HitPredict

Interactor 1: BUB31 (Q9LJN8)
Mitotic checkpoint protein BUB3.1 (Protein BUDDING UNINHIBITED BY BENZYMIDAZOL 3.1)
Gene: BUB3.1

Interactor 2: CDC21 (Q9SZA4)
Cell division cycle 20.1, cofactor of APC complex (AtCDC20.1)
Gene: CDC20-1

Species: Arabidopsis thaliana

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.621

Property	Details
Experiments	21687678
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0033597 - mitotic checkpoint complex GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 340 At			1 457
+	At
		1338308 BUB31_ARATH (17-340): 2.1e-83: 257: 100.00		CDC22_ARATH (1-457): 7.34e-120: 359: 96.28
+	Hs
		211164 BUB3_HUMAN (4-331): 7.46e-83: 255: 54.10		CDC20_HUMAN (4-457): 8.23e-99: 306: 43.94
+	Hs
		211280 BUB3_HUMAN (4-331): 7.46e-83: 255: 54.10		FZR1_HUMAN (17-457): 5.01e-85: 271: 38.91
+	Hs
		903176 WDR5_HUMAN (179-331): 5.92e-36: 134: 12.18		CDC20_HUMAN (4-457): 8.23e-99: 306: 43.94
+	Hs
		943844 RAE1L_HUMAN (5-333): 1.78e-80: 251: 33.05		SMU1_HUMAN (264-456): 3.66e-42: 158: 21.32
+	Hs
		1288386 SNR40_HUMAN (1-168): 1.1e-36: 137: 14.53		FZR1_HUMAN (17-457): 5.01e-85: 271: 38.91
+	Hs
		211150 BUB3_HUMAN (4-331): 7.46e-83: 255: 54.10		WDR5_HUMAN (306-455): 2.26e-39: 146: 20.53
+	Sc
		640829 BUB3_YEAST (10-320): 4.15e-91: 277: 25.22		CDC20_YEAST (287-446): 1.25e-09: 62.4: 18.29
+	Sp
		999842 TUP11_SCHPO (1-220): 5.76e-68: 225: 17.17		TUP12_SCHPO (294-431): 1.08e-21: 99.7: 26.21
+	Hs
		211260 BUB3_HUMAN (4-331): 7.46e-83: 255: 54.10		NLE1_HUMAN (2-123): 1.08e-11: 68.7: 10.48
+	Hs
		903551 NLE1_HUMAN (88-332): 5.68e-50: 175: 12.16		WDR5_HUMAN (306-455): 2.26e-39: 146: 20.53
+	Hs
		903428 SNR40_HUMAN (1-168): 1.1e-36: 137: 14.53		WDR5_HUMAN (306-455): 2.26e-39: 146: 20.53
+	Hs
		903077 WDR5_HUMAN (179-331): 5.92e-36: 134: 12.18		WDR5_HUMAN (306-455): 2.26e-39: 146: 20.53
+	Hs
		1240442 POC1B_HUMAN (136-340): 1.34e-44: 160: 16.35		POC1A_HUMAN (300-457): 5.38e-28: 116: 13.84
+	Hs
		245633 TBL1R_HUMAN (89-332): 6.38e-47: 167: 13.13		TBL1X_HUMAN (308-454): 8.97e-16: 81.6: 22.22
+	Hs
		1309163 TBL1R_HUMAN (89-332): 6.38e-47: 167: 13.13		TBL1Y_HUMAN (308-456): 1.34e-15: 80.9: 21.95
+	Hs
		1346954 NLE1_HUMAN (88-332): 5.68e-50: 175: 12.16		NLE1_HUMAN (2-123): 1.08e-11: 68.7: 10.48
+	Dm
		1358845 WDS_DROME (129-332): 6.67e-47: 164: 15.39		WDS_DROME (390-457): 1.14e-10: 64.9: 22.06
+	Hs
		792949 WDR5_HUMAN (179-331): 5.92e-36: 134: 12.18		LIS1_HUMAN (398-457): 1.99e-10: 64.5: 20.00
+	Hs
		903349 WDR5_HUMAN (179-331): 5.92e-36: 134: 12.18		WDR5B_HUMAN (390-455): 8.86e-09: 58.7: 19.70