HitPredict

Interactor 1: SPTN4 (Q9H254)
Spectrin beta chain, non-erythrocytic 4 (Beta-IV spectrin) (Spectrin, non-erythroid beta chain 3)
Gene: SPTBN4

Interactor 2: ECT2 (Q9H8V3)
Protein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene: ECT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2564 Hs			1 914
+	Hs
		211665 ACTN4_HUMAN (60-639): 2.57e-113: 386: 39.93		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		725699 ACTN2_HUMAN (60-648): 9.1e-110: 375: 39.41		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		963418 SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		164666 SPTN2_HUMAN (507-2546): 2.8e-51: 203: 18.94		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1045521 SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		506843 SPTB1_HUMAN (1693-2459): 1.21e-17: 92.9: 11.98		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1068667 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		521615 ACTN1_HUMAN (1813-2273): 3.24e-14: 80.9: 10.24		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		993295 ACTN3_HUMAN (1817-2273): 1.6e-10: 69: 12.85		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		1333811 MACF1_HUMAN (887-1821): 3.14e-10: 68.7: 13.90		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		974147 DYST_HUMAN (971-1734): 2.66e-10: 68.7: 12.78		ECT2_HUMAN (1-914): 0: 886: 100.00
+	Hs
		963335 SPTB2_HUMAN (624-2551): 4.56e-61: 235: 17.42		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		1045423 SPTN1_HUMAN (259-1728): 1.07e-47: 191: 15.07		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		1068638 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		FGD4_HUMAN (312-858): 1.12e-81: 281: 18.53
+	Hs
		1068677 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		ARHG4_HUMAN (350-880): 1.39e-79: 274: 17.20
+	Hs
		548710 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		VAV_HUMAN (390-707): 1.61e-76: 269: 21.82
+	Hs
		1068630 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		Q96D37_HUMAN (390-707): 1.05e-76: 268: 21.82
+	Hs
		974083 DYST_HUMAN (971-1734): 2.66e-10: 68.7: 12.78		ITSN1_HUMAN (402-782): 1.02e-76: 276: 18.14
+	Hs
		962561 PLEC_HUMAN (233-1186): 4.07e-17: 91.3: 11.29		ECT2L_HUMAN (453-721): 2.8e-23: 108: 28.93
+	Hs
		506544 UTRN_HUMAN (212-2049): 2.24e-15: 85.6: 10.34		BCR_HUMAN (453-641): 1.17e-14: 80.9: 27.69