HitPredict

Interactor 1: GBB4 (Q9HAV0)
Guanine nucleotide-binding protein subunit beta-4 (Transducin beta chain 4)
Gene: GNB4

Interactor 2: GBG12 (Q9UBI6)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12
Gene: GNG12

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	12782285
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	G-gamma~WD40
Common GO terms	GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 Hs			1 72
+	Hs
		921761 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG12_HUMAN (1-72): 2.14e-28: 98.2: 100.00
+	Hs
		229238 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG7_HUMAN (6-72): 3.3e-27: 95.1: 77.61
+	Hs
		229245 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG7_HUMAN (6-72): 3.3e-27: 95.1: 77.61
+	Hs
		921516 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG3_HUMAN (3-72): 1.94e-26: 93.2: 57.75
+	Hs
		887097 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG2_HUMAN (5-72): 3.25e-26: 92.8: 62.32
+	Hs
		929157 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG3_HUMAN (3-72): 1.94e-26: 93.2: 57.75
+	Hs
		887126 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG2_HUMAN (5-72): 3.25e-26: 92.8: 62.32
+	Hs
		837673 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG4_HUMAN (6-72): 2e-24: 88.2: 57.35
+	Hs
		921771 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG8_HUMAN (5-72): 2.87e-24: 87.8: 49.28
+	Hs
		837687 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG10_HUMAN (6-72): 4.05e-24: 87.4: 44.78
+	Hs
		837682 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG4_HUMAN (6-72): 2e-24: 88.2: 57.35
+	Hs
		837704 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG10_HUMAN (6-72): 4.05e-24: 87.4: 44.78
+	Hs
		921517 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG5_HUMAN (6-72): 9.85e-23: 83.6: 46.27
+	Hs
		929176 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG5_HUMAN (6-72): 9.85e-23: 83.6: 46.27
+	Hs
		921515 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG1_HUMAN (13-71): 8.37e-19: 73.9: 41.67
+	Hs
		929139 Q6FHM2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBG1_HUMAN (13-71): 8.37e-19: 73.9: 41.67
+	Hs
		150115 GBB2_HUMAN (1-340): 1.05e-110: 327: 90.00		GBGT2_HUMAN (14-71): 9.26e-19: 73.5: 43.10
+	Hs
		929145 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG1_HUMAN (13-71): 8.37e-19: 73.9: 41.67
+	Hs
		150117 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBGT2_HUMAN (14-71): 9.26e-19: 73.5: 43.10
+	Hs
		902497 GBB4_HUMAN (1-340): 1.76e-110: 326: 100.00		GBG11_HUMAN (13-71): 1.16e-18: 73.5: 44.07