Protein: DHB13
17-beta-hydroxysteroid dehydrogenase 13 (17-beta-HSD 13) (EC 1.1.1.-) (EC 1.1.1.62) (Hepatic retinol/retinal dehydrogenase) (EC 1.1.1.105) (Short chain dehydrogenase/reductase family 16C member 3) (Short-chain dehydrogenase/reductase 9)

Gene: DHB13, HSD17B13
Organism: Homo sapiens
Interactions: 141
UniProt ID: Q7Z5P4

Gene Ontology (top 5):
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0004745 - all-trans-retinol dehydrogenase (NAD+) activity
GO:0005783 - endoplasmic reticulum
GO:0005811 - lipid droplet
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

122621

UBXN8
UBX domain-containing protein 8

2

3

High-throughput

0.606

High

144447

SCD
Stearoyl-CoA desaturase

2

3

High-throughput

0.606

High

160295

GOSR2
Golgi SNAP receptor complex member 2

2

1

High-throughput

0.606

High

333072

VAPB
Vesicle-associated membrane protein-associated protein B/C

2

8

High-throughput

0.606

High

360026

NB5R3
NADH-cytochrome b5 reductase 3

2

2

High-throughput

0.606

High

989348

VAMP2
Vesicle-associated membrane protein 2

2

8

High-throughput

0.606

High

1050033

PLP2
Proteolipid protein 2

2

4

High-throughput

0.606

High

1097817

STX5
Syntaxin-5

2

4

High-throughput

0.606

High

1139214

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

2

High-throughput

0.606

High

1142865

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

1

High-throughput

0.606

High

1203704

TTMP
TPA-induced transmembrane protein

2

3

High-throughput

0.606

High

1219284

ECM29
Proteasome adapter and scaffold protein ECM29

2

2

High-throughput

0.606

High

1272611

PCAT2
Lysophosphatidylcholine acyltransferase 2

2

6

High-throughput

0.606

High

1279327

ORML3
ORM1-like protein 3

2

1

High-throughput

0.606

High

1279329

JAGN1
Protein jagunal homolog 1

2

2

High-throughput

0.606

High

1279340

S35B4
Nucleotide sugar transporter SLC35B4

2

2

High-throughput

0.606

High

1279341

TM203
Transmembrane protein 203

2

1

High-throughput

0.606

High

1279350

REEP6
Receptor expression-enhancing protein 6

2

4

High-throughput

0.606

High

1279358

CYBC1
Cytochrome b-245 chaperone 1

2

1

High-throughput

0.606

High

1279359

YIPF4
Protein YIPF4

2

2

High-throughput

0.606

High

1279363

TACAN
Transmembrane protein 120A

2

3

High-throughput

0.606

High

1279367

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

5

High-throughput

0.606

High

1279371

DBLOH
Diablo IAP-binding mitochondrial protein

2

1

High-throughput

0.606

High

1279373

PLCD
1-acyl-sn-glycerol-3-phosphate acyltransferase delta

2

9

High-throughput

0.606

High

1279374

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

2

9

High-throughput

0.606

High

1279377

SAC1
Phosphatidylinositol-3-phosphatase SAC1

2

2

High-throughput

0.606

High

1279386

VAPA
Vesicle-associated membrane protein-associated protein A

2

8

High-throughput

0.606

High

1279398

SERP1
Stress-associated endoplasmic reticulum protein 1

2

1

High-throughput

0.606

High

1279366

TSN10
Tetraspanin-10

3

6

High-throughput

0.599

High

253089

PLIN3
Perilipin-3

2

0

High-throughput

0.580

High

331494

LRAT
Lecithin retinol acyltransferase

2

0

High-throughput

0.580

High

387533

APOA2
Apolipoprotein A-II

2

0

High-throughput

0.580

High

688394

PPLA
Phospholamban

2

0

High-throughput

0.580

High

894425

MMP14
Matrix metalloproteinase-14

2

0

High-throughput

0.580

High

1164217

AOC3
Amine oxidase [copper-containing] 3

2

0

High-throughput

0.580

High

1203114

SGMR2
Sigma intracellular receptor 2

2

0

High-throughput

0.580

High

1279339

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.580

High

1279376

TREX1
Three-prime repair exonuclease 1

2

0

High-throughput

0.580

High

1279380

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

1279382

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

High-throughput

0.580

High

1279384

SPG21
Maspardin

2

0

High-throughput

0.580

High

1279397

INSI2
Insulin-induced gene 2 protein

2

0

High-throughput

0.580

High

154494

CLD4
Claudin-4

2

2

High-throughput

0.553

High

189665

STX7
Syntaxin-7

2

2

High-throughput

0.553

High

280235

SC22B
Vesicle-trafficking protein SEC22b

2

3

High-throughput

0.553

High

339223

SFT2B
Vesicle transport protein SFT2B

2

1

High-throughput

0.553

High

350384

ABHGA
Phosphatidylserine lipase ABHD16A

2

1

High-throughput

0.553

High

438089

GLPB
Glycophorin-B

2

1

High-throughput

0.553

High

539478

ITAM
Integrin alpha-M

2

1

High-throughput

0.553

High

549453

CD20
B-lymphocyte antigen CD20

2

1

High-throughput

0.553

High

706034

CXB2
Gap junction beta-2 protein

2

2

High-throughput

0.553

High

849013

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

4

High-throughput

0.553

High

928863

LIPR1
Inactive pancreatic lipase-related protein 1

2

2

High-throughput

0.553

High

1005396

CP4F2
Cytochrome P450 4F2

2

1

High-throughput

0.553

High

1006967

CLD10
Claudin-10

2

2

High-throughput

0.553

High

1200097

UNC50
Protein unc-50 homolog

2

1

High-throughput

0.553

High

1229428

TMM42
Transmembrane protein 42

2

1

High-throughput

0.553

High

1234014

S35E4
Solute carrier family 35 member E4

2

1

High-throughput

0.553

High

1245867

BRID5
BRICHOS domain-containing protein 5

2

1

High-throughput

0.553

High

1256654

TPRG1
Tumor protein p63-regulated gene 1 protein

2

1

High-throughput

0.553

High

1279325

ANR46
Ankyrin repeat domain-containing protein 46

2

3

High-throughput

0.553

High

1279331

CLD19
Claudin-19

2

2

High-throughput

0.553

High

1279336

SCAM5
Secretory carrier-associated membrane protein 5

2

3

High-throughput

0.553

High

1279343

S2546
Mitochondrial outer membrane protein SLC25A46

2

1

High-throughput

0.553

High

1279346

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

2

1

High-throughput

0.553

High

1279347

CKLF7
CKLF-like MARVEL transmembrane domain-containing protein 7

2

4

High-throughput

0.553

High

1279348

RUSF1
RUS family member 1

2

1

High-throughput

0.553

High

1279352

SIAT2
Beta-galactoside alpha-2,6-sialyltransferase 2

2

1

High-throughput

0.553

High

1279353

SFXN2
Sideroflexin-2

2

3

High-throughput

0.553

High

1279357

ZNT3
Probable proton-coupled zinc antiporter SLC30A3

2

6

High-throughput

0.553

High

1279361

SFXN3
Sideroflexin-3

2

3

High-throughput

0.553

High

1279368

TMM60
Transmembrane protein 60

2

1

High-throughput

0.553

High

1279369

SFXN1
Sideroflexin-1

2

3

High-throughput

0.553

High

1279372

KISHB
Protein kish-B

2

1

High-throughput

0.553

High

1279387

TM14C
Transmembrane protein 14C

2

2

High-throughput

0.553

High

1279391

AGRE2
Adhesion G protein-coupled receptor E2

2

1

High-throughput

0.553

High

1279392

PRAF1
Prenylated Rab acceptor protein 1

2

2

High-throughput

0.553

High

1279394

THS7A
Thrombospondin type-1 domain-containing protein 7A [Cleaved into: Thrombospondin type-1 domain-containing protein 7A, soluble form]

2

1

High-throughput

0.553

High

1279396

TMX2
Thioredoxin-related transmembrane protein 2

2

3

High-throughput

0.553

High

884661

SYHM
Histidine--tRNA ligase, mitochondrial

1

2

High-throughput

0.536

High

959351

RAP1B
Ras-related protein Rap-1b

1

14

High-throughput

0.536

High

1279355

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

4

High-throughput

0.536

High

1279383

P4HTM
Transmembrane prolyl 4-hydroxylase

1

2

High-throughput

0.536

High

1279395

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

4

High-throughput

0.536

High

2840

A0A0C4DFN3
Monoglyceride lipase

1

3

High-throughput

0.515

High

1149438

SKI2
Superkiller complex protein 2

1

0

High-throughput

0.513

High

1270878

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.501

High

1279393

XPO7
Exportin-7

1

2

High-throughput

0.489

High

1154663

VAMP3
Vesicle-associated membrane protein 3

1

7

High-throughput

0.481

High

1279332

SERP2
Stress-associated endoplasmic reticulum protein 2

1

1

High-throughput

0.481

High

1279356

MGLL
Monoglyceride lipase

1

3

High-throughput

0.481

High

284586

ECI2
Enoyl-CoA delta isomerase 2

1

3

High-throughput

0.479

High

1279344

Q96AL5
PBX3 protein

1

1

High-throughput

0.470

High

49663

T120B
Transmembrane protein 120B

1

3

High-throughput

0.439

High

278521

VAMP4
Vesicle-associated membrane protein 4

1

6

High-throughput

0.439

High

328688

VAMP5
Vesicle-associated membrane protein 5

1

7

High-throughput

0.439

High

335561

BMP10
Bone morphogenetic protein 10

1

1

High-throughput

0.439

High

823957

PBX3
Pre-B-cell leukemia transcription factor 3

1

1

High-throughput

0.439

High

1203315

TM128
Transmembrane protein 128

1

1

High-throughput

0.439

High

1207706

TMM31
Transmembrane protein 31

1

1

High-throughput

0.439

High

1279378

TM14B
Transmembrane protein 14B

1

2

High-throughput

0.439

High

1279388

LPAR3
Lysophosphatidic acid receptor 3

1

9

High-throughput

0.439

High

74172

SMIM1
Small integral membrane protein 1

2

0

High-throughput

0.316

High

162220

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

2

0

High-throughput

0.316

High

168103

TIM23
Mitochondrial import inner membrane translocase subunit Tim23

2

0

High-throughput

0.316

High

281473

MSPD3
Motile sperm domain-containing protein 3

2

0

High-throughput

0.316

High

390909

TRFE
Serotransferrin

2

0

High-throughput

0.316

High

665989

IBP5
Insulin-like growth factor-binding protein 5

2

0

High-throughput

0.316

High

692218

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

0

High-throughput

0.316

High

1055126

CCG1
Voltage-dependent calcium channel gamma-1 subunit

2

0

High-throughput

0.316

High

1122473

SREC
Scavenger receptor class F member 1

2

0

High-throughput

0.316

High

1209022

CAHM6
Calcium homeostasis modulator protein 6

2

0

High-throughput

0.316

High

1236203

MFSD5
Molybdate-anion transporter

2

0

High-throughput

0.316

High

1247359

ATRAP
Type-1 angiotensin II receptor-associated protein

2

0

High-throughput

0.316

High

1249524

SNORC
Protein SNORC

2

0

High-throughput

0.316

High

1279326

NRM
Nurim

2

0

High-throughput

0.316

High

1279330

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

1279333

T229B
Transmembrane protein 229B

2

0

High-throughput

0.316

High

1279334

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.316

High

1279335

CLDN2
Claudin domain-containing protein 2

2

0

High-throughput

0.316

High

1279338

T255B
Transmembrane protein 255B

2

0

High-throughput

0.316

High

1279342

FAKD4
FAST kinase domain-containing protein 4

2

0

High-throughput

0.316

High

1279345

MID49
Mitochondrial dynamics protein MID49

2

0

High-throughput

0.316

High

1279349

TMM19
Transmembrane protein 19

2

0

High-throughput

0.316

High

1279351

FXDC2
Fatty acid hydroxylase domain-containing protein 2

2

0

High-throughput

0.316

High

1279354

BBC3B
Bcl-2-binding component 3, isoforms 3/4

2

0

High-throughput

0.316

High

1279360

TM243
Transmembrane protein 243

2

0

High-throughput

0.316

High

1279362

YIPF2
Protein YIPF2

2

0

High-throughput

0.316

High

1279364

TM222
Transmembrane protein 222

2

0

High-throughput

0.316

High

1279365

SNAB
Beta-soluble NSF attachment protein

2

0

High-throughput

0.316

High

1279370

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

2

0

High-throughput

0.316

High

1279375

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

1279379

TM140
Transmembrane protein 140

2

0

High-throughput

0.316

High

1279381

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.316

High

1279385

CC167
Coiled-coil domain-containing protein 167

2

0

High-throughput

0.316

High

1279389

FETUB
Fetuin-B

2

0

High-throughput

0.316

High

1279390

NAT8
N-acetyltransferase 8

2

0

High-throughput

0.316

High

1279328

INT1
Integrator complex subunit 1

1

0

High-throughput

0.279

Low

516271

DWORF
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator DWORF

1

0

High-throughput

0.268

Low

60579

TM218
Transmembrane protein 218

1

0

High-throughput

0.251

Low

1279337

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025