HitPredict

Interactor 1: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.12) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Interactor 2: CHD7 (Q9P2D1)
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)
Gene: CHD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.843

The method score is based on:

Property Details
Experiments 24705355, 20453063
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~Chromo, Chromo~SNF2-rel_dom, Helicase_C~Helicase_C, Helicase_C~SNF2-rel_dom, SNF2-rel_dom~SNF2-rel_dom
Common GO terms GO:0000785 - chromatin
GO:0001701 - in utero embryonic development
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
and 7 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 2581
Hs

1 2997
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Last updated: 15 Jul 2024