HitPredict

Interactor 1: PCNA1 (Q9M7Q7)
Proliferating cellular nuclear antigen 1 (PCNA 1)
Gene: PCNA

Interactor 2: PCNA2 (Q9ZW35)
Proliferating cell nuclear antigen 2 (PCNA 2)
Gene: PCNA2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	20706207, 23656863
Identification Methods	affinity chromatography technology, protein complementation assay, tandem affinity purification
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	PCNA_C~PCNA_C, PCNA_C~PCNA_N, PCNA_N~PCNA_N
Common GO terms	GO:0003677 - DNA binding GO:0006272 - leading strand elongation GO:0006275 - regulation of DNA replication GO:0006298 - mismatch repair GO:0030337 - DNA polymerase processivity factor activity and 1 others more... GO:0043626 - PCNA complex
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 263 At			1 264
+	At
		1341245 PCNA1_ARATH (1-263): 2.92e-116: 335: 100.00		PCNA1_ARATH (1-263): 8.76e-117: 337: 96.96
+	At
		1378417 PCNA2_ARATH (1-263): 1.94e-115: 333: 96.96		PCNA2_ARATH (1-264): 8.4e-117: 337: 100.00
+	Bt
		1114084 PCNA_BOVIN (1-261): 4.78e-115: 332: 64.75		PCNA_BOVIN (1-261): 2.59e-115: 333: 65.52
+	Dm
		572163 PCNA_DROME (1-260): 1.2e-114: 331: 61.54		PCNA_DROME (1-260): 4.88e-115: 332: 61.54
+	Cg
		884983 PCNA_CRIGR (1-261): 9.42e-115: 331: 64.37		PCNA_CRIGR (1-261): 5.06e-115: 332: 65.13
+	Hs
		517023 PCNA_HUMAN (1-261): 1.84e-114: 330: 64.75		PCNA_HUMAN (1-261): 9.03e-115: 331: 65.52
+	Dm
		572214 PCNA_DROME (1-260): 1.2e-114: 331: 61.54		PCNA2_DROME (1-259): 1.13e-100: 295: 46.33
+	Sp
		976163 PCNA_SCHPO (1-260): 8.96e-104: 303: 53.08		PCNA_SCHPO (1-260): 6.25e-104: 304: 53.08
+	Ce
		137343 PCNA_CAEEL (1-262): 3.27e-102: 300: 51.71		PCNA_CAEEL (1-262): 1.65e-102: 300: 50.19
+	Dm
		1368110 PCNA2_DROME (1-259): 3.6e-100: 294: 46.33		PCNA2_DROME (1-259): 1.13e-100: 295: 46.33
+	Ca
		1124290 Q5AMN0_CANAL (1-259): 6.88e-95: 281: 41.70		Q5AMN0_CANAL (1-259): 3.53e-95: 281: 41.31
+	Sc
		550511 PCNA_YEAST (1-259): 2.24e-94: 280: 40.15		PCNA_YEAST (1-259): 5.53e-95: 281: 39.77
+	Ce
		104901 PCNA_CAEEL (1-262): 3.27e-102: 300: 51.71		MRT2_CAEEL (1-258): 5.66e-58: 187: 18.49
+	Tk
		1126783 PCNA1_THEKO (2-257): 8.79e-77: 234: 21.48		PCNA1_THEKO (2-257): 1.51e-76: 234: 21.09
+	Tk
		1126788 PCNA2_THEKO (2-257): 6.09e-76: 232: 19.46		PCNA2_THEKO (2-257): 7.27e-77: 235: 19.53
+	Hs
		238246 RAD1_HUMAN (4-260): 1.01e-65: 207: 12.22		RAD1_HUMAN (4-260): 5.61e-66: 208: 12.22
+	Dm
		1372520 Q9VQD4_DROME (2-258): 3.09e-19: 86.3: 15.50		Q9VQD4_DROME (2-258): 2.92e-19: 86.3: 14.02
+	Dm
		1196758 Q868I9_DROME (1-36): 7.91e-09: 52: 55.56		Q868I9_DROME (1-36): 3.52e-09: 53.1: 55.56