HitPredict

Interactor 1: UBA5 (Q9GZZ9)
Ubiquitin-like modifier-activating enzyme 5 (Ubiquitin-activating enzyme 5) (ThiFP1) (UFM1-activating enzyme) (Ubiquitin-activating enzyme E1 domain-containing protein 1)
Gene: UBA5

Interactor 2: UFC1 (Q9Y3C8)
Ubiquitin-fold modifier-conjugating enzyme 1 (Ufm1-conjugating enzyme 1)
Gene: UFC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	35271311, 28514442, 24966333, 33961781, 20562859
Identification Methods	affinity chromatography technology, enzymatic study, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0034976 - response to endoplasmic reticulum stress GO:0061709 - reticulophagy GO:0071569 - protein ufmylation GO:1990592 - protein K69-linked ufmylation
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 404 Hs			1 167
+	Ce
		954483 UBA5_CAEEL (4-403): 1.22e-118: 352: 57.59		UFC1_CAEEL (3-162): 1.3e-105: 300: 71.88