HitPredict - High confidence protein-protein interactions

Interactor 1: BC11A (Q9H165)
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)
Gene: BCL11A

Interactor 2: BC11A (Q9H165)
B-cell lymphoma/leukemia 11A (BCL-11A) (B-cell CLL/lymphoma 11A) (COUP-TF-interacting protein 1) (Ecotropic viral integration site 9 protein homolog) (EVI-9) (Zinc finger protein 856)
Gene: BCL11A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.58	1.00	0.768

Property	Details
Experiments	12196208, 16704730
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	zf-C2H2~zf-C2H2
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001067 - transcription regulatory region nucleic acid binding GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific GO:0003700 - DNA-binding transcription factor activity and 30 others more... GO:0003712 - transcription coregulator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0006357 - regulation of transcription by RNA polymerase II GO:0010628 - positive regulation of gene expression GO:0010976 - positive regulation of neuron projection development GO:0010977 - negative regulation of neuron projection development GO:0016363 - nuclear matrix GO:0016514 - SWI/SNF complex GO:0016925 - protein sumoylation GO:0019901 - protein kinase binding GO:0030517 - negative regulation of axon extension GO:0032463 - negative regulation of protein homooligomerization GO:0042382 - paraspeckles GO:0042803 - protein homodimerization activity GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding GO:0046982 - protein heterodimerization activity GO:0048671 - negative regulation of collateral sprouting GO:0048672 - positive regulation of collateral sprouting GO:0050773 - regulation of dendrite development GO:0098794 - postsynapse GO:0140297 - DNA-binding transcription factor binding GO:1903860 - negative regulation of dendrite extension GO:1904800 - negative regulation of neuron remodeling GO:1905232 - cellular response to L-glutamate GO:2000171 - negative regulation of dendrite development GO:2000173 - negative regulation of branching morphogenesis of a nerve
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1	835
Hs

1	835

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Last updated: 15 Jul 2024