Interactor 1: Q9I7M8 (Q9I7M8)
ATP-dependent DNA helicase II subunit 2 (EC 3.6.4.12)
Gene: Ku80

Interactor 2: Q9VYA5 (Q9VYA5)
DNA ligase 4 (EC 6.5.1.1) (DNA ligase IV) (Polydeoxyribonucleotide synthase [ATP] 4)
Gene: DNAlig4

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22036573
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BRCT_2~Ku, DNA_ligase_A_N~Ku_N
Common GO terms GO:0000723 - telomere maintenance
GO:0005524 - ATP binding
GO:0006303 - double-strand break repair via nonhomologous end joining
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 699
Dm

1 918
+ Hs
+ Hs
+ Dm
+ Hs
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024