HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: GRIA2 (P42262)
Glutamate receptor 2 (GluR-2) (AMPA-selective glutamate receptor 2) (GluR-B) (GluR-K2) (Glutamate receptor ionotropic, AMPA 2)
Gene: GRIA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	11891216
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 883
+	Rn
		585184 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRIA2_RAT (1-883): 0: 919: 99.55
+	Hs
		132765 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIA3_HUMAN (2-883): 0: 880: 71.46
+	Rn
		585196 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRIA3_RAT (2-883): 0: 877: 71.57
+	Hs
		132763 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIA1_HUMAN (4-862): 0: 862: 70.55
+	Hs
		132771 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIA4_HUMAN (1-860): 0: 852: 72.40
+	Rn
		585157 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRIA1_RAT (4-862): 0: 858: 70.21
+	Rn
		585219 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRIA4_RAT (1-860): 0: 855: 73.33
+	Hs
		132839 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIK2_HUMAN (2-849): 0: 791: 38.78
+	Hs
		132760 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		GRIK1_HUMAN (11-880): 0: 778: 36.55
+	Rn
		611608 SDCB1_RAT (1-298): 2.61e-101: 300: 89.33		GRIK1_RAT (11-853): 0: 765: 37.54
+	Mm
		620904 DLG2_MOUSE (6-268): 1.74e-19: 90.6: 15.93		GRIA1_MOUSE (4-862): 0: 855: 69.28
+	Mm
		620881 DLG3_MOUSE (184-268): 2.19e-17: 84.4: 26.09		GRIA1_MOUSE (4-862): 0: 855: 69.28
+	Hs
		1022366 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		GRIK2_HUMAN (2-849): 0: 791: 38.78
+	Hs
		1081918 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		GRIK5_HUMAN (4-864): 0: 664: 34.09
+	Rn
		1143996 DLG2_RAT (6-268): 2.34e-19: 90.2: 15.93		GRID1_RAT (4-858): 0: 591: 27.38
+	Rn
		1144131 DLG2_RAT (6-268): 2.34e-19: 90.2: 15.93		GRID2_RAT (1-867): 0: 591: 26.21
+	Mm
		723606 DLG2_MOUSE (6-268): 1.74e-19: 90.6: 15.93		NMDZ1_MOUSE (1-868): 0: 571: 22.16
+	Hs
		1028140 DLG2_HUMAN (6-268): 7.88e-20: 91.4: 15.19		NMDE2_HUMAN (5-845): 0: 569: 22.47
+	Mm
		723568 DLG3_MOUSE (184-268): 2.19e-17: 84.4: 26.09		NMDZ1_MOUSE (1-868): 0: 571: 22.16
+	Hs
		1028145 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		NMDE2_HUMAN (5-845): 0: 569: 22.47