HitPredict

Interactor 1: P2Y12 (Q9H244)
P2Y purinoceptor 12 (P2Y12) (ADP-glucose receptor) (ADPG-R) (P2T(AC)) (P2Y(AC)) (P2Y(cyc)) (P2Y12 platelet ADP receptor) (P2Y(ADP)) (SP1999)
Gene: P2RY12

Interactor 2: TNPO3 (Q9Y5L0)
Transportin-3 (Importin-12) (Imp12) (Transportin-SR) (TRN-SR)
Gene: TNPO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 342 Hs			1 923
+	Hs
		782494 P2RY2_HUMAN (17-304): 1.23e-71: 228: 24.22		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		723121 OPRM_HUMAN (4-339): 3.47e-65: 212: 23.75		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		1031125 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		TNPO3_HUMAN (1-923): 0: 657: 100.00
+	Hs
		163184 LPAR4_HUMAN (7-309): 9.77e-89: 272: 26.56		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		162445 APJ_HUMAN (1-340): 9.92e-70: 224: 22.16		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		162701 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		XPO1_HUMAN (3-920): 6.76e-151: 475: 12.37
+	Hs
		297159 OPRM_HUMAN (4-339): 3.47e-65: 212: 23.75		IPO13_HUMAN (5-923): 2.1e-143: 452: 21.02
+	Hs
		297173 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		IPO13_HUMAN (5-923): 2.1e-143: 452: 21.02
+	Hs
		155548 LPAR6_HUMAN (13-310): 6.58e-88: 269: 26.49		TNPO2_HUMAN (68-784): 3.33e-92: 313: 12.26
+	Hs
		297166 PAR2_HUMAN (22-315): 3.79e-25: 106: 26.42		IPO13_HUMAN (5-923): 2.1e-143: 452: 21.02
+	Hs
		178124 P2RY2_HUMAN (17-304): 1.23e-71: 228: 24.22		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		178120 APJ_HUMAN (1-340): 9.92e-70: 224: 22.16		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		207933 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		XPOT_HUMAN (12-770): 1.76e-93: 318: 15.10
+	Hs
		155568 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		TNPO2_HUMAN (68-784): 3.33e-92: 313: 12.26
+	Hs
		178157 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		155556 PAR2_HUMAN (22-315): 3.79e-25: 106: 26.42		TNPO2_HUMAN (68-784): 3.33e-92: 313: 12.26
+	Hs
		178136 PAR2_HUMAN (22-315): 3.79e-25: 106: 26.42		IPO8_HUMAN (10-813): 5.2e-89: 307: 9.92
+	Hs
		723407 APJ_HUMAN (1-340): 9.92e-70: 224: 22.16		XPO5_HUMAN (9-614): 3.04e-22: 105: 14.21
+	Hs
		1031082 GPR17_HUMAN (6-333): 1.6e-63: 207: 24.01		XPO5_HUMAN (9-614): 3.04e-22: 105: 14.21
+	Hs
		876199 PAR2_HUMAN (22-315): 3.79e-25: 106: 26.42		XPO5_HUMAN (9-614): 3.04e-22: 105: 14.21