HitPredict

Interactor 1: UBE2O (Q9C0C9)
(E3-independent) E2 ubiquitin-conjugating enzyme (EC 2.3.2.24) (E2/E3 hybrid ubiquitin-protein ligase UBE2O) (Ubiquitin carrier protein O) (Ubiquitin-conjugating enzyme E2 O) (Ubiquitin-conjugating enzyme E2 of 230 kDa) (Ubiquitin-conjugating enzyme E2-230K) (Ubiquitin-protein ligase O)
Gene: UBE2O

Interactor 2: E41L5 (Q9HCM4)
Band 4.1-like protein 5 (Erythrocyte membrane protein band 4.1-like 5)
Gene: EPB41L5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	28514442, 33961781, 34921745
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1292 Hs			1 733
+	Hs
		663991 UBE2O_HUMAN (40-1292): 0: 1481: 100.00		PTN4_HUMAN (1-629): 1.46e-155: 476: 26.10
+	Hs
		640273 UBE2O_HUMAN (40-1292): 0: 1481: 100.00		PTN3_HUMAN (1-573): 9.16e-129: 406: 22.88
+	Hs
		204730 UBE2O_HUMAN (40-1292): 0: 1481: 100.00		E41L2_HUMAN (16-581): 4.94e-127: 404: 31.49
+	Hs
		719415 UBE2A_HUMAN (956-1112): 5.42e-42: 152: 26.75		MERL_HUMAN (36-638): 3.11e-118: 369: 20.23
+	Hs
		919803 UB2D2_HUMAN (953-1106): 1.71e-62: 211: 22.29		MYLIP_HUMAN (45-324): 3.52e-31: 129: 29.12
+	Hs
		1264347 UB2D4_HUMAN (953-1106): 2.59e-62: 210: 21.02		MYLIP_HUMAN (45-324): 3.52e-31: 129: 29.12
+	Hs
		849386 UB2D1_HUMAN (953-1106): 1.82e-61: 208: 19.11		MYLIP_HUMAN (45-324): 3.52e-31: 129: 29.12
+	Hs
		895861 UB2D3_HUMAN (953-1106): 2.98e-61: 207: 22.93		MYLIP_HUMAN (45-324): 3.52e-31: 129: 29.12
+	Hs
		896505 UBE2N_HUMAN (956-1103): 1.44e-45: 163: 22.52		MYLIP_HUMAN (45-324): 3.52e-31: 129: 29.12