HitPredict

Interactor 1: COMD5 (Q9GZQ3)
COMM domain-containing protein 5 (Hypertension-related calcium-regulated gene protein) (HCaRG)
Gene: COMMD5

Interactor 2: COMDA (Q9Y6G5)
COMM domain-containing protein 10
Gene: COMMD10

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.88	1.00	0.942

Property	Details
Experiments	28514442, 32296183, 33961781, unassigned1304, 37172566, 23563313
Identification Methods	affinity chromatography technology, two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	COMM_domain~COMM_domain
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 224 Hs			1 202
+	Hs
		1326122 COMD5_HUMAN (1-224): 5.57e-143: 399: 100.00		COMD3_HUMAN (9-202): 2.18e-61: 191: 21.32
+	Hs
		1202647 COMD5_HUMAN (1-224): 5.57e-143: 399: 100.00		COMD7_HUMAN (10-200): 3.3e-59: 186: 14.14
+	Hs
		1326117 COMD5_HUMAN (1-224): 5.57e-143: 399: 100.00		COMD4_HUMAN (9-201): 6.36e-43: 144: 20.73
+	Hs
		1204176 COMD5_HUMAN (1-224): 5.57e-143: 399: 100.00		COMD2_HUMAN (7-198): 2.37e-09: 56.4: 11.98