HitPredict

Interactor 1: LTOR1 (Q9CQ22)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18)
Gene: Lamtor1

Interactor 2: TSC1 (Q9EP53)
Hamartin (Tuberous sclerosis 1 protein homolog)
Gene: TSC1

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28671696
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005765 - lysosomal membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 161 Mm			1 1161
+	Hs
		1152011 LTOR1_HUMAN (1-161): 7.79e-89: 257: 99.38		TSC1_HUMAN (1-1161): 0: 767: 86.98
+	Hs
		254489 LTOR1_HUMAN (1-161): 7.79e-89: 257: 99.38		ROCK2_HUMAN (398-1090): 3.16e-25: 116: 12.76
+	Hs
		1137873 LTOR1_HUMAN (1-161): 7.79e-89: 257: 99.38		MRCKA_HUMAN (487-978): 2.97e-23: 109: 12.91
+	Hs
		1067435 LTOR1_HUMAN (1-161): 7.79e-89: 257: 99.38		EEA1_HUMAN (408-851): 3.09e-13: 76.8: 8.35
+	Hs
		1152042 LTOR1_HUMAN (1-161): 7.79e-89: 257: 99.38		KI16B_HUMAN (692-962): 9.32e-09: 62.1: 14.77