HitPredict

Interactor 1: SPTN4 (Q9H254)
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)
Gene: SPTBN4

Interactor 2: CHM4B (Q9H444)
Charged multivesicular body protein 4b (Chromatin-modifying protein 4b) (CHMP4b) (SNF7 homolog associated with Alix 1) (SNF7-2) (hSnf7-2) (Vacuolar protein sorting-associated protein 32-2) (Vps32-2) (hVps32-2)
Gene: CHMP4B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2564 Hs			1 224
+	Hs
		1286695 SPTN4_HUMAN (1-2564): 0: 732: 100.00		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		211663 ACTN4_HUMAN (60-639): 2.57e-113: 386: 39.93		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		211642 ACTN4_HUMAN (60-639): 2.57e-113: 386: 39.93		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		725696 ACTN2_HUMAN (60-648): 9.1e-110: 375: 39.41		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		725686 ACTN2_HUMAN (60-648): 9.1e-110: 375: 39.41		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		963414 SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		963386 SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		164664 SPTN2_HUMAN (507-2546): 2.8e-51: 203: 18.94		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		164653 SPTN2_HUMAN (507-2546): 2.8e-51: 203: 18.94		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1045516 SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		1045480 SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		506841 SPTB1_HUMAN (1693-2459): 1.21e-17: 92.9: 11.98		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		1068664 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		506831 SPTB1_HUMAN (1693-2459): 1.21e-17: 92.9: 11.98		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		521612 ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		521595 ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		993293 ACTN3_HUMAN (1817-2273): 1.6e-10: 69: 12.85		CHM4B_HUMAN (1-224): 3.19e-52: 169: 100.00
+	Hs
		993280 ACTN3_HUMAN (1817-2273): 1.6e-10: 69: 12.85		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78
+	Hs
		1286754 MACF1_HUMAN (887-1821): 3.14e-10: 68.7: 13.90		CHM4C_HUMAN (1-221): 1.06e-47: 158: 60.78