HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: PYGO2 (Q9BRQ0)
Pygopus homolog 2
Gene: PYGO2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	31073027, 24981860, 17113272, 21399610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0060070 - canonical Wnt signaling pathway GO:1990907 - beta-catenin-TCF complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 1426 Hs			1 406
+	Hs
		131752 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		PYGO1_HUMAN (35-406): 2.01e-140: 408: 36.90
+	Hs
		1200134 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		PYGO1_HUMAN (35-406): 2.01e-140: 408: 36.90
+	Hs
		1200128 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		PYGO2_HUMAN (1-406): 3.28e-137: 399: 100.00