Protein: ZNT6
Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)

Gene: ZNT6, SLC30A6
Organism: Homo sapiens
Interactions: 185
UniProt ID: Q6NXT4

Gene Ontology (top 5):
GO:0005385 - zinc ion transmembrane transporter activity
GO:0005794 - Golgi apparatus
GO:0006829 - zinc ion transport
GO:0015297 - antiporter activity
GO:0032588 - trans-Golgi network membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1239521

ZNT5
Proton-coupled zinc antiporter SLC30A5

6

15

Small-scale

0.935

High

1239553

GORS2
Golgi reassembly-stacking protein 2

3

4

High-throughput

0.662

High

648824

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

3

High-throughput

0.628

High

1200976

ACTBL
Beta-actin-like protein 2

3

1

High-throughput

0.609

High

1239504

RIC3
Protein RIC-3

3

2

High-throughput

0.609

High

1239526

MY18A
Unconventional myosin-XVIIIa

3

1

High-throughput

0.609

High

1239562

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

3

4

High-throughput

0.609

High

1239572

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

3

16

High-throughput

0.609

High

1239523

SPP2B
Signal peptide peptidase-like 2B

3

3

High-throughput

0.604

High

636491

FUT3
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3

2

3

High-throughput

0.574

High

669010

FPR2
N-formyl peptide receptor 2

2

18

High-throughput

0.574

High

1239509

TPRA1
Transmembrane protein adipocyte-associated 1

2

1

High-throughput

0.574

High

1239516

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

2

13

High-throughput

0.574

High

396329

ESR1
Estrogen receptor

2

6

High-throughput

0.571

High

1063346

GOGA2
Golgin subfamily A member 2

2

4

High-throughput

0.571

High

1239548

METL9
Protein-L-histidine N-pros-methyltransferase

2

5

High-throughput

0.549

High

719796

V2R
Vasopressin V2 receptor

1

5

High-throughput

0.536

High

723689

NTR1
Neurotensin receptor type 1

1

4

High-throughput

0.536

High

888897

TMEDA
Transmembrane emp24 domain-containing protein 10

1

11

High-throughput

0.536

High

981299

RAB1A
Ras-related protein Rab-1A

1

4

High-throughput

0.536

High

1238986

NIPA3
Magnesium transporter NIPA3

1

1

High-throughput

0.536

High

1239546

RAB1B
Ras-related protein Rab-1B

1

4

High-throughput

0.536

High

1239573

B3GT5
Beta-1,3-galactosyltransferase 5

1

14

High-throughput

0.536

High

1239574

TMED7
Transmembrane emp24 domain-containing protein 7

1

12

High-throughput

0.536

High

291389

NU155
Nuclear pore complex protein Nup155

2

2

High-throughput

0.521

High

829901

PMEL
Melanocyte protein PMEL

1

0

High-throughput

0.513

High

142135

NPT3
Sodium-dependent phosphate transport protein 3

1

3

High-throughput

0.489

High

182594

GP182
G-protein coupled receptor 182

1

11

High-throughput

0.489

High

209380

SIA8C
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3

1

2

High-throughput

0.489

High

595064

KCNA2
Potassium voltage-gated channel subfamily A member 2

1

3

High-throughput

0.489

High

640402

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

7

High-throughput

0.489

High

821733

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

3

High-throughput

0.489

High

833828

P2RY2
P2Y purinoceptor 2

1

12

High-throughput

0.489

High

944918

TMPS3
Transmembrane protease serine 3

1

1

High-throughput

0.489

High

1101531

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

13

High-throughput

0.489

High

1203690

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.489

High

1239501

BTNL9
Butyrophilin-like protein 9

1

3

High-throughput

0.489

High

1239540

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

2

High-throughput

0.489

High

1239545

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.489

High

1239547

F234A
Protein FAM234A

1

1

High-throughput

0.489

High

1239554

NCKX3
Sodium/potassium/calcium exchanger 3

1

2

High-throughput

0.489

High

1239560

TM63C
Osmosensitive cation channel TMEM63C

1

5

High-throughput

0.489

High

1239580

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

2

High-throughput

0.489

High

218332

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

226081

STX6
Syntaxin-6

1

9

High-throughput

0.479

High

327317

ZFPL1
Zinc finger protein-like 1

1

4

High-throughput

0.479

High

373999

RASN
GTPase NRas

1

20

High-throughput

0.479

High

604038

CXA1
Gap junction alpha-1 protein

1

14

High-throughput

0.479

High

630547

RAB3B
Ras-related protein Rab-3B

1

6

High-throughput

0.479

High

827206

ARL1
ADP-ribosylation factor-like protein 1

1

9

High-throughput

0.479

High

901317

RAB7A
Ras-related protein Rab-7a

1

15

High-throughput

0.479

High

901880

RAB9A
Ras-related protein Rab-9A

1

13

High-throughput

0.479

High

956345

RAB2A
Ras-related protein Rab-2A

1

11

High-throughput

0.479

High

976342

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.479

High

1041123

CAV1
Caveolin-1

1

1

High-throughput

0.479

High

1239519

RN149
E3 ubiquitin-protein ligase RNF149

1

12

High-throughput

0.479

High

1239524

RN128
E3 ubiquitin-protein ligase RNF128

1

14

High-throughput

0.479

High

1239525

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

5

High-throughput

0.479

High

1239537

ERGI2
Endoplasmic reticulum-Golgi intermediate compartment protein 2

1

7

High-throughput

0.479

High

1239541

GORS1
Golgi reassembly-stacking protein 1

1

4

High-throughput

0.479

High

1239565

AMFR
E3 ubiquitin-protein ligase AMFR

1

12

High-throughput

0.479

High

331880

GOSR1
Golgi SNAP receptor complex member 1

1

6

High-throughput

0.445

High

920632

ARFP1
Arfaptin-1

1

1

High-throughput

0.445

High

1063130

GOGA3
Golgin subfamily A member 3

1

1

High-throughput

0.445

High

1097801

STX5
Syntaxin-5

1

13

High-throughput

0.445

High

1132280

GOGB1
Golgin subfamily B member 1

1

5

High-throughput

0.445

High

1150916

TRIPB
Thyroid receptor-interacting protein 11

1

5

High-throughput

0.445

High

1239512

LMTK2
Serine/threonine-protein kinase LMTK2

1

6

High-throughput

0.445

High

1239522

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

2

High-throughput

0.445

High

1239535

B3GT6
Beta-1,3-galactosyltransferase 6

1

15

High-throughput

0.445

High

1239536

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

3

High-throughput

0.445

High

1239555

S35C2
Solute carrier family 35 member C2

1

2

High-throughput

0.445

High

1239564

MA1B1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

1

2

High-throughput

0.445

High

1239576

RN115
E3 ubiquitin-protein ligase RNF115

1

4

High-throughput

0.445

High

1239581

S23IP
SEC23-interacting protein

1

1

High-throughput

0.445

High

139899

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

3

High-throughput

0.437

High

179937

BET1
BET1 homolog

1

10

High-throughput

0.437

High

189639

STX7
Syntaxin-7

1

7

High-throughput

0.437

High

302858

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

2

High-throughput

0.437

High

375623

RASK
GTPase KRas

1

20

High-throughput

0.437

High

440120

LCK
Tyrosine-protein kinase Lck

1

3

High-throughput

0.437

High

540507

LAMP1
Lysosome-associated membrane glycoprotein 1

1

16

High-throughput

0.437

High

562147

LAMP2
Lysosome-associated membrane glycoprotein 2

1

16

High-throughput

0.437

High

612250

ARF4
ADP-ribosylation factor 4

1

6

High-throughput

0.437

High

630845

RAB4A
Ras-related protein Rab-4A

1

11

High-throughput

0.437

High

820673

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.437

High

900871

RAB5C
Ras-related protein Rab-5C

1

12

High-throughput

0.437

High

952897

ACTB
Actin, cytoplasmic 1

1

1

High-throughput

0.437

High

962168

RHOA
Transforming protein RhoA

1

15

High-throughput

0.437

High

1004094

CXAR
Coxsackievirus and adenovirus receptor

1

6

High-throughput

0.437

High

1159697

OCLN
Occludin

1

2

High-throughput

0.437

High

1219940

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

2

High-throughput

0.437

High

1226876

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.437

High

1233282

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.437

High

1238711

TECT3
Tectonic-3

1

2

High-throughput

0.437

High

1239506

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

15

High-throughput

0.437

High

1239507

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

1

High-throughput

0.437

High

1239510

TMM17
Transmembrane protein 17

1

2

High-throughput

0.437

High

1239515

CXD3
Gap junction delta-3 protein

1

14

High-throughput

0.437

High

1239518

DHB11
Estradiol 17-beta-dehydrogenase 11

1

6

High-throughput

0.437

High

1239527

ESR2
Estrogen receptor beta

1

6

High-throughput

0.437

High

1239529

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

7

High-throughput

0.437

High

1239530

S2546
Mitochondrial outer membrane protein SLC25A46

1

1

High-throughput

0.437

High

1239549

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

5

High-throughput

0.437

High

1239551

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1239556

SAR1A
Small COPII coat GTPase SAR1A

1

13

High-throughput

0.437

High

1239557

OTULL
Inactive ubiquitin thioesterase OTULINL

1

4

High-throughput

0.437

High

1239558

ELOV5
Very long chain fatty acid elongase 5

1

7

High-throughput

0.437

High

1239559

TM216
Transmembrane protein 216

1

2

High-throughput

0.437

High

1239561

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

6

High-throughput

0.437

High

1239566

ALK
ALK tyrosine kinase receptor

1

2

High-throughput

0.437

High

1239571

LAMP3
Lysosome-associated membrane glycoprotein 3

1

16

High-throughput

0.437

High

1239579

SAR1B
Small COPII coat GTPase SAR1B

1

12

High-throughput

0.437

High

1239550

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.426

High

138172

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

5

High-throughput

0.407

High

161820

RIOK3
Serine/threonine-protein kinase RIO3

1

1

High-throughput

0.407

High

185777

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.407

High

283695

GPC4
Glypican-4

1

1

High-throughput

0.407

High

287573

LRP6
Low-density lipoprotein receptor-related protein 6

1

4

High-throughput

0.407

High

336695

BAG4
BAG family molecular chaperone regulator 4

1

3

High-throughput

0.407

High

347761

BAG3
BAG family molecular chaperone regulator 3

1

3

High-throughput

0.407

High

667910

CDK2
Cyclin-dependent kinase 2

1

1

High-throughput

0.407

High

669337

ACKR3
Atypical chemokine receptor 3

1

14

High-throughput

0.407

High

679352

DNJB2
DnaJ homolog subfamily B member 2

1

2

High-throughput

0.407

High

681416

PSA3
Proteasome subunit alpha type-3

1

7

High-throughput

0.407

High

773543

COPB2
Coatomer subunit beta'

1

9

High-throughput

0.407

High

886077

CXCR3
C-X-C chemokine receptor type 3

1

13

High-throughput

0.407

High

954837

PSA6
Proteasome subunit alpha type-6

1

7

High-throughput

0.407

High

975433

PRS10
26S proteasome regulatory subunit 10B

1

3

High-throughput

0.407

High

1010480

EREP3
Protein ENTREP3

1

2

High-throughput

0.407

High

1036996

DSC2
Desmocollin-2

1

13

High-throughput

0.407

High

1093369

TRI32
E3 ubiquitin-protein ligase TRIM32

1

1

High-throughput

0.407

High

1128338

ITPR2
Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2

1

4

High-throughput

0.407

High

1128520

DSC3
Desmocollin-3

1

11

High-throughput

0.407

High

1148987

SC23B
Protein transport protein Sec23B

1

3

High-throughput

0.407

High

1151548

TRIP6
Thyroid receptor-interacting protein 6

1

2

High-throughput

0.407

High

1198239

FND3B
Fibronectin type III domain-containing protein 3B

1

4

High-throughput

0.407

High

1208921

DCA10
DDB1- and CUL4-associated factor 10

1

1

High-throughput

0.407

High

1210339

NU188
Nucleoporin NUP188

1

1

High-throughput

0.407

High

1216508

BIG3
Brefeldin A-inhibited guanine nucleotide-exchange protein 3

1

7

High-throughput

0.407

High

1239498

TMM88
Transmembrane protein 88

1

2

High-throughput

0.407

High

1239500

GTR7
Solute carrier family 2, facilitated glucose transporter member 7

1

6

High-throughput

0.407

High

1239502

LRIG3
Leucine-rich repeats and immunoglobulin-like domains protein 3

1

2

High-throughput

0.407

High

1239503

CERS6
Ceramide synthase 6

1

6

High-throughput

0.407

High

1239508

IQGA3
Ras GTPase-activating-like protein IQGAP3

1

4

High-throughput

0.407

High

1239514

NPT2C
Sodium-dependent phosphate transport protein 2C

1

3

High-throughput

0.407

High

1239528

USP9X
Ubiquitin carboxyl-terminal hydrolase 9X

1

4

High-throughput

0.407

High

1239533

RSPRY
RING finger and SPRY domain-containing protein 1

1

1

High-throughput

0.407

High

1239534

KIRR1
Kin of IRRE-like protein 1

1

5

High-throughput

0.407

High

1239538

SDF2
Stromal cell-derived factor 2

1

2

High-throughput

0.407

High

1239539

DNJC7
DnaJ homolog subfamily C member 7

1

1

High-throughput

0.407

High

1239542

LZTS2
Leucine zipper putative tumor suppressor 2

1

5

High-throughput

0.407

High

1239543

NUP85
Nuclear pore complex protein Nup85

1

1

High-throughput

0.407

High

1239544

TMM59
Transmembrane protein 59

1

4

High-throughput

0.407

High

1239563

GTR6
Solute carrier family 2, facilitated glucose transporter member 6

1

4

High-throughput

0.407

High

1239567

PCDGK
Protocadherin gamma-C3

1

6

High-throughput

0.407

High

1239569

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

1

High-throughput

0.407

High

1239570

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

1

2

High-throughput

0.407

High

1239577

PCDGH
Protocadherin gamma-B5

1

6

High-throughput

0.407

High

1229813

CYTSA
Cytospin-A

2

0

High-throughput

0.318

High

1239531

CSTOS
Protein CUSTOS

2

0

High-throughput

0.318

High

1239575

HDGR3
Hepatoma-derived growth factor-related protein 3

2

0

High-throughput

0.318

High

1239499

DOK6
Docking protein 6

2

0

High-throughput

0.316

High

1126309

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.279

Low

894825

EMD
Emerin

1

0

High-throughput

0.249

Low

1239517

MLKL
Mixed lineage kinase domain-like protein

1

0

High-throughput

0.249

Low

1239520

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.249

Low

1239552

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low

156140

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

0

High-throughput

0.232

Low

176354

SYNEM
Synemin

1

0

High-throughput

0.232

Low

327608

ELP1
Elongator complex protein 1

1

0

High-throughput

0.232

Low

420810

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

High-throughput

0.232

Low

445561

IF4E
Eukaryotic translation initiation factor 4E

1

0

High-throughput

0.232

Low

911985

DGKE
Diacylglycerol kinase epsilon

1

0

High-throughput

0.232

Low

920045

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.232

Low

1005326

IGBP1
Immunoglobulin-binding protein 1

1

0

High-throughput

0.232

Low

1034004

OCRL
Inositol polyphosphate 5-phosphatase OCRL

1

0

High-throughput

0.232

Low

1117238

NCOA4
Nuclear receptor coactivator 4

1

0

High-throughput

0.232

Low

1159369

ZN239
Zinc finger protein 239

1

0

High-throughput

0.232

Low

1239505

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.232

Low

1239511

HPS6
BLOC-2 complex member HPS6

1

0

High-throughput

0.232

Low

1239513

ABI1
Abl interactor 1

1

0

High-throughput

0.232

Low

1239532

PKHB2
Pleckstrin homology domain-containing family B member 2

1

0

High-throughput

0.232

Low

1239568

ANGE1
Protein angel homolog 1

1

0

High-throughput

0.232

Low

1239578

MAGD1
Melanoma-associated antigen D1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025