Interactor 1: AGRL3 (Q9HAR2)
Adhesion G protein-coupled receptor L3 (Calcium-independent alpha-latrotoxin receptor 3) (CIRL-3) (Latrophilin-3) (Lectomedin-3)
Gene: ADGRL3

Interactor 2: FLRT3 (Q9NZU0)
Leucine-rich repeat transmembrane protein FLRT3 (Fibronectin-like domain-containing leucine-rich transmembrane protein 3)
Gene: FLRT3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.716

The method score is based on:

Property Details
Experiments 26235030
Identification Methods x-ray crystallography, bio-layer interferometry, molecular sieving
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains LRR_8~OLF
Common GO terms GO:0005886 - plasma membrane
GO:0005911 - cell-cell junction
GO:0007416 - synapse assembly
GO:0098742 - cell-cell adhesion via plasma-membrane adhesion molecules
GO:0098978 - glutamatergic synapse
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 1447
Hs

1 649
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024