HitPredict

Interactor 1: TNR27 (Q9HAV5)
Tumor necrosis factor receptor superfamily member 27 (X-linked ectodysplasin-A2 receptor) (EDA-A2 receptor)
Gene: EDA2R

Interactor 2: TRAF6 (Q9Y4K3)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (Interleukin-1 signal transducer) (RING finger protein 85) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.718

The method score is based on:

Property Details
Experiments 26186194, 28514442, 12270937, 33961781, 15280356
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0051092 - positive regulation of NF-kappaB transcription factor activity
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 297
Hs

1 522
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024