HitPredict

Interactor 1: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Interactor 2: EPC1 (Q9H2F5)
Enhancer of polycomb homolog 1
Gene: EPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

The method score is based on:

Property	Details
Experiments	31753913, 27153538, 36066422
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0035267 - NuA4 histone acetyltransferase complex GO:0042981 - regulation of apoptotic process and 5 others more... GO:0045893 - positive regulation of DNA-templated transcription GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0051726 - regulation of cell cycle GO:1905168 - positive regulation of double-strand break repair via homologous recombination GO:2000779 - regulation of double-strand break repair
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	1235
Hs

1	836

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024