Protein: OTUD1
OTU domain-containing protein 1 (EC 3.4.19.12) (DUBA-7)

Gene: OTUD1
Organism: Homo sapiens
Interactions: 172
UniProt ID: Q5VV17

Gene Ontology (top 5):
GO:0004843 - cysteine-type deubiquitinase activity
GO:0006508 - proteolysis
GO:0070536 - protein K63-linked deubiquitination

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

475894

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

10

Small-scale

0.696

High

872276

RD23B
UV excision repair protein RAD23 homolog B

2

5

Small-scale

0.694

High

1052887

FLNC
Filamin-C

4

8

Small-scale

0.623

High

1138607

OTUD1
OTU domain-containing protein 1

1

8

Small-scale

0.618

High

325216

AIFM1
Apoptosis-inducing factor 1, mitochondrial

3

1

Small-scale

0.612

High

872174

RD23A
UV excision repair protein RAD23 homolog A

1

3

High-throughput

0.595

High

261277

FLNB
Filamin-B

3

8

Small-scale

0.593

High

598165

FLNA
Filamin-A

3

8

Small-scale

0.593

High

167370

SMAD7
Mothers against decapentaplegic homolog 7

2

1

Small-scale

0.579

High

1038265

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

2

5

Small-scale

0.575

High

803575

BAG6
Large proline-rich protein BAG6

1

4

Small-scale

0.553

High

924321

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

1

Small-scale

0.553

High

790805

CDN2A
Cyclin-dependent kinase inhibitor 2A

2

3

Small-scale

0.533

High

929502

RACK1
Small ribosomal subunit protein RACK1

2

3

Small-scale

0.533

High

1056422

IRF3
Interferon regulatory factor 3

2

2

Small-scale

0.533

High

808684

YAP1
Transcriptional coactivator YAP1

1

3

Small-scale

0.528

High

1026701

PRDX4
Peroxiredoxin-4

1

1

Small-scale

0.528

High

1129872

DCA10
DDB1- and CUL4-associated factor 10

1

1

Small-scale

0.528

High

850084

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.515

High

681893

AKT1
RAC-alpha serine/threonine-protein kinase

1

4

Small-scale

0.512

High

1138628

CARD9
Caspase recruitment domain-containing protein 9

1

1

Small-scale

0.512

High

59671

A4D1J9
Similar to Filamin C

1

6

High-throughput

0.437

High

117160

DX39A
ATP-dependent RNA helicase DDX39A

1

3

High-throughput

0.437

High

151817

IRS4
Insulin receptor substrate 4

1

1

High-throughput

0.437

High

160618

AURKA
Aurora kinase A

1

10

Small-scale

0.437

High

162849

XPO1
Exportin-1

1

6

High-throughput

0.437

High

197324

SERA
D-3-phosphoglycerate dehydrogenase

1

3

High-throughput

0.437

High

235522

VINEX
Vinexin

1

7

High-throughput

0.437

High

269001

CSDE1
Cold shock domain-containing protein E1

1

2

High-throughput

0.437

High

281300

RL1D1
Ribosomal L1 domain-containing protein 1

1

1

High-throughput

0.437

High

321782

WIZ
Protein Wiz

1

1

High-throughput

0.437

High

323825

BAG2
BAG family molecular chaperone regulator 2

1

2

High-throughput

0.437

High

326677

SNAI1
Zinc finger protein SNAI1

1

2

Small-scale

0.437

High

386900

P53
Cellular tumor antigen p53

1

2

Small-scale

0.437

High

398715

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.437

High

438258

HS90B
Heat shock protein HSP 90-beta

1

1

High-throughput

0.437

High

445431

RSSA
Small ribosomal subunit protein uS2

1

2

High-throughput

0.437

High

515875

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

1

High-throughput

0.437

High

516552

PABP1
Polyadenylate-binding protein 1

1

6

Small-scale

0.437

High

537930

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.437

High

563122

YBOX3
Y-box-binding protein 3

1

4

High-throughput

0.437

High

573304

TCPA
T-complex protein 1 subunit alpha

1

2

High-throughput

0.437

High

577985

RL17
Large ribosomal subunit protein uL22

1

1

High-throughput

0.437

High

627283

MCM3
DNA replication licensing factor MCM3

1

3

High-throughput

0.437

High

640506

DDX6
Probable ATP-dependent RNA helicase DDX6

1

5

High-throughput

0.437

High

643876

SYVC
Valine--tRNA ligase

1

2

High-throughput

0.437

High

644062

EF1G
Elongation factor 1-gamma

1

2

High-throughput

0.437

High

646985

1433T
14-3-3 protein theta

1

13

High-throughput

0.437

High

653286

PYR1
Multifunctional protein CAD

1

1

High-throughput

0.437

High

672163

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

1

1

High-throughput

0.437

High

673696

PPIF
Peptidyl-prolyl cis-trans isomerase F, mitochondrial

1

1

High-throughput

0.437

High

681481

DNJA1
DnaJ homolog subfamily A member 1

1

2

High-throughput

0.437

High

682185

AKT2
RAC-beta serine/threonine-protein kinase

1

4

Small-scale

0.437

High

708678

MCM5
DNA replication licensing factor MCM5

1

2

High-throughput

0.437

High

708947

MCM7
DNA replication licensing factor MCM7

1

2

High-throughput

0.437

High

714252

HSP74
Heat shock 70 kDa protein 4

1

1

High-throughput

0.437

High

717154

CTNB1
Catenin beta-1

1

1

Small-scale

0.437

High

730284

PRS7
26S proteasome regulatory subunit 7

1

1

High-throughput

0.437

High

821256

TCPE
T-complex protein 1 subunit epsilon

1

2

High-throughput

0.437

High

826704

TCPG
T-complex protein 1 subunit gamma

1

2

High-throughput

0.437

High

834613

NU153
Nuclear pore complex protein Nup153

1

8

High-throughput

0.437

High

842906

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.437

High

843730

FXR1
RNA-binding protein FXR1

1

8

High-throughput

0.437

High

858272

TXTP
Tricarboxylate transport protein, mitochondrial

1

1

High-throughput

0.437

High

892828

IF4A1
Eukaryotic initiation factor 4A-I

1

4

High-throughput

0.437

High

905657

RS7
Small ribosomal subunit protein eS7

1

2

High-throughput

0.437

High

907061

PRS8
26S proteasome regulatory subunit 8

1

1

High-throughput

0.437

High

909661

1433E
14-3-3 protein epsilon

1

2

High-throughput

0.437

High

915217

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

2

High-throughput

0.437

High

919420

RL23
Large ribosomal subunit protein uL14

1

3

High-throughput

0.437

High

920220

RS24
Small ribosomal subunit protein eS24

1

1

High-throughput

0.437

High

923703

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.437

High

927828

2ABA
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform

1

1

High-throughput

0.437

High

930085

ACTH
Actin, gamma-enteric smooth muscle

1

3

High-throughput

0.437

High

933847

TBB4B
Tubulin beta-4B chain

1

2

High-throughput

0.437

High

950202

SMAD3
Mothers against decapentaplegic homolog 3

1

1

Small-scale

0.437

High

979924

IF4G1
Eukaryotic translation initiation factor 4 gamma 1

1

4

High-throughput

0.437

High

980399

NOTC2
Neurogenic locus notch homolog protein 2

1

2

Small-scale

0.437

High

988941

FMR1
Fragile X messenger ribonucleoprotein 1

1

8

High-throughput

0.437

High

989317

PRDX1
Peroxiredoxin-1

1

1

High-throughput

0.437

High

1025784

TADBP
TAR DNA-binding protein 43

1

7

High-throughput

0.437

High

1041771

CUL3
Cullin-3

1

2

Small-scale

0.437

High

1043047

CUL4A
Cullin-4A

1

2

Small-scale

0.437

High

1044550

FHL1
Four and a half LIM domains protein 1

1

2

High-throughput

0.437

High

1049576

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

3

High-throughput

0.437

High

1052681

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

11

High-throughput

0.437

High

1053878

CAPR1
Caprin-1

1

3

High-throughput

0.437

High

1071041

IRF4
Interferon regulatory factor 4

1

2

Small-scale

0.437

High

1072107

PCBP2
Poly(rC)-binding protein 2

1

5

Small-scale

0.437

High

1073962

SC23A
Protein transport protein Sec23A

1

1

High-throughput

0.437

High

1074045

SC23B
Protein transport protein Sec23B

1

1

High-throughput

0.437

High

1127619

PRC2B
Protein PRRC2B

1

11

High-throughput

0.437

High

1138609

H3C
Histone H3.3C

1

2

High-throughput

0.437

High

1138611

SND1
Staphylococcal nuclease domain-containing protein 1

1

1

High-throughput

0.437

High

1138612

DHX30
ATP-dependent RNA helicase DHX30

1

4

High-throughput

0.437

High

1138614

ZN598
E3 ubiquitin-protein ligase ZNF598

1

3

High-throughput

0.437

High

1138615

PGAM4
Probable phosphoglycerate mutase 4

1

1

Small-scale

0.437

High

1138616

AHI1
Jouberin

1

2

Small-scale

0.437

High

1138617

CCAR2
Cell cycle and apoptosis regulator protein 2

1

2

Small-scale

0.437

High

1138619

SMRC1
SWI/SNF complex subunit SMARCC1

1

7

Small-scale

0.437

High

1138620

FUBP2
Far upstream element-binding protein 2

1

10

High-throughput

0.437

High

1138621

IRF7
Interferon regulatory factor 7

1

2

Small-scale

0.437

High

1138623

FUBP3
Far upstream element-binding protein 3

1

10

High-throughput

0.437

High

1138624

CDC5L
Cell division cycle 5-like protein

1

1

High-throughput

0.437

High

1138625

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.437

High

1138627

YTHD1
YTH domain-containing family protein 1

1

8

High-throughput

0.437

High

1138630

BRD9
Bromodomain-containing protein 9

1

2

High-throughput

0.437

High

1138632

SMUF1
E3 ubiquitin-protein ligase SMURF1

1

1

Small-scale

0.437

High

1138635

LANC2
LanC-like protein 2

1

1

High-throughput

0.437

High

1138636

ATD3A
ATPase family AAA domain-containing protein 3A

1

1

High-throughput

0.437

High

1138639

DIC
Mitochondrial dicarboxylate carrier

1

1

High-throughput

0.437

High

1138642

TNR6B
Trinucleotide repeat-containing gene 6B protein

1

6

Small-scale

0.437

High

1138643

AKT3
RAC-gamma serine/threonine-protein kinase

1

4

Small-scale

0.437

High

1049228

KEAP1
Kelch-like ECH-associated protein 1

3

0

Small-scale

0.339

High

82420

IGLL5
Immunoglobulin lambda-like polypeptide 5

1

0

High-throughput

0.249

Low

198651

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

High-throughput

0.249

Low

206752

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.249

Low

311249

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

1

0

High-throughput

0.249

Low

352638

TNFA
Tumor necrosis factor

1

0

Small-scale

0.249

Low

388505

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.249

Low

390287

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.249

Low

414955

CDK1
Cyclin-dependent kinase 1

1

0

High-throughput

0.249

Low

415365

ATPB
ATP synthase subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

437761

PFKAM
ATP-dependent 6-phosphofructokinase, muscle type

1

0

High-throughput

0.249

Low

505727

UMPS
Uridine 5'-monophosphate synthase

1

0

High-throughput

0.249

Low

514018

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

0

High-throughput

0.249

Low

518383

ADT3
ADP/ATP translocase 3

1

0

High-throughput

0.249

Low

523813

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.249

Low

606433

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

0

High-throughput

0.249

Low

643758

SYTC
Threonine--tRNA ligase 1, cytoplasmic

1

0

High-throughput

0.249

Low

649552

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

678631

METK2
S-adenosylmethionine synthase isoform type-2

1

0

High-throughput

0.249

Low

773405

RL13A
Large ribosomal subunit protein uL13

1

0

High-throughput

0.249

Low

785958

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.249

Low

789836

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

0

High-throughput

0.249

Low

800012

VDAC2
Voltage-dependent anion-selective channel protein 2

1

0

High-throughput

0.249

Low

802121

NOP2
Probable 28S rRNA

1

0

High-throughput

0.249

Low

816014

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.249

Low

853319

IMA1
Importin subunit alpha-1

1

0

High-throughput

0.249

Low

854312

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.249

Low

879682

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.249

Low

890201

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.249

Low

899228

RL15
Large ribosomal subunit protein eL15

1

0

High-throughput

0.249

Low

912658

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.249

Low

942180

GTF2I
General transcription factor II-I

1

0

High-throughput

0.249

Low

990111

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

Small-scale

0.249

Low

992172

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

0

Small-scale

0.249

Low

997763

RBBP4
Histone-binding protein RBBP4

1

0

High-throughput

0.249

Low

1026292

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.249

Low

1034309

SF3B2
Splicing factor 3B subunit 2

1

0

High-throughput

0.249

Low

1039623

SNW1
SNW domain-containing protein 1

1

0

High-throughput

0.249

Low

1060778

IMB1
Importin subunit beta-1

1

0

High-throughput

0.249

Low

1072757

TOM20
Mitochondrial import receptor subunit TOM20 homolog

1

0

Small-scale

0.249

Low

1082227

DDB1
DNA damage-binding protein 1

1

0

Small-scale

0.249

Low

1133168

CAF17
Putative transferase CAF17, mitochondrial

1

0

High-throughput

0.249

Low

1138608

DRS7B
Dehydrogenase/reductase SDR family member 7B

1

0

High-throughput

0.249

Low

1138610

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

Small-scale

0.249

Low

1138613

PEG10
Retrotransposon-derived protein PEG10

1

0

High-throughput

0.249

Low

1138618

MIA40
Mitochondrial intermembrane space import and assembly protein 40

1

0

Small-scale

0.249

Low

1138622

PGAM5
Serine/threonine-protein phosphatase PGAM5, mitochondrial

1

0

Small-scale

0.249

Low

1138626

PDD2L
Programmed cell death protein 2-like

1

0

High-throughput

0.249

Low

1138629

GCP60
Golgi resident protein GCP60

1

0

High-throughput

0.249

Low

1138631

TM165
Putative divalent cation/proton antiporter TMEM165

1

0

Small-scale

0.249

Low

1138633

DBLOH
Diablo IAP-binding mitochondrial protein

1

0

Small-scale

0.249

Low

1138634

AAAS
Aladin

1

0

High-throughput

0.249

Low

1138637

CARF
CDKN2A-interacting protein

1

0

High-throughput

0.249

Low

1138638

TECR
Very-long-chain enoyl-CoA reductase

1

0

High-throughput

0.249

Low

1138640

IP6K2
Inositol hexakisphosphate kinase 2

1

0

High-throughput

0.249

Low

1138641

STML2
Stomatin-like protein 2, mitochondrial

1

0

High-throughput

0.249

Low

1138644

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.249

Low

1138645

RTCB
RNA-splicing ligase RtcB homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024