HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28794006, 35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0035019 - somatic stem cell population maintenance GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1426 Hs			1 317
+	Hs
		131701 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57
+	Hs
		131745 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		131707 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		131680 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		SOX15_HUMAN (13-118): 1.78e-31: 119: 66.04
+	Hs
		818550 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818207 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		727221 NU214_HUMAN (28-979): 7.89e-14: 79: 9.22		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818458 TARA_HUMAN (396-1426): 7.45e-13: 75.9: 5.34		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818382 MINT_HUMAN (2-1423): 1.23e-12: 75.6: 7.47		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		818049 NCOA6_HUMAN (1-1013): 5.94e-12: 72.9: 7.69		SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00
+	Hs
		727814 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX5_HUMAN (2-127): 7.91e-43: 158: 41.27
+	Hs
		996722 ANR11_HUMAN (201-1034): 8.62e-25: 115: 11.85		SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68
+	Hs
		818841 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57
+	Hs
		1332326 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19
+	Hs
		1300971 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		CIC_HUMAN (3-272): 8.9e-33: 130: 22.26
+	Hs
		881831 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX10_HUMAN (28-219): 8.75e-34: 130: 35.42
+	Hs
		1311936 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX7_HUMAN (23-299): 8.76e-34: 129: 27.03
+	Hs
		727934 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		SOX6_HUMAN (29-244): 2.42e-29: 120: 23.61
+	Hs
		818804 NCOA6_HUMAN (1-1013): 5.94e-12: 72.9: 7.69		SOX9_HUMAN (28-260): 2.6e-37: 140: 27.57
+	Hs
		1057795 NCOA6_HUMAN (1-1013): 5.94e-12: 72.9: 7.69		SOX17_HUMAN (7-260): 1.35e-34: 132: 28.19