HitPredict

Interactor 1: MCLN1 (Q9GZU1)
Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1)
Gene: MCOLN1

Interactor 2: MCLN1 (Q9GZU1)
Mucolipin-1 (ML1) (MG-2) (Mucolipidin) (Transient receptor potential channel mucolipin 1) (TRPML1)
Gene: MCOLN1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 29019983, 30305615
Identification Methods 3D electron microscopy, molecular sieving
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PKD_channel~PKD_channel
Common GO terms GO:0001891 - phagocytic cup
GO:0002250 - adaptive immune response
GO:0005261 - monoatomic cation channel activity
GO:0005262 - calcium channel activity
GO:0005381 - iron ion transmembrane transporter activity
and 29 others

more...
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 580
Hs

1 580
+ Mm
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024