HitPredict

Interactor 1: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Interactor 2: DTL (Q9NZJ0)
Denticleless protein homolog (DDB1- and CUL4-associated factor 2) (Lethal(2) denticleless protein homolog) (Retinoic acid-regulated nuclear matrix-associated protein)
Gene: DTL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~WD40
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 779 Hs			1 730
+	Hs
		903516 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		1288303 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		SNR40_HUMAN (258-581): 7.14e-39: 149: 13.90
+	Hs
		793030 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		LIS1_HUMAN (260-499): 2.94e-36: 143: 15.23
+	Hs
		236256 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		PRP17_HUMAN (16-169): 9.6e-20: 95.8: 16.97
+	Hs
		1331436 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		NLE1_HUMAN (343-590): 4e-15: 80.5: 10.97
+	Hs
		1325948 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		WDR12_HUMAN (227-403): 1.54e-14: 78.4: 20.00
+	Hs
		1309164 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TBL1Y_HUMAN (345-587): 1.16e-12: 73.2: 12.95
+	Hs
		1318178 PKHA4_HUMAN (1-779): 4.1e-157: 477: 100.00		TBL1R_HUMAN (345-620): 1.5e-12: 72.8: 11.68
+	Hs
		1153322 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		FBXW7_HUMAN (175-521): 4.51e-54: 200: 12.16
+	Hs
		903302 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		WDR5_HUMAN (11-243): 2.2e-54: 192: 13.95
+	Hs
		1167395 MPRIP_HUMAN (2-499): 4.76e-44: 173: 16.57		FBXW7_HUMAN (175-521): 4.51e-54: 200: 12.16
+	Hs
		1148943 CYTSA_HUMAN (320-643): 3.92e-43: 171: 12.81		FBXW7_HUMAN (175-521): 4.51e-54: 200: 12.16
+	Hs
		1240465 PKHA5_HUMAN (2-653): 1.62e-36: 150: 17.61		POC1A_HUMAN (256-429): 6.94e-28: 118: 24.71
+	Hs
		1153371 PKHA7_HUMAN (2-440): 4.98e-50: 192: 28.02		TBL1R_HUMAN (345-620): 1.5e-12: 72.8: 11.68