HitPredict

Interactor 1: ATG3 (Q9CPX6)
Ubiquitin-like-conjugating enzyme ATG3 (EC 2.3.2.-) (Autophagy-related protein 3) (APG3-like)
Gene: ATG3

Interactor 2: ATG12 (Q9CQY1)
Ubiquitin-like protein ATG12 (Autophagy-related protein 12) (APG12-like)
Gene: ATG12

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	24191030, 25686249, 20723759
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0006914 - autophagy GO:0016236 - macroautophagy GO:0034274 - Atg12-Atg5-Atg16 complex and 1 others more... GO:0061723 - glycophagy
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 314 Mm			1 141
+	Hs
		296769 ATG3_HUMAN (1-314): 2.78e-155: 438: 97.45		ATG12_HUMAN (1-141): 4.68e-74: 218: 88.65
+	Rn
		1103290 ATG3_RAT (1-314): 1.21e-155: 439: 98.41		ATG12_RAT (1-141): 2.01e-72: 214: 89.36
+	At
		1013370 ATG3_ARATH (4-314): 1.86e-123: 357: 44.65		AT12B_ARATH (44-141): 5.51e-46: 146: 42.86
+	Sc
		748356 ATG3_YEAST (8-311): 4.64e-96: 288: 32.84		ATG12_YEAST (37-141): 1.74e-36: 125: 28.57
+	Mm
		1246815 ATG10_MOUSE (173-301): 8.32e-44: 151: 20.59		ATG12_MOUSE (1-141): 1.06e-76: 225: 100.00
+	Hs
		296760 ATG10_HUMAN (173-301): 5.49e-41: 143: 20.59		ATG12_HUMAN (1-141): 4.68e-74: 218: 88.65