Protein: GPR21
Probable G-protein coupled receptor 21

Gene: GPR21
Organism: Homo sapiens
Interactions: 81
UniProt ID: Q99679

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0008286 - insulin receptor signaling pathway
GO:0040018 - positive regulation of multicellular organism growth
GO:0042593 - glucose homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1268637

LPAR1
Lysophosphatidic acid receptor 1

2

20

High-throughput

0.811

High

1305566

S1PR5
Sphingosine 1-phosphate receptor 5

2

19

High-throughput

0.811

High

1261845

BT2A2
Butyrophilin subfamily 2 member A2

2

0

High-throughput

0.770

High

1294894

TXD15
Thioredoxin domain-containing protein 15

2

2

High-throughput

0.726

High

895718

CXCR4
C-X-C chemokine receptor type 4

1

18

High-throughput

0.691

High

1040084

MTR1L
Melatonin-related receptor

1

18

High-throughput

0.691

High

1305563

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

2

High-throughput

0.691

High

235414

ADCY9
Adenylate cyclase type 9

2

1

High-throughput

0.628

High

300361

AGRL1
Adhesion G protein-coupled receptor L1

2

3

High-throughput

0.628

High

313951

PIGN
GPI ethanolamine phosphate transferase 1

2

3

High-throughput

0.628

High

392720

B3A2
Anion exchange protein 2

2

3

High-throughput

0.628

High

415464

ATPB
ATP synthase subunit beta, mitochondrial

2

6

High-throughput

0.628

High

475154

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

7

High-throughput

0.628

High

567237

CXA1
Gap junction alpha-1 protein

2

7

High-throughput

0.628

High

573878

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

5

High-throughput

0.628

High

1035223

FZD5
Frizzled-5

2

3

High-throughput

0.628

High

1053387

FZD2
Frizzled-2

2

3

High-throughput

0.628

High

1079498

KCNJ8
ATP-sensitive inward rectifier potassium channel 8

2

3

High-throughput

0.628

High

1117488

ANO6
Anoctamin-6

2

2

High-throughput

0.628

High

1193315

T179B
Transmembrane protein 179B

2

1

High-throughput

0.628

High

1239531

AT11C
Phospholipid-transporting ATPase IG

2

3

High-throughput

0.628

High

1271582

EDA
Ectodysplasin-A

2

2

High-throughput

0.628

High

1291351

S47A1
Multidrug and toxin extrusion protein 1

2

1

High-throughput

0.628

High

1305562

S29A1
Equilibrative nucleoside transporter 1

2

1

High-throughput

0.628

High

1305564

S12A9
Solute carrier family 12 member 9

2

8

High-throughput

0.628

High

1305565

ZDHC5
Palmitoyltransferase ZDHHC5

2

5

High-throughput

0.628

High

1305570

FZD3
Frizzled-3

2

3

High-throughput

0.628

High

1305573

CNNM1
Metal transporter CNNM1

2

1

High-throughput

0.628

High

1305575

S12A6
Solute carrier family 12 member 6

2

8

High-throughput

0.628

High

1305576

S12A4
Solute carrier family 12 member 4

2

8

High-throughput

0.628

High

1305582

S12A7
Solute carrier family 12 member 7

2

8

High-throughput

0.628

High

1016017

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

4

High-throughput

0.618

High

240907

S19A2
Thiamine transporter 1

2

0

High-throughput

0.602

High

277450

DGAT1
Diacylglycerol O-acyltransferase 1

2

0

High-throughput

0.602

High

1132958

CSCL2
CSC1-like protein 2

2

0

High-throughput

0.602

High

1235869

S15A4
Solute carrier family 15 member 4

2

0

High-throughput

0.602

High

1239947

SIDT2
SID1 transmembrane family member 2

2

0

High-throughput

0.602

High

1305569

VEZA
Vezatin

2

0

High-throughput

0.602

High

231884

MARH6
E3 ubiquitin-protein ligase MARCHF6

2

1

High-throughput

0.574

High

234139

FADS1
Acyl-CoA

2

1

High-throughput

0.574

High

237836

TSN3
Tetraspanin-3

2

10

High-throughput

0.574

High

371284

ATP8
ATP synthase protein 8

2

1

High-throughput

0.574

High

623342

AT5F1
ATP synthase F(0) complex subunit B1, mitochondrial

2

2

High-throughput

0.574

High

946431

EREP3
Protein ENTREP3

2

1

High-throughput

0.574

High

1068338

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

2

High-throughput

0.574

High

1078484

TOM34
Mitochondrial import receptor subunit TOM34

2

2

High-throughput

0.574

High

1109903

HSDL1
Inactive hydroxysteroid dehydrogenase-like protein 1

2

1

High-throughput

0.574

High

1137297

TM164
Transmembrane protein 164

2

1

High-throughput

0.574

High

1168251

CERS6
Ceramide synthase 6

2

5

High-throughput

0.574

High

1187522

ERMP1
Endoplasmic reticulum metallopeptidase 1

2

4

High-throughput

0.574

High

1202359

RETR3
Reticulophagy regulator 3

2

3

High-throughput

0.574

High

1236157

FITM2
Acyl-coenzyme A diphosphatase FITM2

2

1

High-throughput

0.574

High

1245950

MFSD8
Major facilitator superfamily domain-containing protein 8

2

4

High-throughput

0.574

High

1261703

LMBR1
Limb region 1 protein homolog

2

2

High-throughput

0.574

High

1298158

TLCD4
TLC domain-containing protein 4

2

1

High-throughput

0.574

High

1298468

MBOA7
Lysophospholipid acyltransferase 7

2

5

High-throughput

0.574

High

1305574

ELOV2
Very long chain fatty acid elongase 2

2

3

High-throughput

0.574

High

1305578

ZDHC9
Palmitoyltransferase ZDHHC9

2

4

High-throughput

0.574

High

1305580

RHBD3
Rhomboid domain-containing protein 3

2

3

High-throughput

0.574

High

526529

GP1BB
Platelet glycoprotein Ib beta chain

1

2

High-throughput

0.536

High

637033

ATPA
ATP synthase subunit alpha, mitochondrial

1

6

High-throughput

0.536

High

681208

SC6A6
Sodium- and chloride-dependent taurine transporter

1

3

High-throughput

0.536

High

474531

GPHRB
Golgi pH regulator B

2

7

High-throughput

0.533

High

1305568

XKR8
XK-related protein 8

1

0

High-throughput

0.513

High

81836

GPHRA
Golgi pH regulator A

2

7

High-throughput

0.504

High

1305571

AT132
Polyamine-transporting ATPase 13A2

1

20

Small-scale

0.494

High

1119218

MBRL
Membralin

1

2

High-throughput

0.489

High

1151559

IPIL1
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 1

1

1

High-throughput

0.489

High

1165409

LCLT1
Lysocardiolipin acyltransferase 1

1

4

High-throughput

0.489

High

1269063

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

1

High-throughput

0.489

High

1305579

PTH2
Peptidyl-tRNA hydrolase 2, mitochondrial

1

1

High-throughput

0.489

High

1299177

MIA2
Melanoma inhibitory activity protein 2

1

4

High-throughput

0.407

High

49362

T120B
Transmembrane protein 120B

2

0

High-throughput

0.328

High

276481

FACE1
CAAX prenyl protease 1 homolog

2

0

High-throughput

0.328

High

279972

ATP5L
ATP synthase subunit g, mitochondrial

2

0

High-throughput

0.328

High

1185436

OTU6A
OTU domain-containing protein 6A

2

0

High-throughput

0.328

High

1305567

SG196
Protein O-mannose kinase

2

0

High-throughput

0.328

High

1305572

ST7
Suppressor of tumorigenicity 7 protein

2

0

High-throughput

0.328

High

1305577

CIA30
Complex I intermediate-associated protein 30, mitochondrial

2

0

High-throughput

0.328

High

613008

TCEA1
Transcription elongation factor A protein 1

1

0

High-throughput

0.279

Low

1305581

T184B
Transmembrane protein 184B

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024