Protein: S10AE
Protein S100-A14 (S100 calcium-binding protein A14) (S114)

Gene: S10AE, S100A14
Organism: Homo sapiens
Interactions: 85
UniProt ID: Q9HCY8

Gene Ontology (top 5):
GO:0005509 - calcium ion binding
GO:0005615 - extracellular space
GO:0006915 - apoptotic process
GO:0032496 - response to lipopolysaccharide
GO:0034142 - toll-like receptor 4 signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1390843

S10AG
Protein S100-A16

4

18

High-throughput

0.911

High

1405481

S10AD
Protein S100-A13

2

18

High-throughput

0.783

High

641265

FGFR2
Fibroblast growth factor receptor 2

1

4

High-throughput

0.698

High

456858

ANXA2
Annexin A2

1

13

High-throughput

0.618

High

1439505

PD1L1
Programmed cell death 1 ligand 1

1

7

High-throughput

0.618

High

1439507

HECW2
E3 ubiquitin-protein ligase HECW2

1

5

High-throughput

0.553

High

170363

AURKA
Aurora kinase A

1

9

High-throughput

0.541

High

1132440

CASP8
Caspase-8

1

5

High-throughput

0.541

High

1154449

STK11
Serine/threonine-protein kinase STK11

1

3

High-throughput

0.541

High

861790

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

5

High-throughput

0.536

High

1023893

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

9

High-throughput

0.536

High

848444

MAGA6
Melanoma-associated antigen 6

1

5

High-throughput

0.523

High

602839

AATC
Aspartate aminotransferase, cytoplasmic

1

6

High-throughput

0.515

High

736473

NAC1
Sodium/calcium exchanger 1

1

18

Small-scale

0.501

High

773032

MYH9
Myosin-9

1

15

Small-scale

0.501

High

1350775

TRPM4
Transient receptor potential cation channel subfamily M member 4

1

12

Small-scale

0.501

High

728435

AKT1
RAC-alpha serine/threonine-protein kinase

1

12

High-throughput

0.494

High

1106715

SMAD4
Mothers against decapentaplegic homolog 4

1

4

High-throughput

0.494

High

66522

RASFA
Ras association domain-containing protein 10

1

2

High-throughput

0.489

High

876398

PTSS1
Phosphatidylserine synthase 1

1

8

High-throughput

0.489

High

943499

DSCR6
Protein ripply3

1

8

High-throughput

0.489

High

1013342

HTRA4
Serine protease HTRA4

1

9

High-throughput

0.489

High

1055636

GABPA
GA-binding protein alpha chain

1

8

High-throughput

0.489

High

1156059

ZIC1
Zinc finger protein ZIC 1

1

7

High-throughput

0.489

High

1381471

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

5

High-throughput

0.489

High

1417193

SRRT
Serrate RNA effector molecule homolog

1

2

High-throughput

0.489

High

1437874

PRD16
Histone-lysine N-methyltransferase PRDM16

1

6

High-throughput

0.489

High

1439504

ST7
Suppressor of tumorigenicity 7 protein

1

5

High-throughput

0.489

High

1439512

TDRKH
Tudor and KH domain-containing protein

1

2

High-throughput

0.489

High

537948

HSP7C
Heat shock cognate 71 kDa protein

1

6

High-throughput

0.479

High

577898

PLAK
Junction plakoglobin

1

7

High-throughput

0.479

High

587815

DESP
Desmoplakin

1

4

High-throughput

0.479

High

762255

TRY3
Trypsin-3

1

4

High-throughput

0.479

High

762366

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

5

High-throughput

0.479

High

831466

CCNF
Cyclin-F

1

4

High-throughput

0.479

High

888336

MCM2
DNA replication licensing factor MCM2

1

8

High-throughput

0.479

High

926686

HIRA
Protein HIRA

1

1

High-throughput

0.479

High

1030497

FABP5
Fatty acid-binding protein 5

1

3

High-throughput

0.479

High

1036802

DSG1
Desmoglein-1

1

7

High-throughput

0.479

High

1041701

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

1

Small-scale

0.479

High

1064481

DSC1
Desmocollin-1

1

4

High-throughput

0.479

High

1085621

FOXO1
Forkhead box protein O1

1

7

High-throughput

0.479

High

1118255

BLMH
Bleomycin hydrolase

1

2

High-throughput

0.479

High

1213841

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.479

High

1256484

UBN2
Ubinuclein-2

1

4

High-throughput

0.479

High

1288379

TLK2
Serine/threonine-protein kinase tousled-like 2

1

10

High-throughput

0.479

High

1399459

SPB12
Serpin B12

1

9

High-throughput

0.479

High

1439503

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

5

High-throughput

0.479

High

1439506

CALL5
Calmodulin-like protein 5

1

1

High-throughput

0.479

High

251346

CIDEA
Lipid transferase CIDEA

1

0

High-throughput

0.458

High

762093

MPI
Mannose-6-phosphate isomerase

1

0

High-throughput

0.458

High

1439513

UCHL5
Ubiquitin carboxyl-terminal hydrolase isozyme L5

1

7

Small-scale

0.457

High

411066

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

18

High-throughput

0.445

High

554256

BMP4
Bone morphogenetic protein 4

1

3

High-throughput

0.445

High

106683

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

292305

B3GL1
UDP-GalNAc:beta-1,3-N-acetylgalactosaminyltransferase 1

1

5

High-throughput

0.437

High

294361

CD123
Translation initiation factor eIF2 assembly protein

1

9

High-throughput

0.437

High

343281

ERR2
Steroid hormone receptor ERR2

1

16

High-throughput

0.437

High

347941

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.437

High

623552

RO52
E3 ubiquitin-protein ligase TRIM21

1

10

High-throughput

0.437

High

703071

DPOD1
DNA polymerase delta catalytic subunit

1

1

High-throughput

0.437

High

971114

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

7

High-throughput

0.437

High

1118166

DX39B
Spliceosome RNA helicase DDX39B

1

9

High-throughput

0.437

High

1213880

KPLCE
Protein KPLCE

1

1

High-throughput

0.437

High

1367337

ESR2
Estrogen receptor beta

1

17

High-throughput

0.437

High

1394268

GMCL1
Germ cell-less protein-like 1

1

4

High-throughput

0.437

High

1428544

DDX24
ATP-dependent RNA helicase DDX24

1

10

High-throughput

0.437

High

1439502

UBN1
Ubinuclein-1

1

2

High-throughput

0.437

High

406985

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.426

High

1092656

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

1249443

OLFM4
Olfactomedin-4

1

0

High-throughput

0.426

High

261282

NSMA
Sphingomyelin phosphodiesterase 2

1

3

High-throughput

0.407

High

1227502

A16L1
Autophagy-related protein 16-1

1

3

High-throughput

0.407

High

1404062

MYCBP
c-Myc-binding protein

1

1

High-throughput

0.407

High

1408338

PKP2
Plakophilin-2

1

8

High-throughput

0.407

High

1414726

RSRP1
Arginine/serine-rich protein 1

1

2

High-throughput

0.407

High

1439508

TCAL9
Transcription elongation factor A protein-like 9

1

2

High-throughput

0.407

High

1439510

LRCH1
Leucine-rich repeat and calponin homology domain-containing protein 1

1

3

High-throughput

0.407

High

559508

XRCC5
X-ray repair cross-complementing protein 5

1

0

High-throughput

0.279

Low

1439509

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.279

Low

1311321

CDAN1
Codanin-1

1

0

High-throughput

0.249

Low

1439511

CDIN1
CDAN1-interacting nuclease 1

1

0

High-throughput

0.249

Low

1439514

CABIN
Calcineurin-binding protein cabin-1

1

0

High-throughput

0.249

Low

839628

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.232

Low

1231667

RL7L
Ribosomal protein uL30-like

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025