HitPredict

Interactor 1: RPA2 (Q9H9Y6)
DNA-directed RNA polymerase I subunit RPA2 (RNA polymerase I subunit 2) (EC 2.7.7.6) (DNA-directed RNA polymerase I 135 kDa polypeptide) (RPA135)
Gene: POLR1B

Interactor 2: RPA12 (Q9P1U0)
DNA-directed RNA polymerase I subunit RPA12 (DNA-directed RNA polymerase I subunit H) (Zinc ribbon domain-containing protein 1)
Gene: POLR1H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.62 1.00 0.789

The method score is based on:

Property Details
Experiments 24981860, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains RNA_pol_Rpa2_4~TFIIS_C, RNA_pol_Rpb2_1~TFIIS_C, RNA_pol_Rpb2_6~TFIIS_C
Common GO terms GO:0001054 - RNA polymerase I activity
GO:0005654 - nucleoplasm
GO:0005736 - RNA polymerase I complex
GO:0008270 - zinc ion binding
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 1135
Hs

1 126
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Hs
+ Sc
+ Sc
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024