Protein: SPPL3
Signal peptide peptidase-like 3 (SPP-like 3) (EC 3.4.23.-) (Intramembrane protease 2) (IMP-2) (Presenilin homologous protein 1) (PSH1) (Presenilin-like protein 4)

Gene: SPPL3
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q8TCT6

Gene Ontology (top 5):
GO:0005791 - rough endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0006465 - signal peptide processing
GO:0007204 - positive regulation of cytosolic calcium ion concentration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

802360

5HT3A
5-hydroxytryptamine receptor 3A

2

10

High-throughput

0.628

High

989633

ACHD
Acetylcholine receptor subunit delta

2

8

High-throughput

0.628

High

1083468

C3AR
C3a anaphylatoxin chemotactic receptor

2

3

High-throughput

0.628

High

1202616

S22AG
Solute carrier family 22 member 16

2

3

High-throughput

0.628

High

1224315

AGRG5
Adhesion G-protein coupled receptor G5

2

4

High-throughput

0.628

High

1253829

S39A8
Metal cation symporter ZIP8

2

5

High-throughput

0.628

High

1253830

YIPF3
Protein YIPF3

2

1

High-throughput

0.628

High

1253837

P2RX2
P2X purinoceptor 2

2

1

High-throughput

0.628

High

801619

S15A1
Solute carrier family 15 member 1

2

0

High-throughput

0.602

High

1067928

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.602

High

1078119

AAAT
Neutral amino acid transporter B(0)

2

0

High-throughput

0.602

High

1202844

TPRA1
Transmembrane protein adipocyte-associated 1

2

0

High-throughput

0.602

High

1253825

SPP2B
Signal peptide peptidase-like 2B

2

0

High-throughput

0.602

High

1253826

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

0

High-throughput

0.602

High

1253833

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

2

0

High-throughput

0.602

High

868007

VMAT1
Chromaffin granule amine transporter

2

4

High-throughput

0.574

High

126627

P2Y10
Putative P2Y purinoceptor 10

1

6

High-throughput

0.536

High

156884

FFAR1
Free fatty acid receptor 1

1

5

High-throughput

0.536

High

172138

GP182
G-protein coupled receptor 182

1

5

High-throughput

0.536

High

570865

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

8

High-throughput

0.536

High

600804

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

5

High-throughput

0.536

High

674060

V2R
Vasopressin V2 receptor

1

1

High-throughput

0.536

High

686336

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

1

High-throughput

0.536

High

798538

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

6

High-throughput

0.536

High

813961

GPR12
G-protein coupled receptor 12

1

2

High-throughput

0.536

High

833278

TMEDA
Transmembrane emp24 domain-containing protein 10

1

5

High-throughput

0.536

High

849690

CCR6
C-C chemokine receptor type 6

1

4

High-throughput

0.536

High

957440

IDD
Integral membrane protein DGCR2/IDD

1

2

High-throughput

0.536

High

1031026

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

5

High-throughput

0.536

High

1156872

NIPA3
Magnesium transporter NIPA3

1

2

High-throughput

0.536

High

1236926

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.536

High

1252584

S7A14
Solute carrier family 7 member 14

1

1

High-throughput

0.536

High

1253827

CREL1
Protein disulfide isomerase CRELD1

1

1

High-throughput

0.536

High

1253831

S22A4
Solute carrier family 22 member 4

1

3

High-throughput

0.536

High

1253832

TSN10
Tetraspanin-10

1

1

High-throughput

0.536

High

1253835

AT133
Polyamine-transporting ATPase 13A3

1

8

High-throughput

0.536

High

1253841

GPR45
Probable G-protein coupled receptor 45

1

1

High-throughput

0.536

High

353079

IL2RA
Interleukin-2 receptor subunit alpha

1

0

High-throughput

0.513

High

574390

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.513

High

575117

RL7
Large ribosomal subunit protein uL30

1

0

High-throughput

0.513

High

781090

OPRX
Nociceptin receptor

1

0

High-throughput

0.513

High

913647

RL7A
Large ribosomal subunit protein eL8

1

0

High-throughput

0.513

High

923437

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.513

High

962232

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

0

High-throughput

0.513

High

989863

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.513

High

1253828

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

1253838

SC5A6
Sodium-dependent multivitamin transporter

1

0

High-throughput

0.513

High

1217711

S22A9
Organic anion transporter 7

1

3

High-throughput

0.489

High

1253834

TM231
Transmembrane protein 231

1

1

High-throughput

0.489

High

1253836

TBA8
Tubulin alpha-8 chain

1

0

High-throughput

0.279

Low

1253839

SL9A8
Sodium/hydrogen exchanger 8

1

0

High-throughput

0.279

Low

1253840

UTP11
Probable U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024