HitPredict

Interactor 1: QSOX1 (O00391)
Sulfhydryl oxidase 1 (hQSOX) (EC 1.8.3.2) (Quiescin Q6)
Gene: QSOX1

Interactor 2: FNDC5 (Q8NAU1)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) [Cleaved into: Irisin]
Gene: FNDC5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005576 - extracellular region
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 747 Hs			1 260
+	Mm
		1189523 QSOX2_MOUSE (2-613): 3.8e-160: 481: 39.65		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23
+	Mm
		1317522 TXND5_MOUSE (10-269): 1.27e-44: 167: 20.21		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23
+	Mm
		1317564 PDIA6_MOUSE (30-305): 1.5e-41: 159: 17.87		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23
+	Mm
		697730 PDIA3_MOUSE (37-163): 4.55e-27: 117: 22.84		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23
+	Mm
		1317796 DJC10_MOUSE (91-445): 8.84e-21: 99.6: 10.05		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23
+	Mm
		464497 PDIA4_MOUSE (488-596): 4.37e-11: 68.4: 13.39		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23
+	Mm
		479097 PDIA1_MOUSE (488-567): 8.06e-09: 60.7: 10.00		FNDC5_MOUSE (1-260): 3.72e-159: 443: 89.23