HitPredict

Interactor 1: ANRA2 (Q9H9E1)
Ankyrin repeat family A protein 2 (RFXANK-like protein 2)
Gene: ANKRA2

Interactor 2: HDAC9 (Q9UKV0)
Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)
Gene: HDAC9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.602

Property	Details
Experiments	15964851, 35044719
Identification Methods	pull down, phage display
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0042826 - histone deacetylase binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 313 Hs			1 1011
+	Hs
		149935 RFXK_HUMAN (118-310): 4.26e-68: 214: 63.40		HDAC9_HUMAN (1-1011): 0: 799: 100.00
+	Hs
		880823 ANRA2_HUMAN (1-313): 2.98e-76: 237: 100.00		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Hs
		149843 RFXK_HUMAN (118-310): 4.26e-68: 214: 63.40		HDAC4_HUMAN (1-1009): 0: 691: 54.67
+	Mm
		1157859 RFXK_MOUSE (106-310): 6.79e-67: 212: 56.94		HDAC4_MOUSE (1-1009): 0: 684: 53.86
+	Hs
		1334240 ANRA2_HUMAN (1-313): 2.98e-76: 237: 100.00		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		56845 TANC2_MOUSE (87-313): 8.12e-43: 159: 17.69		HDAC4_MOUSE (1-1009): 0: 684: 53.86
+	Mm
		1112781 ANRA2_MOUSE (1-313): 6.59e-73: 228: 94.89		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Hs
		149938 RFXK_HUMAN (118-310): 4.26e-68: 214: 63.40		HDAC5_HUMAN (1-1008): 0: 612: 55.67
+	Mm
		1112794 RFXK_MOUSE (106-310): 6.79e-67: 212: 56.94		Q3UJF1_MOUSE (1-1008): 0: 609: 54.42
+	Hs
		177384 ANRA2_HUMAN (1-313): 2.98e-76: 237: 100.00		HDAC3_HUMAN (631-1007): 9.3e-131: 404: 22.34
+	Hs
		149897 RFXK_HUMAN (118-310): 4.26e-68: 214: 63.40		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		1038631 EHMT2_HUMAN (79-313): 3.73e-52: 186: 15.61		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		166921 ANR28_HUMAN (5-302): 7.11e-52: 185: 19.80		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		1038721 EHMT1_HUMAN (28-261): 3.89e-47: 171: 19.15		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		1270381 EHMT2_HUMAN (79-313): 3.73e-52: 186: 15.61		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		1270450 EHMT1_HUMAN (28-261): 3.89e-47: 171: 19.15		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		257609 ANR17_HUMAN (16-171): 7.13e-18: 86.4: 8.97		HDAC1_HUMAN (623-1009): 3.2e-140: 430: 23.49
+	Hs
		257678 ANR17_HUMAN (16-171): 7.13e-18: 86.4: 8.97		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67
+	Hs
		1219802 ANKH1_HUMAN (239-312): 2.16e-14: 76: 21.33		HDAC2_HUMAN (622-1009): 4.74e-130: 404: 22.67