HitPredict

Interactor 1: MED20 (Q9H944)
Mediator of RNA polymerase II transcription subunit 20 (Mediator complex subunit 20) (TRF-proximal protein homolog) (hTRFP)
Gene: MED20

Interactor 2: MED16 (Q9Y2X0)
Mediator of RNA polymerase II transcription subunit 16 (Mediator complex subunit 16) (Thyroid hormone receptor-associated protein 5) (Thyroid hormone receptor-associated protein complex 95 kDa component) (Trap95) (Vitamin D3 receptor-interacting protein complex 92 kDa component) (DRIP92)
Gene: MED16

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

The method score is based on:

Property	Details
Experiments	25281560, 24981860, 33961781, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003713 - transcription coactivator activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006357 - regulation of transcription by RNA polymerase II GO:0006366 - transcription by RNA polymerase II and 5 others more... GO:0016592 - mediator complex GO:0032968 - positive regulation of transcription elongation by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II GO:0070847 - core mediator complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	212
Hs

1	877

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024