Interactor 1: ZBP1 (Q9H171)
Z-DNA-binding protein 1 (DNA-dependent activator of IFN-regulatory factors) (DAI) (Tumor stroma and activated macrophage protein DLM-1)
Gene: ZBP1

Interactor 2: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.77 1.00 0.878

The method score is based on:

Property Details
Experiments 888800001028, 36268590, 36650286, 19590578
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RHIM~RHIM
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0051607 - defense response to virus
GO:0060545 - positive regulation of necroptotic process
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 429
Hs

1 518
+ Mm
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024