0.606

High

250272

PPR18
Phostensin

2

20

High-throughput

0.606

High

250273

FXL19
F-box/LRR-repeat protein 19

2

1

High-throughput

0.606

High

250285

CHERP
Calcium homeostasis endoplasmic reticulum protein

2

12

High-throughput

0.606

High

250286

PPIL6
Probable inactive peptidyl-prolyl cis-trans isomerase-like 6

2

2

High-throughput

0.606

High

250291

TEANC
Transcription elongation factor A N-terminal and central domain-containing protein

2

2

High-throughput

0.606

High

250296

CCHCR
Coiled-coil alpha-helical rod protein 1

2

12

High-throughput

0.606

High

250309

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

20

High-throughput

0.606

High

250314

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

2

1

High-throughput

0.606

High

250319

AP4AT
AP-4 complex accessory subunit Tepsin

2

1

High-throughput

0.606

High

250322

PNMA5
Paraneoplastic antigen-like protein 5

2

5

High-throughput

0.606

High

250325

EFC4B
EF-hand calcium-binding domain-containing protein 4B

2

7

High-throughput

0.606

High

250332

TSG10
Testis-specific gene 10 protein

2

19

High-throughput

0.606

High

250333

SETD5
Histone-lysine N-methyltransferase SETD5

2

2

High-throughput

0.606

High

250337

SYP2L
Synaptopodin 2-like protein

2

19

High-throughput

0.606

High

250338

COG4
Conserved oligomeric Golgi complex subunit 4

2

1

High-throughput

0.606

High

250343

NEK6
Serine/threonine-protein kinase Nek6

2

16

High-throughput

0.606

High

250346

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

2

1

High-throughput

0.606

High

250358

NRBP
Nuclear receptor-binding protein

2

1

High-throughput

0.606

High

250360

CDC23
Cell division cycle protein 23 homolog

2

5

High-throughput

0.606

High

250361

CCNL1
Cyclin-L1

2

5

High-throughput

0.606

High

250279

K0408
Uncharacterized protein KIAA0408

2

2

High-throughput

0.590

High

180185

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

0

High-throughput

0.580

High

210221

PHF1
PHD finger protein 1

2

0

High-throughput

0.580

High

217022

MS18B
Protein Mis18-beta

2

0

High-throughput

0.580

High

250193

DRC4
Dynein regulatory complex subunit 4

2

0

High-throughput

0.580

High

250201

GYS1
Glycogen [starch] synthase, muscle

2

0

High-throughput

0.580

High

250221

SYQ
Glutamine--tRNA ligase

2

0

High-throughput

0.580

High

250240

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

0

High-throughput

0.580

High

250253

T10IP
Testis-specific protein 10-interacting protein

2

0

High-throughput

0.580

High

250258

AKIR2
Akirin-2

2

0

High-throughput

0.580

High

250280

ATOSB
Atos homolog protein B

2

0

High-throughput

0.580

High

250308

GPKOW
G-patch domain and KOW motifs-containing protein

2

0

High-throughput

0.580

High

250311

ADAT3
Probable inactive tRNA-specific adenosine deaminase-like protein 3

2

0

High-throughput

0.580

High

250315

ZN414
Zinc finger protein 414

2

0

High-throughput

0.580

High

250329

SCNM1
Sodium channel modifier 1

2

0

High-throughput

0.580

High

250340

ROP1A
Ropporin-1A

2

0

High-throughput

0.580

High

250347

AIRIM
AFG2-interacting ribosome maturation factor

2

0

High-throughput

0.580

High

250350

FA53C
Protein FAM53C

2

0

High-throughput

0.580

High

250351

SPG21
Maspardin

2

0

High-throughput

0.580

High

250235

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

20

High-throughput

0.575

High

250270

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.575

High

250321

ARHGH
Rho guanine nucleotide exchange factor 17

1

19

High-throughput

0.575

High

250274

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

2

1

High-throughput

0.574

High

250345

TB22B
TBC1 domain family member 22B

2

1

High-throughput

0.573

High

180131

ZBT7B
Zinc finger and BTB domain-containing protein 7B

1

9

High-throughput

0.573

High

250202

TRI27
Zinc finger protein RFP

1

5

High-throughput

0.573

High

250301

TRI41
E3 ubiquitin-protein ligase TRIM41

1

5

High-throughput

0.573

High

250326

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

4

High-throughput

0.573

High

250339

VP37B
Vacuolar protein sorting-associated protein 37B

1

20

High-throughput

0.573

High

250355

PAK5
Serine/threonine-protein kinase PAK 5

1

20

High-throughput

0.573

High

250212

MK01
Mitogen-activated protein kinase 1

1

1

Small-scale

0.561

High

250183

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

2

1

High-throughput

0.553

High

250192

GPAN1
G patch domain and ankyrin repeat-containing protein 1

2

15

High-throughput

0.553

High

250261

EFHC1
EF-hand domain-containing protein 1

2

1

High-throughput

0.553

High

250293

CTSR1
Cation channel sperm-associated protein 1

2

8

High-throughput

0.553

High

250327

KIFC3
Kinesin-like protein KIFC3

2

9

High-throughput

0.553

High

250334

SRCN1
SRC kinase signaling inhibitor 1

1

6

Small-scale

0.552

High

250288

SAXO1
Stabilizer of axonemal microtubules 1

1

0

High-throughput

0.549

High

250344

ZC4H2
Zinc finger C4H2 domain-containing protein

1

0

High-throughput

0.549

High

159434

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

20

High-throughput

0.541

High

250194

ZBED1
E3 SUMO-protein ligase ZBED1

1

1

High-throughput

0.541

High

250199

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.541

High

250209

ZBT25
Zinc finger and BTB domain-containing protein 25

1

9

High-throughput

0.541

High

250217

RBMX
RNA-binding motif protein, X chromosome

1

4

High-throughput

0.541

High

250224

FXR1
RNA-binding protein FXR1

1

2

High-throughput

0.541

High

250243

CBLB
E3 ubiquitin-protein ligase CBL-B

1

20

High-throughput

0.541

High

250263

SKT
Sickle tail protein homolog

1

6

High-throughput

0.541

High

250290

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

8

High-throughput

0.541

High

250306

DDX17
Probable ATP-dependent RNA helicase DDX17

1

4

High-throughput

0.541

High

250342

ARNT2
Aryl hydrocarbon receptor nuclear translocator 2

1

1

High-throughput

0.541

High

215885

SYNJ1
Synaptojanin-1

1

20

High-throughput

0.536

High

250182

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.536

High

250184

CCD22
Coiled-coil domain-containing protein 22

1

8

High-throughput

0.536

High

250187

KTNA1
Katanin p60 ATPase-containing subunit A1

1

8

High-throughput

0.536

High

250196

RASK
GTPase KRas

1

20

High-throughput

0.536

High

250197

ALBU
Albumin

1

2

High-throughput

0.536

High

250213

AA1R
Adenosine receptor A1

1

1

High-throughput

0.536

High

250229

AFAD
Afadin

1

20

High-throughput

0.536

High

250234

ACTS
Actin, alpha skeletal muscle

1

20

High-throughput

0.536

High

250295

RIN3
Ras and Rab interactor 3

1

20

High-throughput

0.536

High

250298

MICA1
[F-actin]-monooxygenase MICAL1

1

20

High-throughput

0.536

High

250317

KLH15
Kelch-like protein 15

1

4

High-throughput

0.536

High

3271

A0A0S2Z4D7
NCK adaptor protein 1 isoform 2

1

20

High-throughput

0.528

High

171960

HNRDL
Heterogeneous nuclear ribonucleoprotein D-like

1

8

High-throughput

0.515

High

250245

SAFB2
Scaffold attachment factor B2

1

9

Small-scale

0.515

High

250330

B2L13
Bcl-2-like protein 13

1

1

High-throughput

0.515

High

250363

WASF2
Actin-binding protein WASF2

1

20

Small-scale

0.515

High

250255

Q49AR9
ANKS1A protein

1

20

High-throughput

0.515

High

250282

PHLB1
Pleckstrin homology-like domain family B member 1

1

20

High-throughput

0.514

High

250231

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.513

High

250275

PARM1
Prostate androgen-regulated mucin-like protein 1

1

0

High-throughput

0.513

High

250277

UBR3
E3 ubiquitin-protein ligase UBR3

1

0

High-throughput

0.513

High

250310

ARK2N
Protein ARK2N

1

0

High-throughput

0.513

High

160952

ADA10
Disintegrin and metalloproteinase domain-containing protein 10

1

18

Small-scale

0.501

High

250190

FLOT1
Flotillin-1

1

7

Small-scale

0.501

High

250222

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

4

Small-scale

0.501

High

250276

ATL4
ADAMTS-like protein 4

1

1

High-throughput

0.494

High

250259

KLH26
Kelch-like protein 26

1

4

High-throughput

0.489

High

250354

NHSL3
NHS-like protein 3

1

20

High-throughput

0.489

High

250281

CPEB2
Cytoplasmic polyadenylation element-binding protein 2

1

4

Small-scale

0.481

High

250302

PIBF1
Progesterone-induced-blocking factor 1

1

1

High-throughput

0.481

High

250304

TSC1
Hamartin

1

20

High-throughput

0.481

High

250318

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

1

High-throughput

0.481

High

250186

TULP3
Tubby-related protein 3

1

3

High-throughput

0.479

High

250191

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.479

High

250200

RARG
Retinoic acid receptor gamma

1

12

Small-scale

0.479

High

250204

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

6

Small-scale

0.479

High

250207

CBL
E3 ubiquitin-protein ligase CBL

1

20

Small-scale

0.479

High

250223

CDK7
Cyclin-dependent kinase 7

1

1

High-throughput

0.479

High

250233

EF1A1
Elongation factor 1-alpha 1

1

3

High-throughput

0.479

High

250236

TF65
Transcription factor p65

1

6

High-throughput

0.479

High

250237

EF1A2
Elongation factor 1-alpha 2

1

3

High-throughput

0.479

High

250241

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

20

High-throughput

0.479

High

250250

E2F4
Transcription factor E2F4

1

1

High-throughput

0.479

High

250267

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.479

High

250278

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

250303

WASF1
Actin-binding protein WASF1

1

20

Small-scale

0.479

High

250356

ZRAN1
Ubiquitin thioesterase ZRANB1

1

12

High-throughput

0.479

High

250256

Q4G0R1
PIBF1 protein

1

1

High-throughput

0.470

High

250260

NHSL2
NHS-like protein 2

1

19

High-throughput

0.470

High

250269

Q6IB98
Eukaryotic translation initiation factor 3 subunit H

1

10

High-throughput

0.470

High

250211

1433T
14-3-3 protein theta

1

20

High-throughput

0.445

High

250215

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.445

High

250299

SHRM3
Protein Shroom3

1

18

High-throughput

0.445

High

250307

CSN5
COP9 signalosome complex subunit 5

1

12

High-throughput

0.445

High

250198

SYPH
Synaptophysin

1

1

Small-scale

0.437

High

250264

OTUD1
OTU domain-containing protein 1

1

12

High-throughput

0.437

High

250353

DLGP2
Disks large-associated protein 2

1

16

High-throughput

0.437

High

250206

TNNI1
Troponin I, slow skeletal muscle

1

0

High-throughput

0.426

High

250227

PGTB2
Geranylgeranyl transferase type-2 subunit beta

1

0

High-throughput

0.426

High

4750

A0A1B0GTN4
DLG associated protein 2

1

16

High-throughput

0.407

High

141967

FCN1
Ficolin-1

1

1

High-throughput

0.407

High

183895

S22A2
Solute carrier family 22 member 2

1

2

High-throughput

0.407

High

250208

GLRA1
Glycine receptor subunit alpha-1

2

0

High-throughput

0.316

High

250230

DPOE2
DNA polymerase epsilon subunit 2

2

0

High-throughput

0.316

High

250251

INSC
Protein inscuteable homolog

2

0

High-throughput

0.316

High

250257

ZC21C
Zinc finger C2HC domain-containing protein 1C

2

0

High-throughput

0.316

High

250284

Q8IVT4
Hypothetical MGC50722

2

0

High-throughput

0.316

High

250287

CF206
Cilia- and flagella-associated protein 206

2

0

High-throughput

0.316

High

250313

CC120
Coiled-coil domain-containing protein 120

2

0

High-throughput

0.316

High

250328

FND11
Fibronectin type III domain-containing protein 11

2

0

High-throughput

0.316

High

250335

ENKD1
Enkurin domain-containing protein 1

2

0

High-throughput

0.316

High

250359

OSGI1
Oxidative stress-induced growth inhibitor 1

2

0

High-throughput

0.316

High

250246

DIP2A
Disco-interacting protein 2 homolog A

1

0

High-throughput

0.299

High

250348

S39A1
Zinc transporter ZIP1

1

0

High-throughput

0.269

Low

250239

SIA4A
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025