Protein: ITCH
E3 ubiquitin-protein ligase Itchy homolog (Itch) (EC 2.3.2.26) (Atrophin-1-interacting protein 4) (AIP4) (HECT-type E3 ubiquitin transferase Itchy homolog) (NFE2-associated polypeptide 1) (NAPP1)

Gene: ITCH
Organism: Homo sapiens
Interactions: 365
UniProt ID: Q96J02

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0002669 - positive regulation of T cell anergy
GO:0002870 - T cell anergy
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

996004

UB2L3
Ubiquitin-conjugating enzyme E2 L3

21

20

Small-scale

0.989

High

1394585

ITCH
E3 ubiquitin-protein ligase Itchy homolog

18

14

Small-scale

0.987

High

508443

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

8

20

Small-scale

0.961

High

982287

UB2D2
Ubiquitin-conjugating enzyme E2 D2

6

20

Small-scale

0.942

High

906748

UB2D1
Ubiquitin-conjugating enzyme E2 D1

5

20

Small-scale

0.919

High

957169

UB2D3
Ubiquitin-conjugating enzyme E2 D3

4

20

Small-scale

0.882

High

292861

GRAP2
GRB2-related adapter protein 2

3

17

High-throughput

0.861

High

1394608

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

3

15

High-throughput

0.861

High

1394586

UB2E2
Ubiquitin-conjugating enzyme E2 E2

3

20

Small-scale

0.858

High

883316

UB2R1
Ubiquitin-conjugating enzyme E2 R1

3

20

Small-scale

0.845

High

909375

UB2E1
Ubiquitin-conjugating enzyme E2 E1

3

20

Small-scale

0.845

High

1394607

TOLIP
Toll-interacting protein

3

2

High-throughput

0.839

High

578533

BRAF
Serine/threonine-protein kinase B-raf

2

13

Small-scale

0.819

High

1115588

ASPP2
Apoptosis-stimulating of p53 protein 2

2

13

Small-scale

0.819

High

1359826

RASF5
Ras association domain-containing protein 5

2

4

Small-scale

0.806

High

1368289

STAM1
Signal transducing adapter molecule 1

2

20

Small-scale

0.806

High

957648

UBE2K
Ubiquitin-conjugating enzyme E2 K

2

20

Small-scale

0.778

High

970223

UB2G1
Ubiquitin-conjugating enzyme E2 G1

2

20

Small-scale

0.778

High

168559

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

2

20

High-throughput

0.768

High

862377

YAP1
Transcriptional coactivator YAP1

2

19

Small-scale

0.754

High

1394630

WWOX
WW domain-containing oxidoreductase

2

1

Small-scale

0.754

High

1394631

PD1L1
Programmed cell death 1 ligand 1

2

7

Small-scale

0.754

High

1394610

TXNIP
Thioredoxin-interacting protein

7

20

Small-scale

0.752

High

1327833

ARRD1
Arrestin domain-containing protein 1

8

20

Small-scale

0.751

High

1322302

SPART
Spartin

8

10

Small-scale

0.751

High

186788

P73
Tumor protein p73

6

15

Small-scale

0.742

High

193037

CFLAR
CASP8 and FADD-like apoptosis regulator

8

3

Small-scale

0.741

High

1384104

ARRD3
Arrestin domain-containing protein 3

6

20

Small-scale

0.739

High

1394609

P63
Tumor protein 63

6

15

Small-scale

0.738

High

1394597

SH3G3
Endophilin-A3

2

12

High-throughput

0.737

High

1394643

RNF11
RING finger protein 11

6

15

Small-scale

0.737

High

349204

LATS1
Serine/threonine-protein kinase LATS1

6

18

Small-scale

0.736

High

401310

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

16

Small-scale

0.724

High

440678

FYN
Tyrosine-protein kinase Fyn

1

14

Small-scale

0.724

High

1154155

ITSN1
Intersectin-1

1

9

Small-scale

0.724

High

1155174

EREP1
Endosomal transmembrane epsin interactor 1

5

15

Small-scale

0.718

High

1394596

SH3G2
Endophilin-A1

4

12

Small-scale

0.706

High

1160249

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

4

20

High-throughput

0.703

High

956978

CXCR4
C-X-C chemokine receptor type 4

4

7

Small-scale

0.698

High

1381227

WBP2
WW domain-binding protein 2

4

9

Small-scale

0.697

High

1394625

TMM51
Transmembrane protein 51

4

5

High-throughput

0.696

High

177705

SMAD7
Mothers against decapentaplegic homolog 7

4

20

Small-scale

0.691

High

181013

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

4

12

High-throughput

0.691

High

1010516

EREP3
Protein ENTREP3

4

15

High-throughput

0.691

High

1358017

TM171
Transmembrane protein 171

4

4

High-throughput

0.691

High

159802

DVL2
Segment polarity protein dishevelled homolog DVL-2

4

20

Small-scale

0.689

High

889324

NUMB
Protein numb homolog

3

2

Small-scale

0.680

High

1121971

ARHG7
Rho guanine nucleotide exchange factor 7

3

3

Small-scale

0.680

High

414411

P53
Cellular tumor antigen p53

4

15

Small-scale

0.680

High

1110928

LAPM5
Lysosomal-associated transmembrane protein 5

3

7

Small-scale

0.674

High

1160965

MAR1
Melanoma antigen recognized by T-cells 1

3

1

Small-scale

0.671

High

1371500

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

3

14

Small-scale

0.670

High

1145765

ERBB4
Receptor tyrosine-protein kinase erbB-4

2

20

Small-scale

0.667

High

1206210

T255A
Transmembrane protein 255A

3

5

High-throughput

0.667

High

1250079

TMM92
Transmembrane protein 92

3

2

High-throughput

0.667

High

861726

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

18

Small-scale

0.665

High

1193160

TIGIT
T-cell immunoreceptor with Ig and ITIM domains

1

0

High-throughput

0.656

High

1394599

NFIP1
NEDD4 family-interacting protein 1

3

17

Small-scale

0.651

High

1278075

MAVS
Mitochondrial antiviral-signaling protein

3

11

Small-scale

0.650

High

144190

UBE2C
Ubiquitin-conjugating enzyme E2 C

1

20

Small-scale

0.647

High

296550

STAM2
Signal transducing adapter molecule 2

1

20

Small-scale

0.647

High

957477

UBC12
NEDD8-conjugating enzyme Ubc12

1

20

Small-scale

0.647

High

1258796

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

20

Small-scale

0.647

High

1281068

UB2Q1
Ubiquitin-conjugating enzyme E2 Q1

1

2

Small-scale

0.647

High

1324409

UB2J2
Ubiquitin-conjugating enzyme E2 J2

1

20

Small-scale

0.647

High

1358419

UB2Q2
Ubiquitin-conjugating enzyme E2 Q2

1

2

Small-scale

0.647

High

1381184

UB2E3
Ubiquitin-conjugating enzyme E2 E3

1

20

Small-scale

0.647

High

1394604

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

20

Small-scale

0.647

High

1394632

UVRAG
UV radiation resistance-associated gene protein

1

2

High-throughput

0.647

High

1394641

UB2D4
Ubiquitin-conjugating enzyme E2 D4

1

20

Small-scale

0.647

High

430242

JUN
Transcription factor Jun

3

6

Small-scale

0.646

High

1159569

NFE2
Transcription factor NF-E2 45 kDa subunit

2

13

Small-scale

0.643

High

466697

GLI1
Zinc finger protein GLI1

2

4

Small-scale

0.641

High

1197056

AMOT
Angiomotin

3

20

Small-scale

0.640

High

1394602

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

2

5

Small-scale

0.639

High

138517

BIN1
Myc box-dependent-interacting protein 1

2

7

Small-scale

0.629

High

853725

MK08
Mitogen-activated protein kinase 8

2

3

Small-scale

0.629

High

1033748

PO5F1
POU domain, class 5, transcription factor 1

2

5

Small-scale

0.629

High

1286633

ILDR1
Immunoglobulin-like domain-containing receptor 1

2

5

High-throughput

0.628

High

1336056

ARRD4
Arrestin domain-containing protein 4

2

20

Small-scale

0.628

High

363713

EGFR
Epidermal growth factor receptor

2

20

High-throughput

0.624

High

667408

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

11

High-throughput

0.624

High

732673

ARRB2
Beta-arrestin-2

2

6

Small-scale

0.624

High

1394594

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

8

Small-scale

0.624

High

132236

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

15

Small-scale

0.618

High

271287

CPNE3
Copine-3

1

2

Small-scale

0.618

High

521411

ARAF
Serine/threonine-protein kinase A-Raf

1

16

Small-scale

0.618

High

857533

NOTC1
Neurogenic locus notch homolog protein 1

1

15

Small-scale

0.618

High

1162691

UBE2S
Ubiquitin-conjugating enzyme E2 S

1

20

Small-scale

0.618

High

1315831

AN13A
Ankyrin repeat domain-containing protein 13A

1

11

Small-scale

0.618

High

1387021

HAVR1
Hepatitis A virus cellular receptor 1

1

2

Small-scale

0.618

High

1394622

RASF1
Ras association domain-containing protein 1

1

8

Small-scale

0.618

High

1294444

DTX1
E3 ubiquitin-protein ligase DTX1

2

1

Small-scale

0.611

High

1394624

NFIP2
NEDD4 family-interacting protein 2

2

17

Small-scale

0.611

High

1391349

WBP1
WW domain-binding protein 1

3

10

High-throughput

0.609

High

771012

RORA
Nuclear receptor ROR-alpha

2

12

Small-scale

0.608

High

1384965

SGK3
Serine/threonine-protein kinase Sgk3

1

20

Small-scale

0.607

High

1394645

SNX9
Sorting nexin-9

1

3

Small-scale

0.604

High

603677

JUNB
Transcription factor JunB

2

8

Small-scale

0.602

High

1014581

SMAD3
Mothers against decapentaplegic homolog 3

2

20

Small-scale

0.602

High

1182853

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

2

6

High-throughput

0.602

High

1394601

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

2

17

High-throughput

0.602

High

1394603

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

2

14

Small-scale

0.602

High

564217

CFTR
Cystic fibrosis transmembrane conductance regulator

2

5

High-throughput

0.601

High

882546

ARRB1
Beta-arrestin-1

2

6

Small-scale

0.601

High

1290935

TAXB1
Tax1-binding protein 1

2

11

Small-scale

0.601

High

1385187

SARAF
Store-operated calcium entry-associated regulatory factor

3

2

High-throughput

0.599

High

1160550

SMN
Survival motor neuron protein

2

0

Small-scale

0.598

High

576504

HNRPL
Heterogeneous nuclear ribonucleoprotein L

2

8

Small-scale

0.595

High

270734

N4BP1
NEDD4-binding protein 1

1

2

Small-scale

0.586

High

1127365

CASL
Enhancer of filamentation 1

1

5

Small-scale

0.586

High

1394638

CBLC
E3 ubiquitin-protein ligase CBL-C

1

7

Small-scale

0.586

High

1394593

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.585

High

165639

SCAM3
Secretory carrier-associated membrane protein 3

2

3

Small-scale

0.584

High

169703

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

17

Small-scale

0.584

High

213996

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

10

Small-scale

0.584

High

219874

SMAD6
Mothers against decapentaplegic homolog 6

2

20

Small-scale

0.584

High

275912

UBP12
Ubiquitin carboxyl-terminal hydrolase 12

2

4

Small-scale

0.584

High

375841

RASK
GTPase KRas

2

7

High-throughput

0.584

High

651405

CBL
E3 ubiquitin-protein ligase CBL

2

12

Small-scale

0.584

High

1028339

MDM2
E3 ubiquitin-protein ligase Mdm2

2

4

Small-scale

0.584

High

1109651

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

13

Small-scale

0.584

High

1159801

OCLN
Occludin

2

5

Small-scale

0.584

High

1371403

DVL3
Segment polarity protein dishevelled homolog DVL-3

2

20

Small-scale

0.584

High

853901

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

18

Small-scale

0.578

High

1332985

MLKL
Mixed lineage kinase domain-like protein

1

2

Small-scale

0.578

High

1394619

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

2

Small-scale

0.578

High

1394639

SUFU
Suppressor of fused homolog

1

1

Small-scale

0.578

High

507318

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

20

Small-scale

0.575

High

228345

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

4

High-throughput

0.561

High

887124

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

Small-scale

0.561

High

943655

SIK1
Serine/threonine-protein kinase SIK1

1

13

Small-scale

0.561

High

1153088

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

1

4

Small-scale

0.561

High

1153872

SMAD2
Mothers against decapentaplegic homolog 2

1

20

Small-scale

0.561

High

1326776

MALD2
MARVEL domain-containing protein 2

1

5

Small-scale

0.561

High

1350941

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

1

Small-scale

0.561

High

1394600

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

2

Small-scale

0.561

High

1394626

CUED1
CUE domain-containing protein 1

2

8

High-throughput

0.549

High

133683

WASL
Actin nucleation-promoting factor WASL

1

9

High-throughput

0.541

High

160932

TMG1
Transmembrane gamma-carboxyglutamic acid protein 1

1

14

High-throughput

0.536

High

270169

LRP3
Low-density lipoprotein receptor-related protein 3

1

14

High-throughput

0.536

High

458463

ADRB2
Beta-2 adrenergic receptor

1

3

Small-scale

0.536

High

773599

COPB2
Coatomer subunit beta'

1

8

High-throughput

0.536

High

867345

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.536

High

966745

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

1114001

CUL3
Cullin-3

1

7

High-throughput

0.536

High

1204465

ARSH
Arylsulfatase H

1

1

High-throughput

0.536

High

1348887

ARRD2
Arrestin domain-containing protein 2

1

20

High-throughput

0.536

High

1371368

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

17

High-throughput

0.536

High

1394621

DISC1
Disrupted in schizophrenia 1 protein

1

2

High-throughput

0.536

High

1394623

TNR19
Tumor necrosis factor receptor superfamily member 19

1

3

High-throughput

0.536

High

1394595

SH3G1
Endophilin-A2

1

11

Small-scale

0.527

High

928319

ATN1
Atrophin-1

1

15

Small-scale

0.527

High

730826

1433S
14-3-3 protein sigma

1

20

High-throughput

0.515

High

1146970

PCBP2
Poly(rC)-binding protein 2

1

14

Small-scale

0.515

High

1394590

SNX18
Sorting nexin-18

1

3

Small-scale

0.515

High

1394612

FXL15
F-box/LRR-repeat protein 15

1

10

Small-scale

0.515

High

1360724

JPH3
Junctophilin-3

1

5

High-throughput

0.515

High

596299

H12
Histone H1.2

1

5

Small-scale

0.512

High

1337266

GLIS3
Zinc finger protein GLIS3

1

4

Small-scale

0.512

High

154742

ARI1A
AT-rich interactive domain-containing protein 1A

1

13

High-throughput

0.501

High

212732

TGFI1
Transforming growth factor beta-1-induced transcript 1 protein

1

9

High-throughput

0.501

High

316424

RMP
Unconventional prefoldin RPB5 interactor 1

1

3

High-throughput

0.501

High

374137

RASN
GTPase NRas

1

8

Small-scale

0.501

High

418720

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

1

2

Small-scale

0.501

High

536353

MTAP2
Microtubule-associated protein 2

1

10

High-throughput

0.501

High

550415

PABP1
Polyadenylate-binding protein 1

1

7

High-throughput

0.501

High

605781

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

20

Small-scale

0.501

High

621714

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

10

High-throughput

0.501

High

621936

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

3

High-throughput

0.501

High

675628

TYY1
Transcriptional repressor protein YY1

1

4

High-throughput

0.501

High

691335

1433T
14-3-3 protein theta

1

20

Small-scale

0.501

High

723052

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

10

High-throughput

0.501

High

728385

AKT1
RAC-alpha serine/threonine-protein kinase

1

20

Small-scale

0.501

High

788540

SCNNA
Epithelial sodium channel subunit alpha

1

20

Small-scale

0.501

High

902325

SCNNB
Epithelial sodium channel subunit beta

1

20

Small-scale

0.501

High

997944

CSK21
Casein kinase II subunit alpha

1

7

Small-scale

0.501

High

1033152

EWS
RNA-binding protein EWS

1

4

High-throughput

0.501

High

1038339

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

19

Small-scale

0.501

High

1122136

UBP2L
Ubiquitin-associated protein 2-like

1

11

High-throughput

0.501

High

1134329

IMB1
Importin subunit beta-1

1

10

Small-scale

0.501

High

1150795

SF01
Splicing factor 1

1

3

High-throughput

0.501

High

1213529

UBAP2
Ubiquitin-associated protein 2

1

11

High-throughput

0.501

High

1245407

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

2

High-throughput

0.501

High

1309235

KSR1
Kinase suppressor of Ras 1

1

19

Small-scale

0.501

High

1313032

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

1

3

High-throughput

0.501

High

1326565

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

4

High-throughput

0.501

High

1329079

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

11

High-throughput

0.501

High

1329211

MYCT1
Myc target protein 1

1

1

High-throughput

0.501

High

1347527

SMRC2
SWI/SNF complex subunit SMARCC2

1

12

High-throughput

0.501

High

1370687

SMRC1
SWI/SNF complex subunit SMARCC1

1

8

High-throughput

0.501

High

1379990

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

1

9

High-throughput

0.501

High

1389454

DAZP1
DAZ-associated protein 1

1

19

High-throughput

0.501

High

1394587

RBM14
RNA-binding protein 14

1

12

High-throughput

0.501

High

1394589

TREF1
Transcriptional-regulating factor 1

1

7

High-throughput

0.501

High

1394592

MINT
Msx2-interacting protein

1

9

High-throughput

0.501

High

1394605

TTYH3
Protein tweety homolog 3

1

2

High-throughput

0.501

High

1394615

RPAP3
RNA polymerase II-associated protein 3

1

15

High-throughput

0.501

High

1394637

STRP2
Striatin-interacting protein 2

1

1

High-throughput

0.501

High

1394640

M3K2
Mitogen-activated protein kinase kinase kinase 2

1

11

High-throughput

0.501

High

1126744

BECN1
Beclin-1

1

1

Small-scale

0.481

High

48378

UBA6
Ubiquitin-like modifier-activating enzyme 6

1

5

High-throughput

0.479

High

67143

UBP27
Ubiquitin carboxyl-terminal hydrolase 27

1

4

Small-scale

0.479

High

126744

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

133783

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

5

High-throughput

0.479

High

159392

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

20

Small-scale

0.479

High

163345

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

7

Small-scale

0.479

High

167954

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

14

Small-scale

0.479

High

176083

KDM6B
Lysine-specific demethylase 6B

1

4

Small-scale

0.479

High

190248

MOT4
Monocarboxylate transporter 4

1

3

Small-scale

0.479

High

213524

MTSS1
Protein MTSS 1

1

14

Small-scale

0.479

High

227642

SPOP
Speckle-type POZ protein

1

3

Small-scale

0.479

High

244491

MGRN1
E3 ubiquitin-protein ligase MGRN1

1

1

Small-scale

0.479

High

250772

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

8

Small-scale

0.479

High

287600

LRP6
Low-density lipoprotein receptor-related protein 6

1

1

Small-scale

0.479

High

362062

AATM
Aspartate aminotransferase, mitochondrial

1

1

Small-scale

0.479

High

372854

MYC
Myc proto-oncogene protein

1

6

High-throughput

0.479

High

402401

GBA1
Lysosomal acid glucosylceramidase

1

1

Small-scale

0.479

High

424040

ITB3
Integrin beta-3

1

8

Small-scale

0.479

High

424996

ADT2
ADP/ATP translocase 2

1

9

Small-scale

0.479

High

443476

CDK1
Cyclin-dependent kinase 1

1

6

Small-scale

0.479

High

456826

ANXA2
Annexin A2

1

11

Small-scale

0.479

High

466410

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

467579

4F2
Amino acid transporter heavy chain SLC3A2

1

4

High-throughput

0.479

High

469321

ASNS
Asparagine synthetase [glutamine-hydrolyzing]

1

3

Small-scale

0.479

High

472342

CFAH
Complement factor H

1

3

Small-scale

0.479

High

535414

BIP
Endoplasmic reticulum chaperone BiP

1

15

High-throughput

0.479

High

537713

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.479

High

551202

PCNA
Proliferating cell nuclear antigen

1

3

High-throughput

0.479

High

560481

IFM1
Interferon-induced transmembrane protein 1

1

3

High-throughput

0.479

High

566006

EF2
Elongation factor 2

1

10

Small-scale

0.479

High

566302

K1C13
Keratin, type I cytoskeletal 13

1

1

Small-scale

0.479

High

581231

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

589421

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

601404

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

608701

DDX5
Probable ATP-dependent RNA helicase DDX5

1

7

Small-scale

0.479

High

622665

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

7

Small-scale

0.479

High

639292

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

6

Small-scale

0.479

High

641651

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

Small-scale

0.479

High

647625

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

5

High-throughput

0.479

High

687710

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

6

Small-scale

0.479

High

696222

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

4

High-throughput

0.479

High

699010

CALX
Calnexin

1

5

Small-scale

0.479

High

710427

EPHA2
Ephrin type-A receptor 2

1

9

High-throughput

0.479

High

712258

TKT
Transketolase

1

5

Small-scale

0.479

High

761820

HSP74
Heat shock 70 kDa protein 4

1

13

Small-scale

0.479

High

766770

PHB1
Prohibitin 1

1

7

High-throughput

0.479

High

768900

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

787441

TGFR1
TGF-beta receptor type-1

1

19

Small-scale

0.479

High

810289

RL3
Large ribosomal subunit protein uL3

1

6

Small-scale

0.479

High

821506

TCPZ
T-complex protein 1 subunit zeta

1

13

Small-scale

0.479

High

843871

HD
Huntingtin

1

4

Small-scale

0.479

High

853509

UBP5
Ubiquitin carboxyl-terminal hydrolase 5

1

20

High-throughput

0.479

High

870655

MAOX
NADP-dependent malic enzyme

1

1

Small-scale

0.479

High

872634

SOX2
Transcription factor SOX-2

1

7

High-throughput

0.479

High

882091

TCPG
T-complex protein 1 subunit gamma

1

12

Small-scale

0.479

High

901486

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

902004

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.479

High

906442

DHB4
Peroxisomal multifunctional enzyme type 2

1

4

Small-scale

0.479

High

908444

HDGF
Hepatoma-derived growth factor

1

3

Small-scale

0.479

High

910164

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

911053

IMA1
Importin subunit alpha-1

1

7

High-throughput

0.479

High

925965

TCP4
Activated RNA polymerase II transcriptional coactivator p15

1

2

Small-scale

0.479

High

927103

ATX3
Ataxin-3

1

4

Small-scale

0.479

High

939643

BID
BH3-interacting domain death agonist

1

1

Small-scale

0.479

High

953617

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

955476

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

962383

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

978225

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

988610

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1008021

JAG1
Protein jagged-1

1

9

Small-scale

0.479

High

1015682

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1031499

IFM3
Interferon-induced transmembrane protein 3

1

3

High-throughput

0.479

High

1041228

CAV1
Caveolin-1

1

2

Small-scale

0.479

High

1060121

BAX
Apoptosis regulator BAX

1

3

Small-scale

0.479

High

1064468

DSC1
Desmocollin-1

1

2

Small-scale

0.479

High

1097722

STK3
Serine/threonine-protein kinase 3

1

19

Small-scale

0.479

High

1100965

G3BP1
Ras GTPase-activating protein-binding protein 1

1

3

Small-scale

0.479

High

1106660

SMAD4
Mothers against decapentaplegic homolog 4

1

20

High-throughput

0.479

High

1116276

PTC1
Protein patched homolog 1

1

14

Small-scale

0.479

High

1120288

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

19

Small-scale

0.479

High

1134029

ZN638
Zinc finger protein 638

1

10

High-throughput

0.479

High

1138514

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

10

Small-scale

0.479

High

1151820

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1153304

AAAT
Neutral amino acid transporter B(0)

1

6

High-throughput

0.479

High

1153783

NCOA1
Nuclear receptor coactivator 1

1

3

Small-scale

0.479

High

1209521

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

10

High-throughput

0.479

High

1211668

MARH8
E3 ubiquitin-protein ligase MARCHF8

1

3

High-throughput

0.479

High

1218633

OTU1
Ubiquitin thioesterase OTU1

1

1

Small-scale

0.479

High

1233845

GRAM4
GRAM domain-containing protein 4

1

1

Small-scale

0.479

High

1249118

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

1255080

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1259628

H2AV
Histone H2A.V

1

8

Small-scale

0.479

High

1270947

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1276642

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

1288118

MARH3
E3 ubiquitin-protein ligase MARCHF3

1

3

High-throughput

0.479

High

1295053

LRAD3
Low-density lipoprotein receptor class A domain-containing protein 3

1

7

Small-scale

0.479

High

1323682

K2C78
Keratin, type II cytoskeletal 78

1

1

Small-scale

0.479

High

1334511

RN149
E3 ubiquitin-protein ligase RNF149

1

7

High-throughput

0.479

High

1339659

TNIP2
TNFAIP3-interacting protein 2

1

3

High-throughput

0.479

High

1347140

WDR48
WD repeat-containing protein 48

1

6

Small-scale

0.479

High

1352299

RN128
E3 ubiquitin-protein ligase RNF128

1

6

High-throughput

0.479

High

1356977

PDC6I
Programmed cell death 6-interacting protein

1

10

High-throughput

0.479

High

1366862

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1370989

TNPO1
Transportin-1

1

10

Small-scale

0.479

High

1386536

OPTN
Optineurin

1

17

High-throughput

0.479

High

1394591

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

1

High-throughput

0.479

High

1394598

PD1L2
Programmed cell death 1 ligand 2

1

6

Small-scale

0.479

High

1394611

DNJC5
DnaJ homolog subfamily C member 5

1

4

High-throughput

0.479

High

1394613

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1394614

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

1394616

TRPV4
Transient receptor potential cation channel subfamily V member 4

1

2

Small-scale

0.479

High

1394617

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1394620

ANLN
Anillin

1

1

High-throughput

0.479

High

1394628

ELOV5
Very long chain fatty acid elongase 5

1

1

High-throughput

0.479

High

1394629

GGA3
ADP-ribosylation factor-binding protein GGA3

1

16

Small-scale

0.479

High

1394633

HDAC6
Protein deacetylase HDAC6

1

4

High-throughput

0.479

High

1394634

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1394635

DDX20
Probable ATP-dependent RNA helicase DDX20

1

18

Small-scale

0.479

High

1394642

SHLB1
Endophilin-B1

1

9

Small-scale

0.479

High

1394644

TRAF6
TNF receptor-associated factor 6

1

20

Small-scale

0.479

High

1394646

NEMO
NF-kappa-B essential modulator

1

9

Small-scale

0.479

High

442444

GELS
Gelsolin

1

0

Small-scale

0.458

High

644539

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

1

0

Small-scale

0.458

High

810630

COIA1
Collagen alpha-1(XVIII) chain [Cleaved into: Endostatin; Non-collagenous domain 1

1

0

High-throughput

0.458

High

1233415

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

1381934

CK052
Uncharacterized protein C11orf52

1

0

High-throughput

0.458

High

1386455

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.458

High

1394588

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

Small-scale

0.458

High

1394627

GEMI8
Gem-associated protein 8

1

0

Small-scale

0.458

High

190459

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.445

High

284602

ECI2
Enoyl-CoA delta isomerase 2

1

5

High-throughput

0.445

High

388443

B3AT
Band 3 anion transport protein

1

3

High-throughput

0.445

High

638498

FPR1
fMet-Leu-Phe receptor

1

7

High-throughput

0.445

High

669353

ACKR3
Atypical chemokine receptor 3

1

6

High-throughput

0.445

High

788992

TGFR2
TGF-beta receptor type-2

1

19

High-throughput

0.445

High

943534

G6PT2
Glucose-6-phosphate exchanger SLC37A1

1

8

High-throughput

0.445

High

944415

SYJ2B
Synaptojanin-2-binding protein

1

13

High-throughput

0.445

High

1010090

DLK1
Protein delta homolog 1

1

17

High-throughput

0.445

High

1063008

DDR1
Epithelial discoidin domain-containing receptor 1

1

14

Small-scale

0.445

High

1092626

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

6

High-throughput

0.445

High

1147821

DHC24
Delta(24)-sterol reductase

1

2

High-throughput

0.445

High

1226220

CP135
Centrosomal protein of 135 kDa

1

10

High-throughput

0.445

High

1242200

NPAL3
NIPA-like protein 3

1

3

High-throughput

0.445

High

1273787

NIPA1
Magnesium transporter NIPA1

1

3

High-throughput

0.445

High

1313798

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.445

High

1340554

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.445

High

1352566

G6PT3
Glucose-6-phosphate exchanger SLC37A2

1

8

High-throughput

0.445

High

1394606

S22A4
Solute carrier family 22 member 4

1

8

High-throughput

0.445

High

1394618

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.445

High

174582

TRI66
Tripartite motif-containing protein 66

1

10

High-throughput

0.437

High

1095098

KLF10
Krueppel-like factor 10

1

6

Small-scale

0.437

High

1241927

FBX42
F-box only protein 42

1

5

Small-scale

0.437

High

1278251

DHX29
ATP-dependent RNA helicase DHX29

1

10

Small-scale

0.437

High

337129

NPT2B
Sodium-dependent phosphate transport protein 2B

1

0

High-throughput

0.426

High

1384954

CC127
Coiled-coil domain-containing protein 127

1

0

High-throughput

0.426

High

947035

DSCR9
Down syndrome critical region protein 9

1

1

High-throughput

0.417

High

604153

CXA1
Gap junction alpha-1 protein

1

2

High-throughput

0.408

High

1339262

REPS2
RalBP1-associated Eps domain-containing protein 2

1

5

High-throughput

0.408

High

1352344

RHBL4
Rhomboid-related protein 4

1

2

High-throughput

0.408

High

548092

PSPC
Surfactant protein C

1

4

High-throughput

0.407

High

1381013

S35B4
Nucleotide sugar transporter SLC35B4

1

2

High-throughput

0.407

High

1387391

ESS2
Splicing factor ESS-2 homolog

1

1

High-throughput

0.373

High

1394636

K1210
Acrosomal protein KIAA1210

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025