Protein: SERC
Phosphoserine aminotransferase (EC 2.6.1.52) (Phosphohydroxythreonine aminotransferase) (PSAT)

Gene: SERC, PSAT1
Organism: Homo sapiens
Interactions: 160
UniProt ID: Q9Y617

Gene Ontology (top 5):
GO:0004648 - O-phospho-L-serine:2-oxoglutarate aminotransferase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006564 - L-serine biosynthetic process
GO:0008615 - pyridoxine biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1491793

SERC
Phosphoserine aminotransferase

3

3

High-throughput

0.843

High

1250808

MPRIP
Myosin phosphatase Rho-interacting protein

2

1

High-throughput

0.601

High

698079

CALR
Calreticulin

2

1

High-throughput

0.588

High

158369

COPE
Coatomer subunit epsilon

2

0

High-throughput

0.585

High

243433

PRKN
E3 ubiquitin-protein ligase parkin

2

3

High-throughput

0.584

High

801601

HSPA9
Stress-70 protein, mitochondrial

2

4

High-throughput

0.584

High

295556

PSD10
26S proteasome non-ATPase regulatory subunit 10

2

0

High-throughput

0.583

High

831734

CCNF
Cyclin-F

2

0

High-throughput

0.559

High

1421048

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

2

0

High-throughput

0.559

High

1035032

KPCE
Protein kinase C epsilon type

2

0

High-throughput

0.547

High

1327822

SH2D3
SH2 domain-containing protein 3C

2

0

High-throughput

0.547

High

468962

HS90B
Heat shock protein HSP 90-beta

1

3

Small-scale

0.536

High

922095

COPA
Coatomer subunit alpha

1

1

High-throughput

0.536

High

1491795

SAR1B
Small COPII coat GTPase SAR1B

1

1

High-throughput

0.536

High

1351904

NEK7
Serine/threonine-protein kinase Nek7

1

1

High-throughput

0.515

High

214090

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.513

High

483283

CLCA
Clathrin light chain A

1

0

High-throughput

0.513

High

530675

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.513

High

614747

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

0

High-throughput

0.513

High

1120524

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.513

High

1136092

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1153031

MYLK
Myosin light chain kinase, smooth muscle

1

0

High-throughput

0.513

High

1161284

MK06
Mitogen-activated protein kinase 6

1

1

High-throughput

0.508

High

1153000

CEBPE
CCAAT/enhancer-binding protein epsilon

1

1

High-throughput

0.494

High

556447

CADH1
Cadherin-1

1

0

High-throughput

0.493

High

788284

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

0

High-throughput

0.493

High

423550

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

955800

CDC42
Cell division control protein 42 homolog

1

0

High-throughput

0.480

High

462088

HS90A
Heat shock protein HSP 90-alpha

1

3

Small-scale

0.479

High

508915

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

5

High-throughput

0.479

High

541786

FGFR1
Fibroblast growth factor receptor 1

1

1

High-throughput

0.479

High

668094

CDK2
Cyclin-dependent kinase 2

1

2

High-throughput

0.479

High

772218

MSX2
Homeobox protein MSX-2

1

1

High-throughput

0.479

High

774736

BASI
Basigin

1

1

High-throughput

0.479

High

1038386

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

1

High-throughput

0.479

High

348017

BAG3
BAG family molecular chaperone regulator 3

1

0

High-throughput

0.458

High

487938

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

556891

MYH1
Myosin-1

1

0

High-throughput

0.458

High

577936

PLAK
Junction plakoglobin

1

0

High-throughput

0.458

High

927191

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

935362

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

971372

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

1095015

TRAF3
TNF receptor-associated factor 3

1

0

Small-scale

0.458

High

1107385

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1115177

CUL4A
Cullin-4A

1

0

High-throughput

0.458

High

1229803

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1253255

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

0

High-throughput

0.458

High

1256292

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1289755

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

1335120

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

1364748

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

1388673

SPDLY
Protein Spindly

1

0

High-throughput

0.458

High

1408167

BAG1
BAG family molecular chaperone regulator 1

1

0

High-throughput

0.458

High

1417120

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

1431363

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1459483

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1461068

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.458

High

48854

ESYT2
Extended synaptotagmin-2

1

1

High-throughput

0.445

High

333274

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

1

High-throughput

0.445

High

699297

CALX
Calnexin

1

1

High-throughput

0.445

High

773704

COPB2
Coatomer subunit beta'

1

1

High-throughput

0.445

High

987282

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

4

High-throughput

0.445

High

1316319

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.445

High

1334078

DHB11
Estradiol 17-beta-dehydrogenase 11

1

2

High-throughput

0.445

High

1396073

SCYL1
N-terminal kinase-like protein

1

1

High-throughput

0.445

High

1453864

VAPA
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.445

High

1458364

COPG2
Coatomer subunit gamma-2

1

1

High-throughput

0.445

High

1491794

COPG1
Coatomer subunit gamma-1

1

1

High-throughput

0.445

High

143357

NFIB
Nuclear factor 1 B-type

1

1

High-throughput

0.437

High

412897

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

474408

NFIC
Nuclear factor 1 C-type

1

1

High-throughput

0.437

High

1400433

LMTK3
Serine/threonine-protein kinase LMTK3

1

3

High-throughput

0.437

High

60447

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.426

High

211886

ZW10
Centromere/kinetochore protein zw10 homolog

1

0

High-throughput

0.426

High

213667

VIP2
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2

1

0

High-throughput

0.426

High

215686

EMC8
ER membrane protein complex subunit 8

1

0

High-throughput

0.426

High

296595

STAM2
Signal transducing adapter molecule 2

1

0

High-throughput

0.426

High

319039

MICA2
[F-actin]-monooxygenase MICAL2

1

0

High-throughput

0.426

High

360156

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.426

High

423865

APOD
Apolipoprotein D

1

0

High-throughput

0.426

High

462732

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

535727

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

873356

COPD
Coatomer subunit delta

1

0

High-throughput

0.426

High

877055

KC1A
Casein kinase I isoform alpha

1

0

High-throughput

0.426

High

883168

AL7A1
Alpha-aminoadipic semialdehyde dehydrogenase

1

0

High-throughput

0.426

High

903841

SSRD
Translocon-associated protein subunit delta

1

0

High-throughput

0.426

High

904221

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.426

High

921842

COPB
Coatomer subunit beta

1

0

High-throughput

0.426

High

964089

COPZ1
Coatomer subunit zeta-1

1

0

High-throughput

0.426

High

1009913

NUCB2
Nucleobindin-2

1

0

High-throughput

0.426

High

1015163

ARF5
ADP-ribosylation factor 5

1

0

High-throughput

0.426

High

1097086

PRDX4
Peroxiredoxin-4

1

0

High-throughput

0.426

High

1121570

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.426

High

1131439

GANAB
Neutral alpha-glucosidase AB

1

0

High-throughput

0.426

High

1136427

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.426

High

1139312

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.426

High

1139426

RB3GP
Rab3 GTPase-activating protein catalytic subunit

1

0

High-throughput

0.426

High

1147882

DHC24
Delta(24)-sterol reductase

1

0

High-throughput

0.426

High

1156723

NF2L2
Nuclear factor erythroid 2-related factor 2

1

0

High-throughput

0.426

High

1248694

LCLT1
Lysocardiolipin acyltransferase 1

1

0

High-throughput

0.426

High

1258836

UB2R2
Ubiquitin-conjugating enzyme E2 R2

1

0

High-throughput

0.426

High

1324774

S35F6
Solute carrier family 35 member F6

1

0

High-throughput

0.426

High

1338242

VP37A
Vacuolar protein sorting-associated protein 37A

1

0

High-throughput

0.426

High

1358408

SCFD1
Sec1 family domain-containing protein 1

1

0

High-throughput

0.426

High

1386248

ASTRA
Protein Aster-A

1

0

High-throughput

0.426

High

1401916

NUDC1
NudC domain-containing protein 1

1

0

High-throughput

0.426

High

1412011

PXL2A
Peroxiredoxin-like 2A

1

0

High-throughput

0.426

High

1412175

ERP44
Endoplasmic reticulum resident protein 44

1

0

High-throughput

0.426

High

1413804

NDC1
Nucleoporin NDC1

1

0

High-throughput

0.426

High

1419938

WDR11
WD repeat-containing protein 11

1

0

High-throughput

0.426

High

1430110

RGAP1
Rac GTPase-activating protein 1

1

0

High-throughput

0.426

High

1432086

RBGPR
Rab3 GTPase-activating protein non-catalytic subunit

1

0

High-throughput

0.426

High

1447623

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.426

High

1462728

GAB2
GRB2-associated-binding protein 2

1

0

High-throughput

0.426

High

104383

F5H6I7
Atlastin GTPase 3

1

2

High-throughput

0.407

High

275579

RTN2
Reticulon-2

1

2

High-throughput

0.407

High

329041

RTN3
Reticulon-3

1

2

High-throughput

0.407

High

889056

TMEDA
Transmembrane emp24 domain-containing protein 10

1

2

High-throughput

0.407

High

1146666

TMED2
Transmembrane emp24 domain-containing protein 2

1

2

High-throughput

0.407

High

1199304

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

2

High-throughput

0.407

High

1257240

NEK10
Serine/threonine-protein kinase Nek10

1

1

High-throughput

0.407

High

1340127

ATLA2
Atlastin-2

1

2

High-throughput

0.407

High

1360593

ATLA1
Atlastin-1

1

2

High-throughput

0.407

High

1392424

SYMM
Methionine--tRNA ligase, mitochondrial

1

1

High-throughput

0.407

High

1412741

ESYT1
Extended synaptotagmin-1

1

1

High-throughput

0.407

High

1432785

TMX1
Thioredoxin-related transmembrane protein 1

1

1

High-throughput

0.407

High

1446956

RTN4
Reticulon-4

1

2

High-throughput

0.407

High

1491090

DHRS7
Dehydrogenase/reductase SDR family member 7

1

1

High-throughput

0.407

High

1491125

TMED5
Transmembrane emp24 domain-containing protein 5

1

2

High-throughput

0.407

High

1013125

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

0

High-throughput

0.279

Low

106932

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

332118

MRP6
ATP-binding cassette sub-family C member 6

1

0

Small-scale

0.249

Low

590149

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

590965

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.249

Low

696990

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

769636

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

1127294

RBM39
RNA-binding protein 39

1

0

High-throughput

0.249

Low

50741

HACL2
2-hydroxyacyl-CoA lyase 2

1

0

High-throughput

0.232

Low

261347

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low

283397

ERLN1
Erlin-1

1

0

High-throughput

0.232

Low

522038

H14
Histone H1.4

1

0

High-throughput

0.232

Low

567124

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

0

High-throughput

0.232

Low

1027251

REEP5
Receptor expression-enhancing protein 5

1

0

High-throughput

0.232

Low

1047339

P
P protein

1

0

High-throughput

0.232

Low

1145730

RCN1
Reticulocalbin-1

1

0

High-throughput

0.232

Low

1152901

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

0

High-throughput

0.232

Low

1328013

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

High-throughput

0.232

Low

1330454

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.232

Low

1337748

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.232

Low

1340979

MCFD2
Multiple coagulation factor deficiency protein 2

1

0

High-throughput

0.232

Low

1381559

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.232

Low

1420786

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.232

Low

1421190

LNP
Endoplasmic reticulum junction formation protein lunapark

1

0

High-throughput

0.232

Low

1439753

APMAP
Adipocyte plasma membrane-associated protein

1

0

High-throughput

0.232

Low

1449593

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

1450863

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.232

Low

1451107

GPTC2
G patch domain-containing protein 2

1

0

High-throughput

0.232

Low

1452621

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.232

Low

1452931

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025