HitPredict

Interactor 1: RING2 (Q9CQJ4)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2)
Gene: Rnf2

Interactor 2: HM20B (Q9Z104)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related (SMARCE1-related protein) (BRCA2-associated factor 35) (HMG box-containing protein 20B) (Structural DNA-binding protein BRAF35)
Gene: Hmg20b

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22496869
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006325 - chromatin organization GO:0016604 - nuclear body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 336 Mm			1 317
+	Mm
		1321738 RING2_MOUSE (1-336): 2.13e-106: 316: 100.00		HM20A_MOUSE (29-313): 2.15e-62: 203: 50.52
+	Hs
		1281233 RING2_HUMAN (1-336): 2.74e-106: 315: 99.70		SMCE1_HUMAN (74-315): 3.75e-37: 138: 20.78
+	Hs
		1300908 RING2_HUMAN (1-336): 2.74e-106: 315: 99.70		CIC_HUMAN (10-201): 4.21e-30: 122: 14.51
+	Hs
		996853 RING2_HUMAN (1-336): 2.74e-106: 315: 99.70		SSRP1_HUMAN (50-233): 1.04e-29: 120: 19.79
+	Mm
		1207287 RING2_MOUSE (1-336): 2.13e-106: 316: 100.00		TOX4_MOUSE (2-186): 1.16e-28: 117: 20.73
+	Mm
		818761 RING2_MOUSE (1-336): 2.13e-106: 316: 100.00		SOX2_MOUSE (33-153): 5.92e-30: 117: 21.49
+	Hs
		818385 RING2_HUMAN (1-336): 2.74e-106: 315: 99.70		SOX2_HUMAN (63-153): 9.86e-30: 117: 27.47
+	Hs
		1313366 TRAF4_HUMAN (42-321): 1.6e-33: 130: 10.49		HM20A_HUMAN (9-313): 1.64e-64: 208: 47.60
+	Hs
		988011 RING1_HUMAN (10-336): 3.44e-66: 215: 51.75		CIC_HUMAN (10-201): 4.21e-30: 122: 14.51
+	Hs
		537081 TRI27_HUMAN (36-244): 3.8e-32: 127: 14.22		HM20A_HUMAN (9-313): 1.64e-64: 208: 47.60
+	Hs
		1300927 PCGF6_HUMAN (30-293): 1.72e-44: 157: 15.36		CIC_HUMAN (10-201): 4.21e-30: 122: 14.51
+	Hs
		717548 BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83		SOX2_HUMAN (63-153): 9.86e-30: 117: 27.47
+	Hs
		717704 BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83		TFAM_HUMAN (70-257): 8.4e-30: 115: 16.67
+	Hs
		585039 RO52_HUMAN (36-249): 1.63e-36: 139: 13.08		CIC_HUMAN (10-201): 4.21e-30: 122: 14.51
+	Hs
		1311540 PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56		SOX17_HUMAN (5-175): 1.13e-33: 129: 16.96
+	Mm
		620784 PCGF2_MOUSE (34-332): 1.26e-37: 139: 16.17		SOX2_MOUSE (33-153): 5.92e-30: 117: 21.49
+	Hs
		817987 TRI26_HUMAN (36-283): 2.67e-35: 136: 17.05		SOX2_HUMAN (63-153): 9.86e-30: 117: 27.47
+	Hs
		1223389 TRI22_HUMAN (44-307): 2.59e-32: 127: 14.44		CIC_HUMAN (10-201): 4.21e-30: 122: 14.51
+	Hs
		818411 PCGF1_HUMAN (28-336): 1.37e-35: 131: 16.56		SOX2_HUMAN (63-153): 9.86e-30: 117: 27.47
+	Hs
		70542 BMI1_HUMAN (34-332): 2.52e-42: 151: 16.83		HGB1A_HUMAN (32-139): 9.53e-17: 79.5: 30.00