HitPredict

Interactor 1: ARP8 (Q9H981)
Actin-related protein 8 (hArp8) (INO80 complex subunit N)
Gene: ACTR8

Interactor 2: RUVB1 (Q9Y265)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (54 kDa erythrocyte cytosolic protein) (ECP-54) (INO80 complex subunit H) (Nuclear matrix protein 238) (NMP 238) (Pontin 52) (TIP49a) (TIP60-associated protein 54-alpha) (TAP54-alpha)
Gene: RUVBL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.79 1.00 0.892

The method score is based on:

Property Details
Experiments 33961781, 17721549, 28514442, 16230350
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~TIP49
Common GO terms GO:0000723 - telomere maintenance
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005813 - centrosome
and 15 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 624
Hs

1 456
+ Mm
+ Hs
+ Sc
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Sc
+ Dm
+ Hs
+ Hs
+ Hs
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024