HitPredict

Interactor 1: SDCB1 (O00560)
Syntenin-1 (Melanoma differentiation-associated protein 9) (MDA-9) (Pro-TGF-alpha cytoplasmic domain-interacting protein 18) (TACIP18) (Scaffold protein Pbp1) (Syndecan-binding protein 1)
Gene: SDCBP

Interactor 2: RHOH (Q15669)
Rho-related GTP-binding protein RhoH (GTP-binding protein TTF) (Translocation three four protein)
Gene: RHOH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005737 - cytoplasm GO:0005856 - cytoskeleton GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 298 Hs			1 191
+	Hs
		132717 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Hs
		132812 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		132816 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		132739 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		132805 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		132735 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC2_HUMAN (2-191): 1.96e-72: 218: 38.07
+	Hs
		132804 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		132808 SDCB1_HUMAN (1-298): 8.79e-106: 311: 100.00		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Hs
		925382 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RAC1_HUMAN (2-191): 2.63e-75: 226: 39.09
+	Hs
		894155 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		CDC42_HUMAN (2-181): 1.52e-73: 221: 42.25
+	Hs
		951099 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		900616 PREX2_HUMAN (108-256): 2.7e-39: 148: 20.40		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Hs
		915880 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOB_HUMAN (6-191): 6.57e-85: 250: 40.93
+	Hs
		436297 SCRIB_HUMAN (161-276): 6.09e-16: 80.2: 18.61		RHOC_HUMAN (6-185): 6.48e-85: 250: 42.25
+	Mm
		925797 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		RAC1_MOUSE (2-191): 2.63e-75: 226: 39.09
+	Hs
		564636 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOQ_HUMAN (5-190): 8.15e-74: 222: 39.49
+	Hs
		892525 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RAC3_HUMAN (2-171): 3.86e-72: 218: 41.81
+	Hs
		951207 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOG_HUMAN (2-191): 2.32e-71: 216: 37.56
+	Hs
		900762 DLG3_HUMAN (184-268): 1.4e-17: 84.8: 26.09		RHOA_HUMAN (6-191): 8.9e-71: 214: 39.38
+	Mm
		1111996 DLG4_MOUSE (193-286): 2.27e-16: 81.4: 24.75		Q3TLP8_MOUSE (2-191): 9.76e-71: 215: 36.11