HitPredict

Interactor 1: BCL9 (O00512)
B-cell CLL/lymphoma 9 protein (B-cell lymphoma 9 protein) (Bcl-9) (Protein legless homolog)
Gene: BCL9

Interactor 2: LHX6 (Q9UPM6)
LIM/homeobox protein Lhx6 (LIM homeobox protein 6) (LIM/homeobox protein Lhx6.1)
Gene: LHX6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1426 Hs			1 363
+	Hs
		131726 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX8_HUMAN (8-348): 4.5e-61: 201: 51.30
+	Hs
		131710 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		ISL1_HUMAN (60-360): 3.14e-56: 189: 26.94
+	Hs
		131737 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		ISL2_HUMAN (61-343): 2.94e-53: 181: 28.05
+	Hs
		131702 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65
+	Hs
		131704 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46
+	Hs
		131711 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LMO4_HUMAN (43-181): 2.86e-24: 99.4: 39.44
+	Hs
		131736 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81
+	Hs
		131749 BCL9_HUMAN (1-1426): 4.24e-149: 492: 100.00		LHX3_HUMAN (4-124): 2.09e-18: 87.7: 14.52
+	Hs
		1200133 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX6_HUMAN (1-363): 6.25e-83: 258: 100.00
+	Hs
		899924 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		ISL1_HUMAN (60-360): 3.14e-56: 189: 26.94
+	Hs
		822688 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65
+	Hs
		1200126 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		ISL2_HUMAN (61-343): 2.94e-53: 181: 28.05
+	Hs
		839836 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46
+	Hs
		839774 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46
+	Hs
		822650 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX1_HUMAN (70-362): 1.71e-52: 180: 26.65
+	Hs
		839785 KMT2C_HUMAN (40-881): 1.95e-11: 71.6: 8.19		LHX2_HUMAN (27-199): 1.4e-47: 167: 34.46
+	Hs
		903746 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LMO4_HUMAN (43-181): 2.86e-24: 99.4: 39.44
+	Hs
		1281194 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81
+	Hs
		1350240 CHD7_HUMAN (439-953): 5.16e-20: 99.7: 12.01		LHX3_HUMAN (4-124): 2.09e-18: 87.7: 14.52
+	Hs
		1200125 BCL9L_HUMAN (4-1218): 2.15e-17: 91: 11.06		LHX4_HUMAN (3-124): 3.11e-19: 90: 11.81