Interactor 1: SPC24 (Q8NBT2)
Kinetochore protein Spc24 (hSpc24)
Gene: SPC24
Interactor 2: SPC25 (Q9HBM1)
Kinetochore protein Spc25 (hSpc25)
Gene: SPC25
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 1.00 | 0.978 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 32296183, 33961781, 31839598, 26186194, 26496610, 28514442, 24981860, 22371557, unassigned1304, unassigned3799, 15961401 |
| Identification Methods | two hybrid, affinity chromatography technology, cross-linking study, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, pull down, molecular sieving |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Spc24~Spindle_Spc25 |
| Common GO terms | GO:0000776 - kinetochore GO:0000940 - outer kinetochore GO:0005829 - cytosol GO:0007059 - chromosome segregation GO:0007094 - mitotic spindle assembly checkpoint signaling and 3 others more... |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
