Interactor 1: NEMO (Q9GYV5)
NF-kappa-B essential modulator (Inhibitor of nuclear factor kappa B kinase subunit gamma) (DmIKKgamma) (NEMO homolog)
Gene: key

Interactor 2: IKKB (Q9VEZ5)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappaB kinase subunit beta) (EC 2.7.11.10) (Cactus kinase IKK) (IKK-like protein) (Immune response deficient protein 5) (Lipopolysaccharide-activated kinase) (DLAK)
Gene: IKKbeta

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.55 0.665

The method score is based on:

Property Details
Experiments 11018014, 29097655, 23749869, 22036573
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002230 - positive regulation of defense response to virus by host
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006963 - positive regulation of antibacterial peptide biosynthetic process
GO:0030163 - protein catabolic process
and 4 others

more...

Homologous interactions 0

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Last updated: 15 Jul 2024