HitPredict

Interactor 1: TRIM8 (Q9BZR9)
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Gene: TRIM8

Interactor 2: TRIM8 (Q9BZR9)
E3 ubiquitin-protein ligase TRIM8 (EC 2.3.2.27) (Glioblastoma-expressed RING finger protein) (RING finger protein 27) (RING-type E3 ubiquitin transferase TRIM8) (Tripartite motif-containing protein 8)
Gene: TRIM8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.858

The method score is based on:

Property Details
Experiments 11331580, 22493164, 22829933
Identification Methods two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains zf-RING_UBOX~zf-RING_UBOX
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0007249 - canonical NF-kappaB signal transduction
and 16 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 551
Hs

1 551
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Last updated: 15 Jul 2024