Protein: MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B)

Gene: MCUB
Organism: Homo sapiens
Interactions: 178
UniProt ID: Q9NWR8

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005829 - cytosol
GO:0006851 - mitochondrial calcium ion transmembrane transport
GO:0016020 - membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

418756

GNAI2
Guanine nucleotide-binding protein G(i) subunit alpha-2

3

1

High-throughput

0.667

High

914772

RM12
Large ribosomal subunit protein bL12m

3

2

High-throughput

0.667

High

1086126

ASPH
Aspartyl/asparaginyl beta-hydroxylase

3

1

High-throughput

0.662

High

1337240

MCU
Calcium uniporter protein, mitochondrial

1

6

High-throughput

0.618

High

771251

APJ
Apelin receptor

2

2

High-throughput

0.574

High

1450572

ATD3A
ATPase family AAA domain-containing protein 3A

2

4

High-throughput

0.571

High

1404240

SEC62
Translocation protein SEC62

1

1

High-throughput

0.536

High

1051430

ZBT16
Zinc finger and BTB domain-containing protein 16

1

0

High-throughput

0.518

High

1358413

SCTM1
Secreted and transmembrane protein 1

1

0

High-throughput

0.513

High

378655

IL2RA
Interleukin-2 receptor subunit alpha

1

1

High-throughput

0.489

High

76054

B4DEF8
Large ribosomal subunit protein mL45

1

1

High-throughput

0.479

High

127575

NDUS8
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial

1

1

High-throughput

0.479

High

132885

ODPX
Pyruvate dehydrogenase protein X component, mitochondrial

1

4

High-throughput

0.479

High

143933

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

1

High-throughput

0.479

High

209838

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

1

1

High-throughput

0.479

High

221680

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

1

High-throughput

0.479

High

223902

NDUA2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

1

3

High-throughput

0.479

High

256395

RT14
Small ribosomal subunit protein uS14m

1

1

High-throughput

0.479

High

269066

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

1

High-throughput

0.479

High

275402

NDUS7
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial

1

1

High-throughput

0.479

High

275767

NDUS2
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial

1

1

High-throughput

0.479

High

278761

NDUS6
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial

1

1

High-throughput

0.479

High

283987

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

1

High-throughput

0.479

High

322324

GLSK
Glutaminase kidney isoform, mitochondrial

1

1

High-throughput

0.479

High

328595

NDUA7
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7

1

1

High-throughput

0.479

High

329377

LETM1
Mitochondrial proton/calcium exchanger protein

1

1

High-throughput

0.479

High

359755

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

1

High-throughput

0.479

High

360483

COX2
Cytochrome c oxidase subunit 2

1

1

High-throughput

0.479

High

471283

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

2

High-throughput

0.479

High

522515

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.479

High

539428

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

1

4

High-throughput

0.479

High

560115

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

1

High-throughput

0.479

High

568515

ETFA
Electron transfer flavoprotein subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

622287

NDUV2
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial

1

1

High-throughput

0.479

High

634191

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.479

High

653608

HEMH
Ferrochelatase, mitochondrial

1

1

High-throughput

0.479

High

665732

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

1

High-throughput

0.479

High

702715

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

1

High-throughput

0.479

High

717171

ECHM
Enoyl-CoA hydratase, mitochondrial

1

1

High-throughput

0.479

High

734015

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

3

High-throughput

0.479

High

761044

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

1

High-throughput

0.479

High

766896

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

788232

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.479

High

829566

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.479

High

888771

ACOT2
Acyl-coenzyme A thioesterase 2, mitochondrial

1

3

High-throughput

0.479

High

891050

NDUV1
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial

1

1

High-throughput

0.479

High

902613

RT29
Small ribosomal subunit protein mS29

1

1

High-throughput

0.479

High

940084

NDUV3
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial

1

1

High-throughput

0.479

High

941724

NDUA6
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6

1

1

High-throughput

0.479

High

1011201

RT22
Small ribosomal subunit protein mS22

1

1

High-throughput

0.479

High

1011386

RT25
Small ribosomal subunit protein mS25

1

1

High-throughput

0.479

High

1011541

RT10
Small ribosomal subunit protein uS10m

1

1

High-throughput

0.479

High

1011732

RT35
Small ribosomal subunit protein mS35

1

1

High-throughput

0.479

High

1011914

RT05
Small ribosomal subunit protein uS5m

1

1

High-throughput

0.479

High

1012105

KGD4
Alpha-ketoglutarate dehydrogenase component 4

1

1

High-throughput

0.479

High

1012631

RT34
Small ribosomal subunit protein mS34

1

1

High-throughput

0.479

High

1012776

RT06
Small ribosomal subunit protein bS6m

1

1

High-throughput

0.479

High

1012996

RT09
Small ribosomal subunit protein uS9m

1

1

High-throughput

0.479

High

1035469

ODO1
2-oxoglutarate dehydrogenase complex component E1

1

2

High-throughput

0.479

High

1094138

RM28
Large ribosomal subunit protein bL28m

1

1

High-throughput

0.479

High

1104136

RM49
Large ribosomal subunit protein mL49

1

1

High-throughput

0.479

High

1104770

NNTM
NAD(P) transhydrogenase, mitochondrial

1

1

High-throughput

0.479

High

1123454

ICT1
Large ribosomal subunit protein mL62

1

1

High-throughput

0.479

High

1138898

SYLM
Leucine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

1141559

OXA1L
Mitochondrial inner membrane protein OXA1L

1

1

High-throughput

0.479

High

1162256

NDUA5
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5

1

1

High-throughput

0.479

High

1163542

NDUA9
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial

1

1

High-throughput

0.479

High

1164592

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

1210630

SYVM
Valine--tRNA ligase, mitochondrial

1

3

High-throughput

0.479

High

1214815

ATD3B
ATPase family AAA domain-containing protein 3B

1

2

High-throughput

0.479

High

1215637

ATPF1
ATP synthase mitochondrial F1 complex assembly factor 1

1

1

High-throughput

0.479

High

1235950

PDE12
2',5'-phosphodiesterase 12

1

1

High-throughput

0.479

High

1246022

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

2

High-throughput

0.479

High

1287661

ACOT1
Acyl-coenzyme A thioesterase 1

1

3

High-throughput

0.479

High

1312780

RM41
Large ribosomal subunit protein mL41

1

1

High-throughput

0.479

High

1323242

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

1

1

High-throughput

0.479

High

1328308

RM50
Large ribosomal subunit protein mL50

1

1

High-throughput

0.479

High

1331699

RM43
Large ribosomal subunit protein mL43

1

3

High-throughput

0.479

High

1356892

PTPM1
Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1

1

1

High-throughput

0.479

High

1359812

RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial

1

1

High-throughput

0.479

High

1364404

RT27
Small ribosomal subunit protein mS27

1

1

High-throughput

0.479

High

1366452

RT31
Small ribosomal subunit protein mS31

1

1

High-throughput

0.479

High

1382312

RM24
Large ribosomal subunit protein uL24m

1

1

High-throughput

0.479

High

1385526

P5CR2
Pyrroline-5-carboxylate reductase 2

1

3

High-throughput

0.479

High

1389221

RT24
Small ribosomal subunit protein uS3m

1

1

High-throughput

0.479

High

1390051

PTCD3
Small ribosomal subunit protein mS39

1

1

High-throughput

0.479

High

1390120

MMAB
Corrinoid adenosyltransferase MMAB

1

1

High-throughput

0.479

High

1406064

PHB2
Prohibitin-2

1

3

High-throughput

0.479

High

1410329

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

1

High-throughput

0.479

High

1412455

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1412602

CQ080
Mitochondrial nucleoid-associated protein 1

1

1

High-throughput

0.479

High

1413943

NDUF3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3

1

1

High-throughput

0.479

High

1416563

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

1418150

RM13
Large ribosomal subunit protein uL13m

1

1

High-throughput

0.479

High

1418261

RM04
Large ribosomal subunit protein uL4m

1

1

High-throughput

0.479

High

1418905

RT26
Small ribosomal subunit protein mS26

1

1

High-throughput

0.479

High

1437460

SYCM
Probable cysteine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1449366

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

2

High-throughput

0.479

High

1451264

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

1

High-throughput

0.479

High

1451266

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

1

High-throughput

0.479

High

1451267

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

1

High-throughput

0.479

High

1451269

STML2
Stomatin-like protein 2, mitochondrial

1

1

High-throughput

0.479

High

1451272

RT28
Small ribosomal subunit protein bS1m

1

1

High-throughput

0.479

High

1451273

RT17
Small ribosomal subunit protein uS17m

1

1

High-throughput

0.479

High

1451274

RT07
Small ribosomal subunit protein uS7m

1

1

High-throughput

0.479

High

1451275

RT02
Small ribosomal subunit protein uS2m

1

1

High-throughput

0.479

High

1451277

RT18C
Small ribosomal subunit protein bS18m

1

2

High-throughput

0.479

High

1451278

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

1

1

High-throughput

0.479

High

1451279

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.479

High

1451280

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

1

High-throughput

0.479

High

1451281

RT18B
Small ribosomal subunit protein mS40

1

1

High-throughput

0.479

High

61659

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

156512

ACPM
Acyl carrier protein, mitochondrial

1

0

High-throughput

0.458

High

279947

CISY
Citrate synthase, mitochondrial

1

0

High-throughput

0.458

High

289036

ERAL1
GTPase Era, mitochondrial

1

0

High-throughput

0.458

High

296163

GATB
Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial

1

0

High-throughput

0.458

High

298817

ATP5H
ATP synthase peripheral stalk subunit d, mitochondrial

1

0

High-throughput

0.458

High

353992

NDUBA
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10

1

0

High-throughput

0.458

High

443997

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

0

High-throughput

0.458

High

451284

NFL
Neurofilament light polypeptide

1

0

High-throughput

0.458

High

477875

RM03
Large ribosomal subunit protein uL3m

1

0

High-throughput

0.458

High

483652

CN37
2',3'-cyclic-nucleotide 3'-phosphodiesterase

1

0

High-throughput

0.458

High

539268

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

617611

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.458

High

657403

MAOM
NAD-dependent malic enzyme, mitochondrial

1

0

High-throughput

0.458

High

666370

THIL
Acetyl-CoA acetyltransferase, mitochondrial

1

0

High-throughput

0.458

High

690565

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.458

High

719480

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

0

High-throughput

0.458

High

784745

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.458

High

793774

ETFB
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.458

High

828985

MDHM
Malate dehydrogenase, mitochondrial

1

0

High-throughput

0.458

High

841988

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.458

High

856405

IF2M
Translation initiation factor IF-2, mitochondrial

1

0

High-throughput

0.458

High

1087588

GRSF1
G-rich sequence factor 1

1

0

High-throughput

0.458

High

1271160

TM10C
tRNA methyltransferase 10 homolog C

1

0

High-throughput

0.458

High

1272328

NDUF7
Protein arginine methyltransferase NDUFAF7, mitochondrial

1

0

High-throughput

0.458

High

1275856

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.458

High

1347101

G45IP
Large ribosomal subunit protein mL64

1

0

High-throughput

0.458

High

1387977

RM38
Large ribosomal subunit protein mL38

1

0

High-throughput

0.458

High

1389295

RM53
Large ribosomal subunit protein mL53

1

0

High-throughput

0.458

High

1391623

RM48
Large ribosomal subunit protein mL48

1

0

High-throughput

0.458

High

1409610

NIPS1
Protein NipSnap homolog 1

1

0

High-throughput

0.458

High

1410048

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

0

High-throughput

0.458

High

1418107

RM20
Large ribosomal subunit protein bL20m

1

0

High-throughput

0.458

High

1418205

RM09
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.458

High

1419654

RM37
Large ribosomal subunit protein mL37

1

0

High-throughput

0.458

High

1428747

SLIRP
SRA stem-loop-interacting RNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1429503

CLPB
Mitochondrial disaggregase

1

0

High-throughput

0.458

High

1430519

RM18
Large ribosomal subunit protein uL18m

1

0

High-throughput

0.458

High

1432244

RM46
Large ribosomal subunit protein mL46

1

0

High-throughput

0.458

High

1436111

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

0

High-throughput

0.458

High

1436170

NT5D2
5'-nucleotidase domain-containing protein 2

1

0

High-throughput

0.458

High

1437107

RM44
Large ribosomal subunit protein mL44

1

0

High-throughput

0.458

High

1437805

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

High-throughput

0.458

High

1439603

RM47
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.458

High

1446007

PLPL8
Calcium-independent phospholipase A2-gamma

1

0

High-throughput

0.458

High

1446049

RT30
Large ribosomal subunit protein mL65

1

0

High-throughput

0.458

High

1451262

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.458

High

1451263

RM15
Large ribosomal subunit protein uL15m

1

0

High-throughput

0.458

High

1451265

RM27
Large ribosomal subunit protein bL27m

1

0

High-throughput

0.458

High

1451270

BCS1
Mitochondrial chaperone BCS1

1

0

High-throughput

0.458

High

1451271

RT33
Small ribosomal subunit protein mS33

1

0

High-throughput

0.458

High

1451276

RT16
Small ribosomal subunit protein bS16m

1

0

High-throughput

0.458

High

1451282

NFS1
Cysteine desulfurase

1

0

High-throughput

0.458

High

1451283

RM42
Large ribosomal subunit protein mL42

1

0

High-throughput

0.458

High

171596

S27A2
Long-chain fatty acid transport protein 2

1

2

High-throughput

0.445

High

351259

MOT3
Monocarboxylate transporter 3

1

3

High-throughput

0.445

High

916363

TXTP
Tricarboxylate transport protein, mitochondrial

1

3

High-throughput

0.445

High

1131633

MFS10
Major facilitator superfamily domain-containing protein 10

1

3

High-throughput

0.445

High

1242249

NPAL3
NIPA-like protein 3

1

1

High-throughput

0.445

High

1348071

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

3

High-throughput

0.445

High

1451268

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

1

High-throughput

0.445

High

1005161

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

1236352

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1139852

SETB1
Histone-lysine N-methyltransferase SETDB1

3

0

High-throughput

0.347

High

1386387

FAF2
FAS-associated factor 2

3

0

High-throughput

0.347

High

1394659

TXD15
Thioredoxin domain-containing protein 15

3

0

High-throughput

0.347

High

521975

H14
Histone H1.4

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025