HitPredict

Interactor 1: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Interactor 2: NLE1 (Q9NVX2)
Notchless protein homolog 1
Gene: NLE1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005730 - nucleolus
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 293 Hs			1 485
+	Hs
		1281369 MK67I_HUMAN (1-293): 8.07e-53: 176: 100.00		FBXW7_HUMAN (6-352): 2.75e-69: 236: 21.41
+	Sc
		630883 NOP15_YEAST (14-185): 3.16e-37: 133: 30.64		NLE1_YEAST (2-314): 3.8e-78: 254: 19.61
+	Hs
		1281457 PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96		FBXW7_HUMAN (6-352): 2.75e-69: 236: 21.41
+	Hs
		903196 PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Hs
		516438 PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92
+	Hs
		903585 PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96		WDR5_HUMAN (2-231): 8.42e-54: 185: 19.92