HitPredict - High confidence protein-protein interactions

Interactor 1: NHEJ1 (Q9H9Q4)
Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)
Gene: NHEJ1

Interactor 2: NHEJ1 (Q9H9Q4)
Non-homologous end-joining factor 1 (Protein cernunnos) (XRCC4-like factor)
Gene: NHEJ1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.90	0.780

Property	Details
Experiments	17567543, 21768349, 16439205
Identification Methods	affinity chromatography technology, transmission electron microscopy, coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	XLF~XLF
Common GO terms	GO:0001650 - fibrillar center GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005958 - DNA-dependent protein kinase-DNA ligase 4 complex GO:0006303 - double-strand break repair via nonhomologous end joining and 12 others more... GO:0007417 - central nervous system development GO:0010212 - response to ionizing radiation GO:0030183 - B cell differentiation GO:0030217 - T cell differentiation GO:0032807 - DNA ligase IV complex GO:0033152 - immunoglobulin V(D)J recombination GO:0035861 - site of double-strand break GO:0045027 - DNA end binding GO:0051103 - DNA ligation involved in DNA repair GO:0051351 - positive regulation of ligase activity GO:0070182 - DNA polymerase binding GO:0070419 - nonhomologous end joining complex
Homologous interactions	0

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Last updated: 15 Jul 2024